Congenital CMV Infection Birth Prevalence Rates and Symptomatic Disease Estimates in Neonates Born in Highly Seropositive Populations
| Country, Author(s) (Year) [Ref.] . | Maternal CMV Seroprevalence (%) . | cCMV Infection Birth Prevalence Rate (cCMV/Screened) . | Symptomatic cCMV Prevalence Rate (Symptomatic/Screened) . | Proportion of Symptomatic cCMV . |
|---|---|---|---|---|
| Ivory Coast, Schopfer et al (1978) [32] | 99.7 | 14:1000 (28/2132) | 0:1000 | 0.0% |
| The Gambia, van der Sande et al (2007) [26] | 100.0 | 54:1000 (40/741) | 0:1000 | 0.0% |
| Nigeria, Olusanya et al (2015) [39] | 97.2 | 38:1000 (10/263) | 7.6:1000 | 20.0% (2/10) |
| Israel, Schlesinger et al (2003) [41] | 80.5–85.0 | 7:1000 (14/2000) | 0.5:1000 | 9.0% (1/14) |
| Mexico, Noyola et al (2003) [40] | 91.6 | 9:1000 (5/599) | 0:1000 | 0.0% |
| Japan, Numazaki and Fujikawa (2004) [42] | 85.0 | 3:1000 (37/11 938) | 0.4:1000 | 13.5% (5/37) |
| Japan, Kamada et al (1983) [43] | 93.7 | 5:1000 (11/2070) | 0:1000 | 0.0% |
| USA, Fowler et al (1993) [44] | Low incomea | 12:1000 (215/17 163) | 0.9:1000 | 7.4% (16/215) |
| Brazil, Mussi-Pinhata et al [31, 45, 46] | 96.7 | 8:1000 (189/24 095) | 0.9:1000 | 11.1% (12/121) |
| India, Dar et al (2008) [38] | 99.0 | 21:1000 (9/419) | 2.3:1000 | 11.1% (1/9) |
| China, Zhang et al (2007) [47] | 93.1 | 61:1000 (71/1159) | 14.6:1000 | 23.9% (17/71) |
| China, Wang et al (2017) [27] | 96.2% | 7:1000 (75/10 933) | 0.0:1000 | 0.0% |
| Country, Author(s) (Year) [Ref.] . | Maternal CMV Seroprevalence (%) . | cCMV Infection Birth Prevalence Rate (cCMV/Screened) . | Symptomatic cCMV Prevalence Rate (Symptomatic/Screened) . | Proportion of Symptomatic cCMV . |
|---|---|---|---|---|
| Ivory Coast, Schopfer et al (1978) [32] | 99.7 | 14:1000 (28/2132) | 0:1000 | 0.0% |
| The Gambia, van der Sande et al (2007) [26] | 100.0 | 54:1000 (40/741) | 0:1000 | 0.0% |
| Nigeria, Olusanya et al (2015) [39] | 97.2 | 38:1000 (10/263) | 7.6:1000 | 20.0% (2/10) |
| Israel, Schlesinger et al (2003) [41] | 80.5–85.0 | 7:1000 (14/2000) | 0.5:1000 | 9.0% (1/14) |
| Mexico, Noyola et al (2003) [40] | 91.6 | 9:1000 (5/599) | 0:1000 | 0.0% |
| Japan, Numazaki and Fujikawa (2004) [42] | 85.0 | 3:1000 (37/11 938) | 0.4:1000 | 13.5% (5/37) |
| Japan, Kamada et al (1983) [43] | 93.7 | 5:1000 (11/2070) | 0:1000 | 0.0% |
| USA, Fowler et al (1993) [44] | Low incomea | 12:1000 (215/17 163) | 0.9:1000 | 7.4% (16/215) |
| Brazil, Mussi-Pinhata et al [31, 45, 46] | 96.7 | 8:1000 (189/24 095) | 0.9:1000 | 11.1% (12/121) |
| India, Dar et al (2008) [38] | 99.0 | 21:1000 (9/419) | 2.3:1000 | 11.1% (1/9) |
| China, Zhang et al (2007) [47] | 93.1 | 61:1000 (71/1159) | 14.6:1000 | 23.9% (17/71) |
| China, Wang et al (2017) [27] | 96.2% | 7:1000 (75/10 933) | 0.0:1000 | 0.0% |
Abbreviations: cCMV, congenital cytomegalovirus infection; CMV, cytomegalovirus; Ref., reference.
aNot provided.
Congenital CMV Infection Birth Prevalence Rates and Symptomatic Disease Estimates in Neonates Born in Highly Seropositive Populations
| Country, Author(s) (Year) [Ref.] . | Maternal CMV Seroprevalence (%) . | cCMV Infection Birth Prevalence Rate (cCMV/Screened) . | Symptomatic cCMV Prevalence Rate (Symptomatic/Screened) . | Proportion of Symptomatic cCMV . |
|---|---|---|---|---|
| Ivory Coast, Schopfer et al (1978) [32] | 99.7 | 14:1000 (28/2132) | 0:1000 | 0.0% |
| The Gambia, van der Sande et al (2007) [26] | 100.0 | 54:1000 (40/741) | 0:1000 | 0.0% |
| Nigeria, Olusanya et al (2015) [39] | 97.2 | 38:1000 (10/263) | 7.6:1000 | 20.0% (2/10) |
| Israel, Schlesinger et al (2003) [41] | 80.5–85.0 | 7:1000 (14/2000) | 0.5:1000 | 9.0% (1/14) |
| Mexico, Noyola et al (2003) [40] | 91.6 | 9:1000 (5/599) | 0:1000 | 0.0% |
| Japan, Numazaki and Fujikawa (2004) [42] | 85.0 | 3:1000 (37/11 938) | 0.4:1000 | 13.5% (5/37) |
| Japan, Kamada et al (1983) [43] | 93.7 | 5:1000 (11/2070) | 0:1000 | 0.0% |
| USA, Fowler et al (1993) [44] | Low incomea | 12:1000 (215/17 163) | 0.9:1000 | 7.4% (16/215) |
| Brazil, Mussi-Pinhata et al [31, 45, 46] | 96.7 | 8:1000 (189/24 095) | 0.9:1000 | 11.1% (12/121) |
| India, Dar et al (2008) [38] | 99.0 | 21:1000 (9/419) | 2.3:1000 | 11.1% (1/9) |
| China, Zhang et al (2007) [47] | 93.1 | 61:1000 (71/1159) | 14.6:1000 | 23.9% (17/71) |
| China, Wang et al (2017) [27] | 96.2% | 7:1000 (75/10 933) | 0.0:1000 | 0.0% |
| Country, Author(s) (Year) [Ref.] . | Maternal CMV Seroprevalence (%) . | cCMV Infection Birth Prevalence Rate (cCMV/Screened) . | Symptomatic cCMV Prevalence Rate (Symptomatic/Screened) . | Proportion of Symptomatic cCMV . |
|---|---|---|---|---|
| Ivory Coast, Schopfer et al (1978) [32] | 99.7 | 14:1000 (28/2132) | 0:1000 | 0.0% |
| The Gambia, van der Sande et al (2007) [26] | 100.0 | 54:1000 (40/741) | 0:1000 | 0.0% |
| Nigeria, Olusanya et al (2015) [39] | 97.2 | 38:1000 (10/263) | 7.6:1000 | 20.0% (2/10) |
| Israel, Schlesinger et al (2003) [41] | 80.5–85.0 | 7:1000 (14/2000) | 0.5:1000 | 9.0% (1/14) |
| Mexico, Noyola et al (2003) [40] | 91.6 | 9:1000 (5/599) | 0:1000 | 0.0% |
| Japan, Numazaki and Fujikawa (2004) [42] | 85.0 | 3:1000 (37/11 938) | 0.4:1000 | 13.5% (5/37) |
| Japan, Kamada et al (1983) [43] | 93.7 | 5:1000 (11/2070) | 0:1000 | 0.0% |
| USA, Fowler et al (1993) [44] | Low incomea | 12:1000 (215/17 163) | 0.9:1000 | 7.4% (16/215) |
| Brazil, Mussi-Pinhata et al [31, 45, 46] | 96.7 | 8:1000 (189/24 095) | 0.9:1000 | 11.1% (12/121) |
| India, Dar et al (2008) [38] | 99.0 | 21:1000 (9/419) | 2.3:1000 | 11.1% (1/9) |
| China, Zhang et al (2007) [47] | 93.1 | 61:1000 (71/1159) | 14.6:1000 | 23.9% (17/71) |
| China, Wang et al (2017) [27] | 96.2% | 7:1000 (75/10 933) | 0.0:1000 | 0.0% |
Abbreviations: cCMV, congenital cytomegalovirus infection; CMV, cytomegalovirus; Ref., reference.
aNot provided.
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