Table 3 Open in new tab Signatures... | Oxford Academic

Table 3

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Signatures associated with gene age by comparing young genes against old genes

Signature	Young genes	Old genes	Reference
Sequence length	Shorter	Longer	[17]
Intron number	Less	More	[17]
Premature termination codon mutation	More	Less	[36, 40]
Evolution rate	More rapidly	More slowly	[17, 19, 28]
Variable selection pressure	More	Less	[43]
Connections in the interaction network	Less	More	[41, 42]
Essentiality	Less essential	More essential	[44] [45]
Expression	Likely to be lowly expressed	Likely to be highly expressed	[19, 46, 47]
Tissue-specificity	More likely	Less likely	[48]
cis-protein QTLs	More	Less	[49]

Signature	Young genes	Old genes	Reference
Sequence length	Shorter	Longer	[17]
Intron number	Less	More	[17]
Premature termination codon mutation	More	Less	[36, 40]
Evolution rate	More rapidly	More slowly	[17, 19, 28]
Variable selection pressure	More	Less	[43]
Connections in the interaction network	Less	More	[41, 42]
Essentiality	Less essential	More essential	[44] [45]
Expression	Likely to be lowly expressed	Likely to be highly expressed	[19, 46, 47]
Tissue-specificity	More likely	Less likely	[48]
cis-protein QTLs	More	Less	[49]

Abbreviation: QTLs, quantitative trait locis.

Table 3

Open in new tab

Signatures associated with gene age by comparing young genes against old genes

Signature	Young genes	Old genes	Reference
Sequence length	Shorter	Longer	[17]
Intron number	Less	More	[17]
Premature termination codon mutation	More	Less	[36, 40]
Evolution rate	More rapidly	More slowly	[17, 19, 28]
Variable selection pressure	More	Less	[43]
Connections in the interaction network	Less	More	[41, 42]
Essentiality	Less essential	More essential	[44] [45]
Expression	Likely to be lowly expressed	Likely to be highly expressed	[19, 46, 47]
Tissue-specificity	More likely	Less likely	[48]
cis-protein QTLs	More	Less	[49]

Signature	Young genes	Old genes	Reference
Sequence length	Shorter	Longer	[17]
Intron number	Less	More	[17]
Premature termination codon mutation	More	Less	[36, 40]
Evolution rate	More rapidly	More slowly	[17, 19, 28]
Variable selection pressure	More	Less	[43]
Connections in the interaction network	Less	More	[41, 42]
Essentiality	Less essential	More essential	[44] [45]
Expression	Likely to be lowly expressed	Likely to be highly expressed	[19, 46, 47]
Tissue-specificity	More likely	Less likely	[48]
cis-protein QTLs	More	Less	[49]

Abbreviation: QTLs, quantitative trait locis.