The approximate and accurate threshold values of –log10(p) simulated for different population sizes
n . | Statistic . | BD . | BH . | QA . | Permutation . | Confidence interval . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
. | . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . |
50 | t | 7.044 | 6.312 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | ||||
U | 6.968 | 6.245 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
|${\chi}^2$| | 7.279 | 6.557 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
p | 7.000 | 6.301 | 6.997 | 6.288 | 7.316 | 6.538 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | |
100 | t | 6.998 | 6.271 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | ||||
U | 6.963 | 6.239 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
|${\chi}^2$| | 7.274 | 6.551 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
p | 7.000 | 6.301 | 6.998 | 6.287 | 7.003 | 6.560 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | |
200 | t | 6.977 | 6.252 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | ||||
U | 6.960 | 6.236 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
|${\chi}^2$| | 7.271 | 6.548 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
p | 7.000 | 6.301 | 6.998 | 6.286 | 7.329 | 6.607 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | |
500 | U | 7.247 | 6.245 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | ||||
|${\chi}^2$| | 7.269 | 6.547 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | |||||
p | 7.000 | 6.301 | 6.995 | 6.288 | 7.329 | 6.445 | 7.311 | 6.224 | (7.070, 7.489) | (6.102, 6.446) | |
1000 | U | 6.958 | 6.323 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | ||||
|${\chi}^2$| | 7.269 | 6.546 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | |||||
p | 7.000 | 6.301 | 6.997 | 6.281 | 7.329 | 6.607 | 6.953 | 6.391 | (6.786, 7.544) | (6.245, 6.691) | |
2000 | U | 6.958 | 6.234 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | ||||
|${\chi}^2$| | 7.268 | 6.546 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | |||||
p | 7.000 | 6.301 | 6.997 | 6.290 | 7.231 | 6.499 | 7.004 | 6.175 | (6.913, 7.232) | (6.042, 6.500) |
n . | Statistic . | BD . | BH . | QA . | Permutation . | Confidence interval . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
. | . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . |
50 | t | 7.044 | 6.312 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | ||||
U | 6.968 | 6.245 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
|${\chi}^2$| | 7.279 | 6.557 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
p | 7.000 | 6.301 | 6.997 | 6.288 | 7.316 | 6.538 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | |
100 | t | 6.998 | 6.271 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | ||||
U | 6.963 | 6.239 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
|${\chi}^2$| | 7.274 | 6.551 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
p | 7.000 | 6.301 | 6.998 | 6.287 | 7.003 | 6.560 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | |
200 | t | 6.977 | 6.252 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | ||||
U | 6.960 | 6.236 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
|${\chi}^2$| | 7.271 | 6.548 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
p | 7.000 | 6.301 | 6.998 | 6.286 | 7.329 | 6.607 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | |
500 | U | 7.247 | 6.245 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | ||||
|${\chi}^2$| | 7.269 | 6.547 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | |||||
p | 7.000 | 6.301 | 6.995 | 6.288 | 7.329 | 6.445 | 7.311 | 6.224 | (7.070, 7.489) | (6.102, 6.446) | |
1000 | U | 6.958 | 6.323 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | ||||
|${\chi}^2$| | 7.269 | 6.546 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | |||||
p | 7.000 | 6.301 | 6.997 | 6.281 | 7.329 | 6.607 | 6.953 | 6.391 | (6.786, 7.544) | (6.245, 6.691) | |
2000 | U | 6.958 | 6.234 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | ||||
|${\chi}^2$| | 7.268 | 6.546 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | |||||
p | 7.000 | 6.301 | 6.997 | 6.290 | 7.231 | 6.499 | 7.004 | 6.175 | (6.913, 7.232) | (6.042, 6.500) |
n is population size; BD represents Bonferroni step-down adjustment, BH controlling FDR and QA quick approximation methods.
The approximate and accurate threshold values of –log10(p) simulated for different population sizes
n . | Statistic . | BD . | BH . | QA . | Permutation . | Confidence interval . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
. | . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . |
50 | t | 7.044 | 6.312 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | ||||
U | 6.968 | 6.245 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
|${\chi}^2$| | 7.279 | 6.557 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
p | 7.000 | 6.301 | 6.997 | 6.288 | 7.316 | 6.538 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | |
100 | t | 6.998 | 6.271 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | ||||
U | 6.963 | 6.239 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
|${\chi}^2$| | 7.274 | 6.551 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
p | 7.000 | 6.301 | 6.998 | 6.287 | 7.003 | 6.560 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | |
200 | t | 6.977 | 6.252 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | ||||
U | 6.960 | 6.236 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
|${\chi}^2$| | 7.271 | 6.548 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
p | 7.000 | 6.301 | 6.998 | 6.286 | 7.329 | 6.607 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | |
500 | U | 7.247 | 6.245 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | ||||
|${\chi}^2$| | 7.269 | 6.547 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | |||||
p | 7.000 | 6.301 | 6.995 | 6.288 | 7.329 | 6.445 | 7.311 | 6.224 | (7.070, 7.489) | (6.102, 6.446) | |
1000 | U | 6.958 | 6.323 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | ||||
|${\chi}^2$| | 7.269 | 6.546 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | |||||
p | 7.000 | 6.301 | 6.997 | 6.281 | 7.329 | 6.607 | 6.953 | 6.391 | (6.786, 7.544) | (6.245, 6.691) | |
2000 | U | 6.958 | 6.234 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | ||||
|${\chi}^2$| | 7.268 | 6.546 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | |||||
p | 7.000 | 6.301 | 6.997 | 6.290 | 7.231 | 6.499 | 7.004 | 6.175 | (6.913, 7.232) | (6.042, 6.500) |
n . | Statistic . | BD . | BH . | QA . | Permutation . | Confidence interval . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
. | . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . | 0.01 . | 0.05 . |
50 | t | 7.044 | 6.312 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | ||||
U | 6.968 | 6.245 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
|${\chi}^2$| | 7.279 | 6.557 | 9.264 | 8.088 | (9.120, 10.001) | (7.738, 8.597) | |||||
p | 7.000 | 6.301 | 6.997 | 6.288 | 7.316 | 6.538 | 6.915 | 6.243 | (6.835, 7.316) | (6.034, 6.539) | |
100 | t | 6.998 | 6.271 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | ||||
U | 6.963 | 6.239 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
|${\chi}^2$| | 7.274 | 6.551 | 7.969 | 7.063 | (7.709, 8.063) | (6.834, 7.475) | |||||
p | 7.000 | 6.301 | 6.998 | 6.287 | 7.003 | 6.560 | 6.934 | 6.245 | (6.738, 7.004) | (6.067, 6.561) | |
200 | t | 6.977 | 6.252 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | ||||
U | 6.960 | 6.236 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
|${\chi}^2$| | 7.271 | 6.548 | 7.309 | 6.677 | (7.237, 7.733) | (6.472, 6.907) | |||||
p | 7.000 | 6.301 | 6.998 | 6.286 | 7.329 | 6.607 | 6.837 | 6.284 | (6.775, 7.204) | (6.104, 6.487) | |
500 | U | 7.247 | 6.245 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | ||||
|${\chi}^2$| | 7.269 | 6.547 | 7.521 | 6.372 | (7.265, 7.710) | (6.245, 6.607) | |||||
p | 7.000 | 6.301 | 6.995 | 6.288 | 7.329 | 6.445 | 7.311 | 6.224 | (7.070, 7.489) | (6.102, 6.446) | |
1000 | U | 6.958 | 6.323 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | ||||
|${\chi}^2$| | 7.269 | 6.546 | 7.046 | 6.468 | (6.874, 7.655) | (6.319, 6.776) | |||||
p | 7.000 | 6.301 | 6.997 | 6.281 | 7.329 | 6.607 | 6.953 | 6.391 | (6.786, 7.544) | (6.245, 6.691) | |
2000 | U | 6.958 | 6.234 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | ||||
|${\chi}^2$| | 7.268 | 6.546 | 7.066 | 6.403 | (6.925, 7.274) | (6.171, 6.637) | |||||
p | 7.000 | 6.301 | 6.997 | 6.290 | 7.231 | 6.499 | 7.004 | 6.175 | (6.913, 7.232) | (6.042, 6.500) |
n is population size; BD represents Bonferroni step-down adjustment, BH controlling FDR and QA quick approximation methods.
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