Unadjusted and Adjusted 2-way Interactions Between Severe Depression, Alcohol Dependence, and Recreational Drug Use Among Men Who Have Sex With Men
| Exposure . | PR . | (95% CI) . | aPRa . | (95% CI) . |
|---|---|---|---|---|
| Severe depression and alcohol dependence | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.85 | (.59–1.25) | 0.79 | (.55–1.15) |
| Alcohol dependence | 0.50 | (.36–.70) | 0.54 | (.41–.70) |
| Both severe depression and alcohol dependence | 1.19 | (1.00–1.42) | 1.00 | (.83–1.19) |
| P value for interaction | .05 | .97 | ||
| Alcohol dependence and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Alcohol dependence | 0.70 | (.43–1.16) | 0.70 | (.45–1.09) |
| Recreational drug use | 0.63 | (.36–1.12) | 0.63 | (.39–1.03) |
| Both alcohol dependence and recreational drug use | 0.41 | (.14–1.20) | 0.45 | (.20–.99) |
| P value for interaction | .10 | .046 | ||
| Severe depression and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.94 | (.71–1.26) | 0.87 | (.66–1.14) |
| Recreational drug use | 0.61 | (.35–1.05) | 0.62 | (.40–.95) |
| Both severe depression and recreational drug use | 0.39 | (.18–.86) | 0.37 | (.16–.84) |
| P value for interaction | .02 | .02 |
| Exposure . | PR . | (95% CI) . | aPRa . | (95% CI) . |
|---|---|---|---|---|
| Severe depression and alcohol dependence | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.85 | (.59–1.25) | 0.79 | (.55–1.15) |
| Alcohol dependence | 0.50 | (.36–.70) | 0.54 | (.41–.70) |
| Both severe depression and alcohol dependence | 1.19 | (1.00–1.42) | 1.00 | (.83–1.19) |
| P value for interaction | .05 | .97 | ||
| Alcohol dependence and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Alcohol dependence | 0.70 | (.43–1.16) | 0.70 | (.45–1.09) |
| Recreational drug use | 0.63 | (.36–1.12) | 0.63 | (.39–1.03) |
| Both alcohol dependence and recreational drug use | 0.41 | (.14–1.20) | 0.45 | (.20–.99) |
| P value for interaction | .10 | .046 | ||
| Severe depression and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.94 | (.71–1.26) | 0.87 | (.66–1.14) |
| Recreational drug use | 0.61 | (.35–1.05) | 0.62 | (.40–.95) |
| Both severe depression and recreational drug use | 0.39 | (.18–.86) | 0.37 | (.16–.84) |
| P value for interaction | .02 | .02 |
With Respondent-driven Sampling II weights.
Abbreviations: aPR, adjusted prevalence ratio; CI, confidence interval; PR, prevalence ratio; Ref, reference value.
aAdjusted for age, sexual identity, and human immunodeficiency virus treatment literacy.
Unadjusted and Adjusted 2-way Interactions Between Severe Depression, Alcohol Dependence, and Recreational Drug Use Among Men Who Have Sex With Men
| Exposure . | PR . | (95% CI) . | aPRa . | (95% CI) . |
|---|---|---|---|---|
| Severe depression and alcohol dependence | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.85 | (.59–1.25) | 0.79 | (.55–1.15) |
| Alcohol dependence | 0.50 | (.36–.70) | 0.54 | (.41–.70) |
| Both severe depression and alcohol dependence | 1.19 | (1.00–1.42) | 1.00 | (.83–1.19) |
| P value for interaction | .05 | .97 | ||
| Alcohol dependence and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Alcohol dependence | 0.70 | (.43–1.16) | 0.70 | (.45–1.09) |
| Recreational drug use | 0.63 | (.36–1.12) | 0.63 | (.39–1.03) |
| Both alcohol dependence and recreational drug use | 0.41 | (.14–1.20) | 0.45 | (.20–.99) |
| P value for interaction | .10 | .046 | ||
| Severe depression and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.94 | (.71–1.26) | 0.87 | (.66–1.14) |
| Recreational drug use | 0.61 | (.35–1.05) | 0.62 | (.40–.95) |
| Both severe depression and recreational drug use | 0.39 | (.18–.86) | 0.37 | (.16–.84) |
| P value for interaction | .02 | .02 |
| Exposure . | PR . | (95% CI) . | aPRa . | (95% CI) . |
|---|---|---|---|---|
| Severe depression and alcohol dependence | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.85 | (.59–1.25) | 0.79 | (.55–1.15) |
| Alcohol dependence | 0.50 | (.36–.70) | 0.54 | (.41–.70) |
| Both severe depression and alcohol dependence | 1.19 | (1.00–1.42) | 1.00 | (.83–1.19) |
| P value for interaction | .05 | .97 | ||
| Alcohol dependence and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Alcohol dependence | 0.70 | (.43–1.16) | 0.70 | (.45–1.09) |
| Recreational drug use | 0.63 | (.36–1.12) | 0.63 | (.39–1.03) |
| Both alcohol dependence and recreational drug use | 0.41 | (.14–1.20) | 0.45 | (.20–.99) |
| P value for interaction | .10 | .046 | ||
| Severe depression and recreational drug use | ||||
| Neither | Ref | Ref | ||
| Severe depression | 0.94 | (.71–1.26) | 0.87 | (.66–1.14) |
| Recreational drug use | 0.61 | (.35–1.05) | 0.62 | (.40–.95) |
| Both severe depression and recreational drug use | 0.39 | (.18–.86) | 0.37 | (.16–.84) |
| P value for interaction | .02 | .02 |
With Respondent-driven Sampling II weights.
Abbreviations: aPR, adjusted prevalence ratio; CI, confidence interval; PR, prevalence ratio; Ref, reference value.
aAdjusted for age, sexual identity, and human immunodeficiency virus treatment literacy.
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