Table 3 Open in new tab Multivariable...

Table 3

Multivariable analysis for OS in patients who underwent salvage radiotherapy (n = 115)

Variable	Hazard Ratio	95% CI	P-value
Age (continuous)	1.005	0.98–1.03	0.63
RPA class
Class 1	Reference		0.63
Class 2	0.88	0.56–1.39	0.59
Class 3	1.53	0.4–5.91	0.54
Pattern of initial LMD
Nodular (vs classical)	0.59	0.34–0.98	0.04
Primary tumor type
NSCLC	Reference		0.002
Breast	0.69	0.36–1.32	0.26
Melanoma	2.4	1.12–5.17	0.03
Gastrointestinal	1.47	0.75–2.91	0.26
Other	0.42	0.18–1.01	0.054
Type of RT salvage
Focal RT (vs WBRT)	0.65	0.4–1.06	0.09
Number of BM at initial SRS
1	Reference		0.91
2–4	0.91	0.55–1.5	0.71
≥5	1.07	0.41–2.78	0.89

Variable	Hazard Ratio	95% CI	P-value
Age (continuous)	1.005	0.98–1.03	0.63
RPA class
Class 1	Reference		0.63
Class 2	0.88	0.56–1.39	0.59
Class 3	1.53	0.4–5.91	0.54
Pattern of initial LMD
Nodular (vs classical)	0.59	0.34–0.98	0.04
Primary tumor type
NSCLC	Reference		0.002
Breast	0.69	0.36–1.32	0.26
Melanoma	2.4	1.12–5.17	0.03
Gastrointestinal	1.47	0.75–2.91	0.26
Other	0.42	0.18–1.01	0.054
Type of RT salvage
Focal RT (vs WBRT)	0.65	0.4–1.06	0.09
Number of BM at initial SRS
1	Reference		0.91
2–4	0.91	0.55–1.5	0.71
≥5	1.07	0.41–2.78	0.89