Recommendations for the evaluation of myocardial recovery
| Recommendations | Class | Level | References |
| Pathological evaluation of myocardial tissue obtained during apical coring to identify treatable aetiologies of heart failure is recommended. | I | C | [410, 411] |
| In patients with LT-MCS with non-ischaemic cardiomyopathy, optimized medical heart failure therapy to promote myocardial recovery is recommended. | I | C | [405] |
| Adding a selective beta-2 adrenergic agonist to conventional HF therapy is not recommended. | III | B | |
| Routine screening of patients with LT-MCS with non-ischaemic cardiomyopathy for myocardial recovery by echocardiography, including the ramp test, is recommended. | I | B | [397, 412] |
| Before explantation, invasive haemodynamic examination of patients with LT-MCS is recommended. | I | B | [398] |
| Cardiopulmonary exercise testing may be considered prior to the decision about LT-MCS explantation. | IIb | C | [413] |
| Screening for recurrence of heart failure after LT-MCS explantation is recommended. | I | C | [414, 415] |
| Recommendations | Class | Level | References |
| Pathological evaluation of myocardial tissue obtained during apical coring to identify treatable aetiologies of heart failure is recommended. | I | C | [410, 411] |
| In patients with LT-MCS with non-ischaemic cardiomyopathy, optimized medical heart failure therapy to promote myocardial recovery is recommended. | I | C | [405] |
| Adding a selective beta-2 adrenergic agonist to conventional HF therapy is not recommended. | III | B | |
| Routine screening of patients with LT-MCS with non-ischaemic cardiomyopathy for myocardial recovery by echocardiography, including the ramp test, is recommended. | I | B | [397, 412] |
| Before explantation, invasive haemodynamic examination of patients with LT-MCS is recommended. | I | B | [398] |
| Cardiopulmonary exercise testing may be considered prior to the decision about LT-MCS explantation. | IIb | C | [413] |
| Screening for recurrence of heart failure after LT-MCS explantation is recommended. | I | C | [414, 415] |
LT-MCS: long-term mechanical circulatory support.
Recommendations for the evaluation of myocardial recovery
| Recommendations | Class | Level | References |
| Pathological evaluation of myocardial tissue obtained during apical coring to identify treatable aetiologies of heart failure is recommended. | I | C | [410, 411] |
| In patients with LT-MCS with non-ischaemic cardiomyopathy, optimized medical heart failure therapy to promote myocardial recovery is recommended. | I | C | [405] |
| Adding a selective beta-2 adrenergic agonist to conventional HF therapy is not recommended. | III | B | |
| Routine screening of patients with LT-MCS with non-ischaemic cardiomyopathy for myocardial recovery by echocardiography, including the ramp test, is recommended. | I | B | [397, 412] |
| Before explantation, invasive haemodynamic examination of patients with LT-MCS is recommended. | I | B | [398] |
| Cardiopulmonary exercise testing may be considered prior to the decision about LT-MCS explantation. | IIb | C | [413] |
| Screening for recurrence of heart failure after LT-MCS explantation is recommended. | I | C | [414, 415] |
| Recommendations | Class | Level | References |
| Pathological evaluation of myocardial tissue obtained during apical coring to identify treatable aetiologies of heart failure is recommended. | I | C | [410, 411] |
| In patients with LT-MCS with non-ischaemic cardiomyopathy, optimized medical heart failure therapy to promote myocardial recovery is recommended. | I | C | [405] |
| Adding a selective beta-2 adrenergic agonist to conventional HF therapy is not recommended. | III | B | |
| Routine screening of patients with LT-MCS with non-ischaemic cardiomyopathy for myocardial recovery by echocardiography, including the ramp test, is recommended. | I | B | [397, 412] |
| Before explantation, invasive haemodynamic examination of patients with LT-MCS is recommended. | I | B | [398] |
| Cardiopulmonary exercise testing may be considered prior to the decision about LT-MCS explantation. | IIb | C | [413] |
| Screening for recurrence of heart failure after LT-MCS explantation is recommended. | I | C | [414, 415] |
LT-MCS: long-term mechanical circulatory support.
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