Table 12 Open in new tab Performances of...

Table 12

Performances of AMPfun and existing AMP prediction tools based on the independent testing set

Activities	Tool	SN	SP	ACC	MCC	AUC
Anti-viral	AMPfun	0.9085	0.8406	0.8613	0.7075	0.9404
	iAMPpred [28]	0.3128	0.3959	0.3706	−0.2682	0.3158
	AVPpred [34]	0.2409	0.8857	0.6901	0.1643	N/A
Anti-cancer	AMPfun	0.7766	0.7060	0.7094	0.2208	0.8231
Anti-cancer	MLACP [21]	0.7234	0.7512	0.7499	0.2272	0.8320
Anti-fungal	AMPfun	0.8561	0.6675	0.7458	0.5186	0.8578
Anti-fungal	iAMPpred [28]	0.6610	0.7212	0.6962	0.3796	0.7412
Anti-fungal	AMPfun	0.7929	0.7455	0.7678	0.5375	0.8448
Anti-fungal	AntiFP [19]	0.6699	0.7039	0.6879	0.3737	N/A
Targeting Gram-positive bacteria	AMPfun	0.8829	0.6282	0.7385	0.5155	0.8653
Targeting Gram-positive bacteria	iAMPpred [28]	0.6872	0.6541	0.6684	0.3382	0.6950
Targeting Gram-negative bacteria	AMPfun	0.8563	0.6522	0.7406	0.5086	0.8590
Targeting Gram-negative bacteria	iAMPpred [28]	0.6932	0.6568	0.6726	0.3469	0.6958

Activities	Tool	SN	SP	ACC	MCC	AUC
Anti-viral	AMPfun	0.9085	0.8406	0.8613	0.7075	0.9404
	iAMPpred [28]	0.3128	0.3959	0.3706	−0.2682	0.3158
	AVPpred [34]	0.2409	0.8857	0.6901	0.1643	N/A
Anti-cancer	AMPfun	0.7766	0.7060	0.7094	0.2208	0.8231
Anti-cancer	MLACP [21]	0.7234	0.7512	0.7499	0.2272	0.8320
Anti-fungal	AMPfun	0.8561	0.6675	0.7458	0.5186	0.8578
Anti-fungal	iAMPpred [28]	0.6610	0.7212	0.6962	0.3796	0.7412
Anti-fungal	AMPfun	0.7929	0.7455	0.7678	0.5375	0.8448
Anti-fungal	AntiFP [19]	0.6699	0.7039	0.6879	0.3737	N/A
Targeting Gram-positive bacteria	AMPfun	0.8829	0.6282	0.7385	0.5155	0.8653
Targeting Gram-positive bacteria	iAMPpred [28]	0.6872	0.6541	0.6684	0.3382	0.6950
Targeting Gram-negative bacteria	AMPfun	0.8563	0.6522	0.7406	0.5086	0.8590
Targeting Gram-negative bacteria	iAMPpred [28]	0.6932	0.6568	0.6726	0.3469	0.6958

Note: N/A means that we could not derive the values from the provided results. SN, sensitivity; SP, specificity; ACC, accuracy; MCC, Matthews correlation coefficient; AUC, area under the receiver operating characteristic curve.

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