Table 1

Baseline characteristics of patients by hospitalization status

CharacteristicsHospitalized (N = 7200)Not hospitalized (N = 10 913)P-valueaCardiovascular hospitalized (N = 2920)
Age (years) (SD)72.5 (8.4)70.8 (8.8)<0.000171.8 (8.7)
BMI (kg/m2), N (%)<0.0001
 <251801 (25.0)2896 (26.6)675 (23.1)
 25–302757 (38.3)4354 (40.0)1153 (39.5)
 30–351657 (23.0)2381 (21.9)689 (23.6)
 ≥35976 (13.6)1265 (11.6)400 (13.7)
Male gender, N (%)4517 (62.7)6997 (64.1)0.061804 (61.8)
Type of atrial fibrillation, N (%)<0.0001
 Paroxysmal2602 (36.1)3341 (30.6)1173 (40.2)
 Persistent2271 (31.5)3518 (32.3)907 (31.1)
 Permanent2326 (32.3)4049 (37.1)840 (28.8)
CHADS2 score, N (%)<0.0001
 0 or 11966 (27.3)3817 (35.0)754 (25.8)
 22549 (35.4)3904 (35.8)1059 (36.3)
 ≥32685 (37.3)3191 (29.2)1107 (37.9)
Previous stroke or TIA or systemic embolic event, N (%)1636 (22.7)2317 (21.2)0.02646 (22.1)
Prior myocardial infarction or CAD, N (%)2673 (37.1)2977 (27.3)<0.00011218 (41.7)
History of heart failure, N (%)2494 (34.6)3299 (30.2)<0.00011137 (38.9)
Diabetes mellitus, N (%)1940 (26.9)2281 (20.9)<0.0001832 (28.5)
Hypertension, N (%)5763 (80.0)8520 (78.1)0.0012363 (80.9)
Valvular heart disease, N (%)1728 (24.0)2216 (20.3)<0.0001719 (24.6)
CrCl ≤50 mL/min, N (%)1658 (23.2)1896 (17.5)<0.0001654 (22.6)
Cancer at baseline, N (%)889 (12.3)996 (9.1)<0.0001348 (11.9)
CharacteristicsHospitalized (N = 7200)Not hospitalized (N = 10 913)P-valueaCardiovascular hospitalized (N = 2920)
Age (years) (SD)72.5 (8.4)70.8 (8.8)<0.000171.8 (8.7)
BMI (kg/m2), N (%)<0.0001
 <251801 (25.0)2896 (26.6)675 (23.1)
 25–302757 (38.3)4354 (40.0)1153 (39.5)
 30–351657 (23.0)2381 (21.9)689 (23.6)
 ≥35976 (13.6)1265 (11.6)400 (13.7)
Male gender, N (%)4517 (62.7)6997 (64.1)0.061804 (61.8)
Type of atrial fibrillation, N (%)<0.0001
 Paroxysmal2602 (36.1)3341 (30.6)1173 (40.2)
 Persistent2271 (31.5)3518 (32.3)907 (31.1)
 Permanent2326 (32.3)4049 (37.1)840 (28.8)
CHADS2 score, N (%)<0.0001
 0 or 11966 (27.3)3817 (35.0)754 (25.8)
 22549 (35.4)3904 (35.8)1059 (36.3)
 ≥32685 (37.3)3191 (29.2)1107 (37.9)
Previous stroke or TIA or systemic embolic event, N (%)1636 (22.7)2317 (21.2)0.02646 (22.1)
Prior myocardial infarction or CAD, N (%)2673 (37.1)2977 (27.3)<0.00011218 (41.7)
History of heart failure, N (%)2494 (34.6)3299 (30.2)<0.00011137 (38.9)
Diabetes mellitus, N (%)1940 (26.9)2281 (20.9)<0.0001832 (28.5)
Hypertension, N (%)5763 (80.0)8520 (78.1)0.0012363 (80.9)
Valvular heart disease, N (%)1728 (24.0)2216 (20.3)<0.0001719 (24.6)
CrCl ≤50 mL/min, N (%)1658 (23.2)1896 (17.5)<0.0001654 (22.6)
Cancer at baseline, N (%)889 (12.3)996 (9.1)<0.0001348 (11.9)

Missing data: CHADS2 score data missing in one patient and CrCl <50 data missing in 162 patients.

BMI, body mass index; CAD, coronary artery disease; CrCl, creatinine clearance; SD, standard deviation; TIA, transient ischaemic attack.

a

P-value (from Fisher’s exact test for binary data, t-test for continuous data, or χ2 test for categorical data) reported compares patients hospitalized compared with non-hospitalized patients.

Table 1

Baseline characteristics of patients by hospitalization status

CharacteristicsHospitalized (N = 7200)Not hospitalized (N = 10 913)P-valueaCardiovascular hospitalized (N = 2920)
Age (years) (SD)72.5 (8.4)70.8 (8.8)<0.000171.8 (8.7)
BMI (kg/m2), N (%)<0.0001
 <251801 (25.0)2896 (26.6)675 (23.1)
 25–302757 (38.3)4354 (40.0)1153 (39.5)
 30–351657 (23.0)2381 (21.9)689 (23.6)
 ≥35976 (13.6)1265 (11.6)400 (13.7)
Male gender, N (%)4517 (62.7)6997 (64.1)0.061804 (61.8)
Type of atrial fibrillation, N (%)<0.0001
 Paroxysmal2602 (36.1)3341 (30.6)1173 (40.2)
 Persistent2271 (31.5)3518 (32.3)907 (31.1)
 Permanent2326 (32.3)4049 (37.1)840 (28.8)
CHADS2 score, N (%)<0.0001
 0 or 11966 (27.3)3817 (35.0)754 (25.8)
 22549 (35.4)3904 (35.8)1059 (36.3)
 ≥32685 (37.3)3191 (29.2)1107 (37.9)
Previous stroke or TIA or systemic embolic event, N (%)1636 (22.7)2317 (21.2)0.02646 (22.1)
Prior myocardial infarction or CAD, N (%)2673 (37.1)2977 (27.3)<0.00011218 (41.7)
History of heart failure, N (%)2494 (34.6)3299 (30.2)<0.00011137 (38.9)
Diabetes mellitus, N (%)1940 (26.9)2281 (20.9)<0.0001832 (28.5)
Hypertension, N (%)5763 (80.0)8520 (78.1)0.0012363 (80.9)
Valvular heart disease, N (%)1728 (24.0)2216 (20.3)<0.0001719 (24.6)
CrCl ≤50 mL/min, N (%)1658 (23.2)1896 (17.5)<0.0001654 (22.6)
Cancer at baseline, N (%)889 (12.3)996 (9.1)<0.0001348 (11.9)
CharacteristicsHospitalized (N = 7200)Not hospitalized (N = 10 913)P-valueaCardiovascular hospitalized (N = 2920)
Age (years) (SD)72.5 (8.4)70.8 (8.8)<0.000171.8 (8.7)
BMI (kg/m2), N (%)<0.0001
 <251801 (25.0)2896 (26.6)675 (23.1)
 25–302757 (38.3)4354 (40.0)1153 (39.5)
 30–351657 (23.0)2381 (21.9)689 (23.6)
 ≥35976 (13.6)1265 (11.6)400 (13.7)
Male gender, N (%)4517 (62.7)6997 (64.1)0.061804 (61.8)
Type of atrial fibrillation, N (%)<0.0001
 Paroxysmal2602 (36.1)3341 (30.6)1173 (40.2)
 Persistent2271 (31.5)3518 (32.3)907 (31.1)
 Permanent2326 (32.3)4049 (37.1)840 (28.8)
CHADS2 score, N (%)<0.0001
 0 or 11966 (27.3)3817 (35.0)754 (25.8)
 22549 (35.4)3904 (35.8)1059 (36.3)
 ≥32685 (37.3)3191 (29.2)1107 (37.9)
Previous stroke or TIA or systemic embolic event, N (%)1636 (22.7)2317 (21.2)0.02646 (22.1)
Prior myocardial infarction or CAD, N (%)2673 (37.1)2977 (27.3)<0.00011218 (41.7)
History of heart failure, N (%)2494 (34.6)3299 (30.2)<0.00011137 (38.9)
Diabetes mellitus, N (%)1940 (26.9)2281 (20.9)<0.0001832 (28.5)
Hypertension, N (%)5763 (80.0)8520 (78.1)0.0012363 (80.9)
Valvular heart disease, N (%)1728 (24.0)2216 (20.3)<0.0001719 (24.6)
CrCl ≤50 mL/min, N (%)1658 (23.2)1896 (17.5)<0.0001654 (22.6)
Cancer at baseline, N (%)889 (12.3)996 (9.1)<0.0001348 (11.9)

Missing data: CHADS2 score data missing in one patient and CrCl <50 data missing in 162 patients.

BMI, body mass index; CAD, coronary artery disease; CrCl, creatinine clearance; SD, standard deviation; TIA, transient ischaemic attack.

a

P-value (from Fisher’s exact test for binary data, t-test for continuous data, or χ2 test for categorical data) reported compares patients hospitalized compared with non-hospitalized patients.

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