| HFpEF | HFmrEF | HFrEF | |
| Criterion 1 | Symptoms and/or signsa | Symptoms and/or signsa | Symptoms and/or signsa |
| Criterion 2 | LVEF ≥50% | LVEF 40–49% | LVEF <40% |
| Criterion 3 | 1. Elevated natriuretic peptidesb | 1. Elevated natriuretic peptidesb | None |
| 2. At least one additional criterion: | 2. At least one additional criterion: | ||
| a) structural heart disease (i.e. LVH and/or LAE) | a) structural heart disease (i.e. LVH and/or LAE) | ||
| b) diastolic dysfunctionc | b) diastolic dysfunctionc |
| HFpEF | HFmrEF | HFrEF | |
| Criterion 1 | Symptoms and/or signsa | Symptoms and/or signsa | Symptoms and/or signsa |
| Criterion 2 | LVEF ≥50% | LVEF 40–49% | LVEF <40% |
| Criterion 3 | 1. Elevated natriuretic peptidesb | 1. Elevated natriuretic peptidesb | None |
| 2. At least one additional criterion: | 2. At least one additional criterion: | ||
| a) structural heart disease (i.e. LVH and/or LAE) | a) structural heart disease (i.e. LVH and/or LAE) | ||
| b) diastolic dysfunctionc | b) diastolic dysfunctionc |
HF = heart failure; HFmrEF = heart failure with mid-range ejection fraction; HFpEF = heart failure with preserved ejection fraction; HFrEF = heart failure with reduced ejection fraction; LAE = left atrial enlargement; LVEF = left ventricular ejection fraction; LVH = left ventricular hypertrophy; NT-proBNP = N-terminal pro-B-type natriuretic peptide.
Signs may not be present at an early stage or in patients receiving diuretics.
Elevation of B-type natriuretic peptide ≥35 pg/mL and/or NT-proBNP ≥125 pg/mL.
For example, E/e′ ≥13, and a mean e’ septal and lateral wall <9 cm/s on echocardiography.
| HFpEF | HFmrEF | HFrEF | |
| Criterion 1 | Symptoms and/or signsa | Symptoms and/or signsa | Symptoms and/or signsa |
| Criterion 2 | LVEF ≥50% | LVEF 40–49% | LVEF <40% |
| Criterion 3 | 1. Elevated natriuretic peptidesb | 1. Elevated natriuretic peptidesb | None |
| 2. At least one additional criterion: | 2. At least one additional criterion: | ||
| a) structural heart disease (i.e. LVH and/or LAE) | a) structural heart disease (i.e. LVH and/or LAE) | ||
| b) diastolic dysfunctionc | b) diastolic dysfunctionc |
| HFpEF | HFmrEF | HFrEF | |
| Criterion 1 | Symptoms and/or signsa | Symptoms and/or signsa | Symptoms and/or signsa |
| Criterion 2 | LVEF ≥50% | LVEF 40–49% | LVEF <40% |
| Criterion 3 | 1. Elevated natriuretic peptidesb | 1. Elevated natriuretic peptidesb | None |
| 2. At least one additional criterion: | 2. At least one additional criterion: | ||
| a) structural heart disease (i.e. LVH and/or LAE) | a) structural heart disease (i.e. LVH and/or LAE) | ||
| b) diastolic dysfunctionc | b) diastolic dysfunctionc |
HF = heart failure; HFmrEF = heart failure with mid-range ejection fraction; HFpEF = heart failure with preserved ejection fraction; HFrEF = heart failure with reduced ejection fraction; LAE = left atrial enlargement; LVEF = left ventricular ejection fraction; LVH = left ventricular hypertrophy; NT-proBNP = N-terminal pro-B-type natriuretic peptide.
Signs may not be present at an early stage or in patients receiving diuretics.
Elevation of B-type natriuretic peptide ≥35 pg/mL and/or NT-proBNP ≥125 pg/mL.
For example, E/e′ ≥13, and a mean e’ septal and lateral wall <9 cm/s on echocardiography.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
