Association Between Detection of Specific Vaginal Bacteria Using Targeted Quantitative Polymerase Chain Reaction Analysis and the First Incident Trichomonas vaginalis (TV) Infection in 18 Women Who Acquired TV (Cases) and 36 Matched Women Who Remained Uninfected (Controls)
| Bacterial taxon . | Cases (n = 18) . | Controls (n = 36) . | RR (95% CI) . | P . | Adjusted RR (95% CI)a . | Pb . |
|---|---|---|---|---|---|---|
| BVAB1 | 5 (28) | 1 (3) | 3.69 (2.32–5.87) | <.001 | 3.33 (1.96–5.67) | .005 |
| Mageeibacillus indolicus (BVAB3) | 9 (50) | 10 (28) | 1.79 (.86–3.73) | .12 | 1.48 (.66–3.33) | .34 |
| Prevotella amnii | 12 (67) | 8 (22) | 3.30 (1.47–7.40) | .004 | 3.13 (1.34–7.32) | .003 |
| Prevotella speciesc | 12 (67) | 13 (37) | 2.24 (.99–5.08) | .053 | 2.01 (.84–4.83) | .12 |
| Dialister propionicifaciens | 14 (78) | 19 (53) | 2.12 (.81–5.55) | .13 | 1.94 (.74–5.04) | .18 |
| Lactobacillus crispatus | 4 (22) | 10 (28) | 0.80 (.32–2.01) | .63 | 0.80 (.32–1.98) | .62 |
| Sneathia sanguinegens | 14 (78) | 14 (39) | 3.13 (1.18–8.26) | .02 | 2.89 (1.05–7.96) | .04 |
| Sneathia species | 15 (83) | 18 (50) | 3.03 (1.00–9.18) | .05 | 2.69 (.84–8.58) | .10 |
| Bacterial taxon . | Cases (n = 18) . | Controls (n = 36) . | RR (95% CI) . | P . | Adjusted RR (95% CI)a . | Pb . |
|---|---|---|---|---|---|---|
| BVAB1 | 5 (28) | 1 (3) | 3.69 (2.32–5.87) | <.001 | 3.33 (1.96–5.67) | .005 |
| Mageeibacillus indolicus (BVAB3) | 9 (50) | 10 (28) | 1.79 (.86–3.73) | .12 | 1.48 (.66–3.33) | .34 |
| Prevotella amnii | 12 (67) | 8 (22) | 3.30 (1.47–7.40) | .004 | 3.13 (1.34–7.32) | .003 |
| Prevotella speciesc | 12 (67) | 13 (37) | 2.24 (.99–5.08) | .053 | 2.01 (.84–4.83) | .12 |
| Dialister propionicifaciens | 14 (78) | 19 (53) | 2.12 (.81–5.55) | .13 | 1.94 (.74–5.04) | .18 |
| Lactobacillus crispatus | 4 (22) | 10 (28) | 0.80 (.32–2.01) | .63 | 0.80 (.32–1.98) | .62 |
| Sneathia sanguinegens | 14 (78) | 14 (39) | 3.13 (1.18–8.26) | .02 | 2.89 (1.05–7.96) | .04 |
| Sneathia species | 15 (83) | 18 (50) | 3.03 (1.00–9.18) | .05 | 2.69 (.84–8.58) | .10 |
Data are mean ± SD or no. (%) of participants, unless otherwise indicated.
Abbreviations: BVAB, bacterial vaginosis–associated bacterium; CI, confidence interval; RR, risk ratio.
aAdjusted for menstrual phase.
bValues <.05 are considered statistically significant.
cPrevotella species were present in almost all samples, so values for cases and controls represent proportions of samples with a Prevotella 16S ribosomal RNA concentration at or above the median detected concentration of 6.9 copies/mL.
Association Between Detection of Specific Vaginal Bacteria Using Targeted Quantitative Polymerase Chain Reaction Analysis and the First Incident Trichomonas vaginalis (TV) Infection in 18 Women Who Acquired TV (Cases) and 36 Matched Women Who Remained Uninfected (Controls)
| Bacterial taxon . | Cases (n = 18) . | Controls (n = 36) . | RR (95% CI) . | P . | Adjusted RR (95% CI)a . | Pb . |
|---|---|---|---|---|---|---|
| BVAB1 | 5 (28) | 1 (3) | 3.69 (2.32–5.87) | <.001 | 3.33 (1.96–5.67) | .005 |
| Mageeibacillus indolicus (BVAB3) | 9 (50) | 10 (28) | 1.79 (.86–3.73) | .12 | 1.48 (.66–3.33) | .34 |
| Prevotella amnii | 12 (67) | 8 (22) | 3.30 (1.47–7.40) | .004 | 3.13 (1.34–7.32) | .003 |
| Prevotella speciesc | 12 (67) | 13 (37) | 2.24 (.99–5.08) | .053 | 2.01 (.84–4.83) | .12 |
| Dialister propionicifaciens | 14 (78) | 19 (53) | 2.12 (.81–5.55) | .13 | 1.94 (.74–5.04) | .18 |
| Lactobacillus crispatus | 4 (22) | 10 (28) | 0.80 (.32–2.01) | .63 | 0.80 (.32–1.98) | .62 |
| Sneathia sanguinegens | 14 (78) | 14 (39) | 3.13 (1.18–8.26) | .02 | 2.89 (1.05–7.96) | .04 |
| Sneathia species | 15 (83) | 18 (50) | 3.03 (1.00–9.18) | .05 | 2.69 (.84–8.58) | .10 |
| Bacterial taxon . | Cases (n = 18) . | Controls (n = 36) . | RR (95% CI) . | P . | Adjusted RR (95% CI)a . | Pb . |
|---|---|---|---|---|---|---|
| BVAB1 | 5 (28) | 1 (3) | 3.69 (2.32–5.87) | <.001 | 3.33 (1.96–5.67) | .005 |
| Mageeibacillus indolicus (BVAB3) | 9 (50) | 10 (28) | 1.79 (.86–3.73) | .12 | 1.48 (.66–3.33) | .34 |
| Prevotella amnii | 12 (67) | 8 (22) | 3.30 (1.47–7.40) | .004 | 3.13 (1.34–7.32) | .003 |
| Prevotella speciesc | 12 (67) | 13 (37) | 2.24 (.99–5.08) | .053 | 2.01 (.84–4.83) | .12 |
| Dialister propionicifaciens | 14 (78) | 19 (53) | 2.12 (.81–5.55) | .13 | 1.94 (.74–5.04) | .18 |
| Lactobacillus crispatus | 4 (22) | 10 (28) | 0.80 (.32–2.01) | .63 | 0.80 (.32–1.98) | .62 |
| Sneathia sanguinegens | 14 (78) | 14 (39) | 3.13 (1.18–8.26) | .02 | 2.89 (1.05–7.96) | .04 |
| Sneathia species | 15 (83) | 18 (50) | 3.03 (1.00–9.18) | .05 | 2.69 (.84–8.58) | .10 |
Data are mean ± SD or no. (%) of participants, unless otherwise indicated.
Abbreviations: BVAB, bacterial vaginosis–associated bacterium; CI, confidence interval; RR, risk ratio.
aAdjusted for menstrual phase.
bValues <.05 are considered statistically significant.
cPrevotella species were present in almost all samples, so values for cases and controls represent proportions of samples with a Prevotella 16S ribosomal RNA concentration at or above the median detected concentration of 6.9 copies/mL.
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