Table 1 Open in new tab Reported human...

Table 1

Reported human embryo editing experiment

Study	Embryo type	Gene	Off-target effect	Mosaicism detected?
Liang et al., 2015	Zygote 3PN	HBB	√	√
Kang et al., 2016	Zygote 3PN	CCR5	No (at studied sites)	√
Tang et al., 2017	Zygote 3PN	HBB&G6PD	No determined	√
Hong et al., 2017	Zygote 2PN Gamete 2PN	MYBPC3	No determined	√
Yanting et al., 2018	Gamete 2PN	FBN1T7498C	No	No

Study	Embryo type	Gene	Off-target effect	Mosaicism detected?
Liang et al., 2015	Zygote 3PN	HBB	√	√
Kang et al., 2016	Zygote 3PN	CCR5	No (at studied sites)	√
Tang et al., 2017	Zygote 3PN	HBB&G6PD	No determined	√
Hong et al., 2017	Zygote 2PN Gamete 2PN	MYBPC3	No determined	√
Yanting et al., 2018	Gamete 2PN	FBN1T7498C	No	No