Table 3 Open in new tab Infection-free...

	Univariate analysis	Multivariate analysis
Age	1.05	1.01–1.09	0.011
BMI	1.05	0.99–1.12	0.107
Diabetes mellitus	2.08	1.05–4.11	0.036	2.58	1.28–5.19	0.008
History of CE	1.89	0.85–4.20	0.118
Chronic heart failure	1.83	0.92–3.66	0.087
PD versus HD	2.78	2.40–5.53	0.004	3.18	1.52–6.64	0.002
Dialysis duration (month)	1.00	0.99–1.01	0.766
CRP (mg/L)	1.05	1.01–1.09	0.029	1.06	1.01–1.11	0.009
Ferritin (ng/L)	0.99	0.99–1.00	0.127
Low thymic output (first and second versus third tertile)	2.42	1.00–5.85	0.050	1.79	1.34–9.58	0.011

	Univariate analysis	Multivariate analysis
Age	1.05	1.01–1.09	0.011
BMI	1.05	0.99–1.12	0.107
Diabetes mellitus	2.08	1.05–4.11	0.036	2.58	1.28–5.19	0.008
History of CE	1.89	0.85–4.20	0.118
Chronic heart failure	1.83	0.92–3.66	0.087
PD versus HD	2.78	2.40–5.53	0.004	3.18	1.52–6.64	0.002
Dialysis duration (month)	1.00	0.99–1.01	0.766
CRP (mg/L)	1.05	1.01–1.09	0.029	1.06	1.01–1.11	0.009
Ferritin (ng/L)	0.99	0.99–1.00	0.127
Low thymic output (first and second versus third tertile)	2.42	1.00–5.85	0.050	1.79	1.34–9.58	0.011

Table 3

Infection-free survival performed with Cox model regression in univariate analysis then we selected variables with P-values <0.2 for multivariate model analysis step by step on dialysed patients

	Univariate analysis			Multivariate analysis
Factors	HR	95% CI	P-value	HR	95% CI	P-value
Age	1.05	1.01–1.09	0.011
BMI	1.05	0.99–1.12	0.107
Diabetes mellitus	2.08	1.05–4.11	0.036	2.58	1.28–5.19	0.008
History of CE	1.89	0.85–4.20	0.118
Chronic heart failure	1.83	0.92–3.66	0.087
PD versus HD	2.78	2.40–5.53	0.004	3.18	1.52–6.64	0.002
Dialysis duration (month)	1.00	0.99–1.01	0.766
CRP (mg/L)	1.05	1.01–1.09	0.029	1.06	1.01–1.11	0.009
Ferritin (ng/L)	0.99	0.99–1.00	0.127
Low thymic output (first and second versus third tertile)	2.42	1.00–5.85	0.050	1.79	1.34–9.58	0.011

	Univariate analysis			Multivariate analysis
Factors	HR	95% CI	P-value	HR	95% CI	P-value
Age	1.05	1.01–1.09	0.011
BMI	1.05	0.99–1.12	0.107
Diabetes mellitus	2.08	1.05–4.11	0.036	2.58	1.28–5.19	0.008
History of CE	1.89	0.85–4.20	0.118
Chronic heart failure	1.83	0.92–3.66	0.087
PD versus HD	2.78	2.40–5.53	0.004	3.18	1.52–6.64	0.002
Dialysis duration (month)	1.00	0.99–1.01	0.766
CRP (mg/L)	1.05	1.01–1.09	0.029	1.06	1.01–1.11	0.009
Ferritin (ng/L)	0.99	0.99–1.00	0.127
Low thymic output (first and second versus third tertile)	2.42	1.00–5.85	0.050	1.79	1.34–9.58	0.011

Thymic output quantified by RTE CD4⁺CD45RA⁺CD31⁺ T cells are expressed in tertiles. Low thymic ouput was first and second tertiles. Duration of dialysis was forced in this model because of its clinical relevance.

HR: hazard ratio, BMI: body mass index, CE: cardiovascular event, CRP: C reactive protein.

This Feature Is Available To Subscribers Only