| Age,a y/Gender . | Initial Antibiotic Treatment . | Modified Antibiotic Treatmentb . | Reason . |
|---|---|---|---|
| 57/M | Clarithromycin + rifampin + ethambutol | Clarithromycin + rifampin + doxycycline | Ethambutol resistant |
| 72/M | Clarithromycin + TMP/SMX + ciprofloxacin | Clarithromycin + TMP/SMX + doxycycline | Fluoroquinolone resistant |
| 86/F | Clarithromycin + levofloxacin | Clarithromycin + rifampin | Fluoroquinolone resistant |
| 77/M | TMP/SMX + levofloxacin | Clarithromycin | Fluoroquinolone resistant, rash with TMP/SMX |
| 74/F | TMP/SMX | Clarithromycin | Better MICs for clarithromycin |
| 43/M | Clarithromycin + moxifloxacin | Clarithromycin + minocycline | Susceptible to moxifloxacin and minocycline, unknown reason |
| 42/M | TMP/SMX + clarithromycin | TMP/SMX | Susceptible to TMP/SMX and clarithromycin, switch to monotherapy, adverse effect with clarithromycin |
| 63/M | Clarithromycin + levofloxacin | Clarithromycin + TMP/SMX | Fluoroquinolone resistant |
| Age,a y/Gender . | Initial Antibiotic Treatment . | Modified Antibiotic Treatmentb . | Reason . |
|---|---|---|---|
| 57/M | Clarithromycin + rifampin + ethambutol | Clarithromycin + rifampin + doxycycline | Ethambutol resistant |
| 72/M | Clarithromycin + TMP/SMX + ciprofloxacin | Clarithromycin + TMP/SMX + doxycycline | Fluoroquinolone resistant |
| 86/F | Clarithromycin + levofloxacin | Clarithromycin + rifampin | Fluoroquinolone resistant |
| 77/M | TMP/SMX + levofloxacin | Clarithromycin | Fluoroquinolone resistant, rash with TMP/SMX |
| 74/F | TMP/SMX | Clarithromycin | Better MICs for clarithromycin |
| 43/M | Clarithromycin + moxifloxacin | Clarithromycin + minocycline | Susceptible to moxifloxacin and minocycline, unknown reason |
| 42/M | TMP/SMX + clarithromycin | TMP/SMX | Susceptible to TMP/SMX and clarithromycin, switch to monotherapy, adverse effect with clarithromycin |
| 63/M | Clarithromycin + levofloxacin | Clarithromycin + TMP/SMX | Fluoroquinolone resistant |
Abbreviations: LFTs, liver function tests; TMP/SMX, trimethoprim and sulfamethoxazole.
aAge at diagnosis.
bBased on susceptibility testing performed using Clinical and Laboratory Standards Institute criteria.
| Age,a y/Gender . | Initial Antibiotic Treatment . | Modified Antibiotic Treatmentb . | Reason . |
|---|---|---|---|
| 57/M | Clarithromycin + rifampin + ethambutol | Clarithromycin + rifampin + doxycycline | Ethambutol resistant |
| 72/M | Clarithromycin + TMP/SMX + ciprofloxacin | Clarithromycin + TMP/SMX + doxycycline | Fluoroquinolone resistant |
| 86/F | Clarithromycin + levofloxacin | Clarithromycin + rifampin | Fluoroquinolone resistant |
| 77/M | TMP/SMX + levofloxacin | Clarithromycin | Fluoroquinolone resistant, rash with TMP/SMX |
| 74/F | TMP/SMX | Clarithromycin | Better MICs for clarithromycin |
| 43/M | Clarithromycin + moxifloxacin | Clarithromycin + minocycline | Susceptible to moxifloxacin and minocycline, unknown reason |
| 42/M | TMP/SMX + clarithromycin | TMP/SMX | Susceptible to TMP/SMX and clarithromycin, switch to monotherapy, adverse effect with clarithromycin |
| 63/M | Clarithromycin + levofloxacin | Clarithromycin + TMP/SMX | Fluoroquinolone resistant |
| Age,a y/Gender . | Initial Antibiotic Treatment . | Modified Antibiotic Treatmentb . | Reason . |
|---|---|---|---|
| 57/M | Clarithromycin + rifampin + ethambutol | Clarithromycin + rifampin + doxycycline | Ethambutol resistant |
| 72/M | Clarithromycin + TMP/SMX + ciprofloxacin | Clarithromycin + TMP/SMX + doxycycline | Fluoroquinolone resistant |
| 86/F | Clarithromycin + levofloxacin | Clarithromycin + rifampin | Fluoroquinolone resistant |
| 77/M | TMP/SMX + levofloxacin | Clarithromycin | Fluoroquinolone resistant, rash with TMP/SMX |
| 74/F | TMP/SMX | Clarithromycin | Better MICs for clarithromycin |
| 43/M | Clarithromycin + moxifloxacin | Clarithromycin + minocycline | Susceptible to moxifloxacin and minocycline, unknown reason |
| 42/M | TMP/SMX + clarithromycin | TMP/SMX | Susceptible to TMP/SMX and clarithromycin, switch to monotherapy, adverse effect with clarithromycin |
| 63/M | Clarithromycin + levofloxacin | Clarithromycin + TMP/SMX | Fluoroquinolone resistant |
Abbreviations: LFTs, liver function tests; TMP/SMX, trimethoprim and sulfamethoxazole.
aAge at diagnosis.
bBased on susceptibility testing performed using Clinical and Laboratory Standards Institute criteria.
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