Table 3.
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LLIN exposure factor analysis using Poisson regression models constructed with % knockdown at 40 min and % mortality at 24 h as dependent variables, and deployment time/damage type as independent variables, Merida, Mexico (n = 5 replicates for each combination deployment time/damage type)

Strain/net exposure factorKnockdownMortality
Mean (95% CI)RR (95% CI)Mean (95% CI)RR (95% CI)
Resistant strain
 Deployment time
  New, nonexposed51.9% (40.4–63.3)157.7% (47.2–68.2)1
   6-mo use24.6% (18.5–30.7)0.47 (0.4–0.5)*29.0% (23.8–34.3)0.50 (0.5–0.6)&
   12-mo use15.3% (11.1–19.5)0.29 (0.3–0.3)*14.8% (10.5–19.1)0.26 (0.2–0.3)*
 Type of damage
  No damage43.6% (28.3–58.9)143.3% (27.3–59.2)1
   Lateral23.5% (13.9–33.0)0.54 (0.5–0.6)*23.1% (14.6–31.6)0.53 (0.5–0.6)*
   Multiple29.4% (16.6–42.2)0.67 (0.6–0.8)*37% (21.3–52.7)0.85 (0.8–0.9)*
   Central26% (16.0–35.9)0.59 (0.5–0.7)*32.1% (23.6–40.5)0.74 (0.7–0.8)*
Susceptible strain
 Deployment time
  New, nonexposed81.3% (73.9–88.7)174.6% (65.3–83.9)1
   6-mo use78.5% (71.6–85.5)0.97 (0.9–1.0)72.3% (64.1–80.5)0.97 (0.9–1.0)
   12-mo use74.3% (62.4–86.4)0.91 (0.8–0.9)*59% (46.7–71.3)0.79 (0.7–0.8)*
 Type of damage
  No damage84.2% (76.9–91.4)179.9% (71.6–88.2)1
  Lateral70.8% (64.9–76.8)0.84 (0.8–0.9)*55% (46.3–63.7)0.69 (0.6–0.7)*
Susceptible strain
  Multiple85.1% (78.4–91.7)1.0 (0.9–1.1)74.3% (64.0–84.5)0.93 (0.9–1.0)
  Central72.1% (55.2–89.1)0.86 (0.8–0.9)*65.4% (48.7–82.0)0.82 (0.7–0.9)*
Strain/net exposure factorKnockdownMortality
Mean (95% CI)RR (95% CI)Mean (95% CI)RR (95% CI)
Resistant strain
 Deployment time
  New, nonexposed51.9% (40.4–63.3)157.7% (47.2–68.2)1
   6-mo use24.6% (18.5–30.7)0.47 (0.4–0.5)*29.0% (23.8–34.3)0.50 (0.5–0.6)&
   12-mo use15.3% (11.1–19.5)0.29 (0.3–0.3)*14.8% (10.5–19.1)0.26 (0.2–0.3)*
 Type of damage
  No damage43.6% (28.3–58.9)143.3% (27.3–59.2)1
   Lateral23.5% (13.9–33.0)0.54 (0.5–0.6)*23.1% (14.6–31.6)0.53 (0.5–0.6)*
   Multiple29.4% (16.6–42.2)0.67 (0.6–0.8)*37% (21.3–52.7)0.85 (0.8–0.9)*
   Central26% (16.0–35.9)0.59 (0.5–0.7)*32.1% (23.6–40.5)0.74 (0.7–0.8)*
Susceptible strain
 Deployment time
  New, nonexposed81.3% (73.9–88.7)174.6% (65.3–83.9)1
   6-mo use78.5% (71.6–85.5)0.97 (0.9–1.0)72.3% (64.1–80.5)0.97 (0.9–1.0)
   12-mo use74.3% (62.4–86.4)0.91 (0.8–0.9)*59% (46.7–71.3)0.79 (0.7–0.8)*
 Type of damage
  No damage84.2% (76.9–91.4)179.9% (71.6–88.2)1
  Lateral70.8% (64.9–76.8)0.84 (0.8–0.9)*55% (46.3–63.7)0.69 (0.6–0.7)*
Susceptible strain
  Multiple85.1% (78.4–91.7)1.0 (0.9–1.1)74.3% (64.0–84.5)0.93 (0.9–1.0)
  Central72.1% (55.2–89.1)0.86 (0.8–0.9)*65.4% (48.7–82.0)0.82 (0.7–0.9)*

RR = rate ratio, estimated with Poisson regression models. CI = confidence interval.

*P < 0.001.

&P = 0.052.

Table 3.
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LLIN exposure factor analysis using Poisson regression models constructed with % knockdown at 40 min and % mortality at 24 h as dependent variables, and deployment time/damage type as independent variables, Merida, Mexico (n = 5 replicates for each combination deployment time/damage type)

Strain/net exposure factorKnockdownMortality
Mean (95% CI)RR (95% CI)Mean (95% CI)RR (95% CI)
Resistant strain
 Deployment time
  New, nonexposed51.9% (40.4–63.3)157.7% (47.2–68.2)1
   6-mo use24.6% (18.5–30.7)0.47 (0.4–0.5)*29.0% (23.8–34.3)0.50 (0.5–0.6)&
   12-mo use15.3% (11.1–19.5)0.29 (0.3–0.3)*14.8% (10.5–19.1)0.26 (0.2–0.3)*
 Type of damage
  No damage43.6% (28.3–58.9)143.3% (27.3–59.2)1
   Lateral23.5% (13.9–33.0)0.54 (0.5–0.6)*23.1% (14.6–31.6)0.53 (0.5–0.6)*
   Multiple29.4% (16.6–42.2)0.67 (0.6–0.8)*37% (21.3–52.7)0.85 (0.8–0.9)*
   Central26% (16.0–35.9)0.59 (0.5–0.7)*32.1% (23.6–40.5)0.74 (0.7–0.8)*
Susceptible strain
 Deployment time
  New, nonexposed81.3% (73.9–88.7)174.6% (65.3–83.9)1
   6-mo use78.5% (71.6–85.5)0.97 (0.9–1.0)72.3% (64.1–80.5)0.97 (0.9–1.0)
   12-mo use74.3% (62.4–86.4)0.91 (0.8–0.9)*59% (46.7–71.3)0.79 (0.7–0.8)*
 Type of damage
  No damage84.2% (76.9–91.4)179.9% (71.6–88.2)1
  Lateral70.8% (64.9–76.8)0.84 (0.8–0.9)*55% (46.3–63.7)0.69 (0.6–0.7)*
Susceptible strain
  Multiple85.1% (78.4–91.7)1.0 (0.9–1.1)74.3% (64.0–84.5)0.93 (0.9–1.0)
  Central72.1% (55.2–89.1)0.86 (0.8–0.9)*65.4% (48.7–82.0)0.82 (0.7–0.9)*
Strain/net exposure factorKnockdownMortality
Mean (95% CI)RR (95% CI)Mean (95% CI)RR (95% CI)
Resistant strain
 Deployment time
  New, nonexposed51.9% (40.4–63.3)157.7% (47.2–68.2)1
   6-mo use24.6% (18.5–30.7)0.47 (0.4–0.5)*29.0% (23.8–34.3)0.50 (0.5–0.6)&
   12-mo use15.3% (11.1–19.5)0.29 (0.3–0.3)*14.8% (10.5–19.1)0.26 (0.2–0.3)*
 Type of damage
  No damage43.6% (28.3–58.9)143.3% (27.3–59.2)1
   Lateral23.5% (13.9–33.0)0.54 (0.5–0.6)*23.1% (14.6–31.6)0.53 (0.5–0.6)*
   Multiple29.4% (16.6–42.2)0.67 (0.6–0.8)*37% (21.3–52.7)0.85 (0.8–0.9)*
   Central26% (16.0–35.9)0.59 (0.5–0.7)*32.1% (23.6–40.5)0.74 (0.7–0.8)*
Susceptible strain
 Deployment time
  New, nonexposed81.3% (73.9–88.7)174.6% (65.3–83.9)1
   6-mo use78.5% (71.6–85.5)0.97 (0.9–1.0)72.3% (64.1–80.5)0.97 (0.9–1.0)
   12-mo use74.3% (62.4–86.4)0.91 (0.8–0.9)*59% (46.7–71.3)0.79 (0.7–0.8)*
 Type of damage
  No damage84.2% (76.9–91.4)179.9% (71.6–88.2)1
  Lateral70.8% (64.9–76.8)0.84 (0.8–0.9)*55% (46.3–63.7)0.69 (0.6–0.7)*
Susceptible strain
  Multiple85.1% (78.4–91.7)1.0 (0.9–1.1)74.3% (64.0–84.5)0.93 (0.9–1.0)
  Central72.1% (55.2–89.1)0.86 (0.8–0.9)*65.4% (48.7–82.0)0.82 (0.7–0.9)*

RR = rate ratio, estimated with Poisson regression models. CI = confidence interval.

*P < 0.001.

&P = 0.052.

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