Table 3.

Predictors of Intramyocardial Lipid Content

Demographic and Traditional CVD Risk ParametersWHIVNon-HIV-Infected WomenWhole Group
Spearman ρP ValueSpearman ρP ValueSpearman ρP Value
Age, y0.260.290.250.450.270.14
Total cholesterol, mg/dL0.100.690.580.060.180.34
LDL-C, mg/dL0.0050.980.670.030.160.40
HDL-C, mg/dL0.400.09−0.450.160.080.69
Triglycerides, mg/dL0.020.920.680.020.350.06
10-Year ASCVD risk score, %0.230.35−0.180.590.200.29
HbA1c, %0.510.03−0.040.910.330.08
BMI, kg/m2−0.010.970.240.510.040.82
WHR0.070.79−0.050.890.110.56
Time since HIV diagnosis, years−0.260.27
Total duration ART, years−0.040.88
CD4+ T cell count, cells/mm30.120.62
HIV viral load, copies/mL0.280.26
Intramyocardial lipid content and reproductive aging status (whole group)
 Reproductive aging groupsIntramyocardial lipid content, %P value
  Group 10.1 (0.1, 1.3)0.02
  Group 20.4 (0.3, 1.2)
  Group 31.1 (0.5, 3.3)
Demographic and Traditional CVD Risk ParametersWHIVNon-HIV-Infected WomenWhole Group
Spearman ρP ValueSpearman ρP ValueSpearman ρP Value
Age, y0.260.290.250.450.270.14
Total cholesterol, mg/dL0.100.690.580.060.180.34
LDL-C, mg/dL0.0050.980.670.030.160.40
HDL-C, mg/dL0.400.09−0.450.160.080.69
Triglycerides, mg/dL0.020.920.680.020.350.06
10-Year ASCVD risk score, %0.230.35−0.180.590.200.29
HbA1c, %0.510.03−0.040.910.330.08
BMI, kg/m2−0.010.970.240.510.040.82
WHR0.070.79−0.050.890.110.56
Time since HIV diagnosis, years−0.260.27
Total duration ART, years−0.040.88
CD4+ T cell count, cells/mm30.120.62
HIV viral load, copies/mL0.280.26
Intramyocardial lipid content and reproductive aging status (whole group)
 Reproductive aging groupsIntramyocardial lipid content, %P value
  Group 10.1 (0.1, 1.3)0.02
  Group 20.4 (0.3, 1.2)
  Group 31.1 (0.5, 3.3)

Spearman ρ is shown for association between intramyocardial triglyceride content (non-normally distributed) and each baseline characteristic within all participants, WHIV, and non-HIV-infected women, respectively.

As shown above, intramyocardial triglyceride content (shown as median IQR) differed significantly across three reproductive aging groups (P = 0.02). P values <0.05 are shown in boldface.

Table 3.

Predictors of Intramyocardial Lipid Content

Demographic and Traditional CVD Risk ParametersWHIVNon-HIV-Infected WomenWhole Group
Spearman ρP ValueSpearman ρP ValueSpearman ρP Value
Age, y0.260.290.250.450.270.14
Total cholesterol, mg/dL0.100.690.580.060.180.34
LDL-C, mg/dL0.0050.980.670.030.160.40
HDL-C, mg/dL0.400.09−0.450.160.080.69
Triglycerides, mg/dL0.020.920.680.020.350.06
10-Year ASCVD risk score, %0.230.35−0.180.590.200.29
HbA1c, %0.510.03−0.040.910.330.08
BMI, kg/m2−0.010.970.240.510.040.82
WHR0.070.79−0.050.890.110.56
Time since HIV diagnosis, years−0.260.27
Total duration ART, years−0.040.88
CD4+ T cell count, cells/mm30.120.62
HIV viral load, copies/mL0.280.26
Intramyocardial lipid content and reproductive aging status (whole group)
 Reproductive aging groupsIntramyocardial lipid content, %P value
  Group 10.1 (0.1, 1.3)0.02
  Group 20.4 (0.3, 1.2)
  Group 31.1 (0.5, 3.3)
Demographic and Traditional CVD Risk ParametersWHIVNon-HIV-Infected WomenWhole Group
Spearman ρP ValueSpearman ρP ValueSpearman ρP Value
Age, y0.260.290.250.450.270.14
Total cholesterol, mg/dL0.100.690.580.060.180.34
LDL-C, mg/dL0.0050.980.670.030.160.40
HDL-C, mg/dL0.400.09−0.450.160.080.69
Triglycerides, mg/dL0.020.920.680.020.350.06
10-Year ASCVD risk score, %0.230.35−0.180.590.200.29
HbA1c, %0.510.03−0.040.910.330.08
BMI, kg/m2−0.010.970.240.510.040.82
WHR0.070.79−0.050.890.110.56
Time since HIV diagnosis, years−0.260.27
Total duration ART, years−0.040.88
CD4+ T cell count, cells/mm30.120.62
HIV viral load, copies/mL0.280.26
Intramyocardial lipid content and reproductive aging status (whole group)
 Reproductive aging groupsIntramyocardial lipid content, %P value
  Group 10.1 (0.1, 1.3)0.02
  Group 20.4 (0.3, 1.2)
  Group 31.1 (0.5, 3.3)

Spearman ρ is shown for association between intramyocardial triglyceride content (non-normally distributed) and each baseline characteristic within all participants, WHIV, and non-HIV-infected women, respectively.

As shown above, intramyocardial triglyceride content (shown as median IQR) differed significantly across three reproductive aging groups (P = 0.02). P values <0.05 are shown in boldface.

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