| Variable . | Vaccine Dose Received, by Age . | Challenge Dose Received, Age 22 wk . | Follow-up, Age 23 wk . | |||
|---|---|---|---|---|---|---|
| Birth . | 6 wk . | 10 wk . | 14 wk . | |||
| Study arm | ||||||
| A | IPV | IPV | IPV | IPV | tOPV | … |
| B | bOPV | bOPV | bOPV | bOPV | tOPV | … |
| C | bOPV | bOPV | bOPV | bOPV and IPV | tOPV | … |
| D | bOPV | bOPV | bOPV | bOPV and IPV | tOPV and IPV | … |
| E | tOPV | tOPV | tOPV | tOPV | tOPV | … |
| Sample(s) collected | Cord or peripheral blood | Peripheral blood | Peripheral blood | Blood | Blood and stool | Stool |
| Variable . | Vaccine Dose Received, by Age . | Challenge Dose Received, Age 22 wk . | Follow-up, Age 23 wk . | |||
|---|---|---|---|---|---|---|
| Birth . | 6 wk . | 10 wk . | 14 wk . | |||
| Study arm | ||||||
| A | IPV | IPV | IPV | IPV | tOPV | … |
| B | bOPV | bOPV | bOPV | bOPV | tOPV | … |
| C | bOPV | bOPV | bOPV | bOPV and IPV | tOPV | … |
| D | bOPV | bOPV | bOPV | bOPV and IPV | tOPV and IPV | … |
| E | tOPV | tOPV | tOPV | tOPV | tOPV | … |
| Sample(s) collected | Cord or peripheral blood | Peripheral blood | Peripheral blood | Blood | Blood and stool | Stool |
Abbreviations: bOPV, bivalent oral poliovirus vaccine; IPV, inactivated poliovirus vaccine; tOPV, trivalent oral poliovirus vaccine.
| Variable . | Vaccine Dose Received, by Age . | Challenge Dose Received, Age 22 wk . | Follow-up, Age 23 wk . | |||
|---|---|---|---|---|---|---|
| Birth . | 6 wk . | 10 wk . | 14 wk . | |||
| Study arm | ||||||
| A | IPV | IPV | IPV | IPV | tOPV | … |
| B | bOPV | bOPV | bOPV | bOPV | tOPV | … |
| C | bOPV | bOPV | bOPV | bOPV and IPV | tOPV | … |
| D | bOPV | bOPV | bOPV | bOPV and IPV | tOPV and IPV | … |
| E | tOPV | tOPV | tOPV | tOPV | tOPV | … |
| Sample(s) collected | Cord or peripheral blood | Peripheral blood | Peripheral blood | Blood | Blood and stool | Stool |
| Variable . | Vaccine Dose Received, by Age . | Challenge Dose Received, Age 22 wk . | Follow-up, Age 23 wk . | |||
|---|---|---|---|---|---|---|
| Birth . | 6 wk . | 10 wk . | 14 wk . | |||
| Study arm | ||||||
| A | IPV | IPV | IPV | IPV | tOPV | … |
| B | bOPV | bOPV | bOPV | bOPV | tOPV | … |
| C | bOPV | bOPV | bOPV | bOPV and IPV | tOPV | … |
| D | bOPV | bOPV | bOPV | bOPV and IPV | tOPV and IPV | … |
| E | tOPV | tOPV | tOPV | tOPV | tOPV | … |
| Sample(s) collected | Cord or peripheral blood | Peripheral blood | Peripheral blood | Blood | Blood and stool | Stool |
Abbreviations: bOPV, bivalent oral poliovirus vaccine; IPV, inactivated poliovirus vaccine; tOPV, trivalent oral poliovirus vaccine.
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