| . | Baseline . | 1 y . | 2 y . | 3 y . | 4 y . | 5 y . | 6 y . | 7 y . | 8 y . |
|---|---|---|---|---|---|---|---|---|---|
| PF | 72.3 ± 4.5 | 76.5 ± 5.4 | 81.8 ± 3.8a | 76.5 ± 5 | 76.3 ± 5.2 | 79.5 ± 4.8 | 80.3 ± 4.3 | 74.8 ± 6.2 | 73 ± 6.3 |
| RF | 52.5 ± 8.1 | 62.5 ± 8.6 | 65 ± 8.6 | 68.8 ± 7.8 | 73.8 ± 7.9a | 70 ± 8.4 | 62.5 ± 8.4 | 61.3 ± 8.6 | 61.3 ± 9.7 |
| RE | 63.3 ± 9.6 | 80 ± 6.6 | 73.3 ± 8.6 | 70 ± 9 | 71.66 ± 8.1 | 83.3 ± 6.6a | 71.7 ± 8.4 | 76.6 ± 7.7 | 71.7 ± 8.8a |
| VT | 35 ± 5 | 50.5 ± 4.8b | 49.3 ± 4.2b | 48.8 ± 4.3b | 49 ± 4.3b | 50.3 ± 5.1b | 48 ± 5.4b | 46.3 ± 5.7b | 45.3 ± 5.6a |
| MH | 60 ± 4.4 | 71.4 ± 4.1b | 70.4 ± 3.8b | 73.2 ± 3.4b | 66 ± 4.3 | 71.4 ± 3.9b | 70.4 ± 4.3b | 69.8 ± 3.92a | 71.2 ± 4b |
| SF | 63.1 ± 5.3 | 75.6 ± 4.9b | 71.9 ± 4.9 | 75.6 ± 4.7b | 72.4 ± 6.0a | 80 ± 5.6b | 75 ± 5.7a | 80.6 ± 5.6b | 78.1 ± 5.2b |
| BP | 55.1 ± 5 | 65.1 ± 5a | 74.5 ± 4.1b | 69.8 ± 5.9b | 66.1 ± 5.4a | 70.3 ± 5.9b | 68.1 ± 5.6b | 64.5 ± 6a | 66.9 ± 6.3a |
| GH | 48.5 ± 4.3 | 64.3 ± 4.7b | 62.5 ± 4.1b | 61.8 ± 4.2b | 58.3 ± 4.5b | 61.5 ± 4.2b | 60.8 ± 5b | 58.8 ± 3.9b | 57.5 ± 4.7b |
| PCS | 228.4 ± 16.3 | 265.4 ± 19.6a | 283.8 ± 16.2b | 276.8 ± 18b | 274.4 ± 16.5b | 281.3 ± 19.4b | 271.6 ± 20.3b | 259.3 ± 19.7 | 258.6 ± 22.1 |
| MCS | 221.5 ± 18.2 | 275 ± 14.7b | 264.8 ± 16.6a | 267.5 ± 16.7b | 259 ± 20a | 285 ± 16.3b | 270 ± 20.7b | 273.3 ± 19.6b | 266.2 ± 19b |
| . | Baseline . | 1 y . | 2 y . | 3 y . | 4 y . | 5 y . | 6 y . | 7 y . | 8 y . |
|---|---|---|---|---|---|---|---|---|---|
| PF | 72.3 ± 4.5 | 76.5 ± 5.4 | 81.8 ± 3.8a | 76.5 ± 5 | 76.3 ± 5.2 | 79.5 ± 4.8 | 80.3 ± 4.3 | 74.8 ± 6.2 | 73 ± 6.3 |
| RF | 52.5 ± 8.1 | 62.5 ± 8.6 | 65 ± 8.6 | 68.8 ± 7.8 | 73.8 ± 7.9a | 70 ± 8.4 | 62.5 ± 8.4 | 61.3 ± 8.6 | 61.3 ± 9.7 |
| RE | 63.3 ± 9.6 | 80 ± 6.6 | 73.3 ± 8.6 | 70 ± 9 | 71.66 ± 8.1 | 83.3 ± 6.6a | 71.7 ± 8.4 | 76.6 ± 7.7 | 71.7 ± 8.8a |
| VT | 35 ± 5 | 50.5 ± 4.8b | 49.3 ± 4.2b | 48.8 ± 4.3b | 49 ± 4.3b | 50.3 ± 5.1b | 48 ± 5.4b | 46.3 ± 5.7b | 45.3 ± 5.6a |
| MH | 60 ± 4.4 | 71.4 ± 4.1b | 70.4 ± 3.8b | 73.2 ± 3.4b | 66 ± 4.3 | 71.4 ± 3.9b | 70.4 ± 4.3b | 69.8 ± 3.92a | 71.2 ± 4b |
| SF | 63.1 ± 5.3 | 75.6 ± 4.9b | 71.9 ± 4.9 | 75.6 ± 4.7b | 72.4 ± 6.0a | 80 ± 5.6b | 75 ± 5.7a | 80.6 ± 5.6b | 78.1 ± 5.2b |
| BP | 55.1 ± 5 | 65.1 ± 5a | 74.5 ± 4.1b | 69.8 ± 5.9b | 66.1 ± 5.4a | 70.3 ± 5.9b | 68.1 ± 5.6b | 64.5 ± 6a | 66.9 ± 6.3a |
| GH | 48.5 ± 4.3 | 64.3 ± 4.7b | 62.5 ± 4.1b | 61.8 ± 4.2b | 58.3 ± 4.5b | 61.5 ± 4.2b | 60.8 ± 5b | 58.8 ± 3.9b | 57.5 ± 4.7b |
| PCS | 228.4 ± 16.3 | 265.4 ± 19.6a | 283.8 ± 16.2b | 276.8 ± 18b | 274.4 ± 16.5b | 281.3 ± 19.4b | 271.6 ± 20.3b | 259.3 ± 19.7 | 258.6 ± 22.1 |
| MCS | 221.5 ± 18.2 | 275 ± 14.7b | 264.8 ± 16.6a | 267.5 ± 16.7b | 259 ± 20a | 285 ± 16.3b | 270 ± 20.7b | 273.3 ± 19.6b | 266.2 ± 19b |
| . | Baseline . | 1 y . | 2 y . | 3 y . | 4 y . | 5 y . | 6 y . | 7 y . | 8 y . |
|---|---|---|---|---|---|---|---|---|---|
| PF | 72.3 ± 4.5 | 76.5 ± 5.4 | 81.8 ± 3.8a | 76.5 ± 5 | 76.3 ± 5.2 | 79.5 ± 4.8 | 80.3 ± 4.3 | 74.8 ± 6.2 | 73 ± 6.3 |
| RF | 52.5 ± 8.1 | 62.5 ± 8.6 | 65 ± 8.6 | 68.8 ± 7.8 | 73.8 ± 7.9a | 70 ± 8.4 | 62.5 ± 8.4 | 61.3 ± 8.6 | 61.3 ± 9.7 |
| RE | 63.3 ± 9.6 | 80 ± 6.6 | 73.3 ± 8.6 | 70 ± 9 | 71.66 ± 8.1 | 83.3 ± 6.6a | 71.7 ± 8.4 | 76.6 ± 7.7 | 71.7 ± 8.8a |
| VT | 35 ± 5 | 50.5 ± 4.8b | 49.3 ± 4.2b | 48.8 ± 4.3b | 49 ± 4.3b | 50.3 ± 5.1b | 48 ± 5.4b | 46.3 ± 5.7b | 45.3 ± 5.6a |
| MH | 60 ± 4.4 | 71.4 ± 4.1b | 70.4 ± 3.8b | 73.2 ± 3.4b | 66 ± 4.3 | 71.4 ± 3.9b | 70.4 ± 4.3b | 69.8 ± 3.92a | 71.2 ± 4b |
| SF | 63.1 ± 5.3 | 75.6 ± 4.9b | 71.9 ± 4.9 | 75.6 ± 4.7b | 72.4 ± 6.0a | 80 ± 5.6b | 75 ± 5.7a | 80.6 ± 5.6b | 78.1 ± 5.2b |
| BP | 55.1 ± 5 | 65.1 ± 5a | 74.5 ± 4.1b | 69.8 ± 5.9b | 66.1 ± 5.4a | 70.3 ± 5.9b | 68.1 ± 5.6b | 64.5 ± 6a | 66.9 ± 6.3a |
| GH | 48.5 ± 4.3 | 64.3 ± 4.7b | 62.5 ± 4.1b | 61.8 ± 4.2b | 58.3 ± 4.5b | 61.5 ± 4.2b | 60.8 ± 5b | 58.8 ± 3.9b | 57.5 ± 4.7b |
| PCS | 228.4 ± 16.3 | 265.4 ± 19.6a | 283.8 ± 16.2b | 276.8 ± 18b | 274.4 ± 16.5b | 281.3 ± 19.4b | 271.6 ± 20.3b | 259.3 ± 19.7 | 258.6 ± 22.1 |
| MCS | 221.5 ± 18.2 | 275 ± 14.7b | 264.8 ± 16.6a | 267.5 ± 16.7b | 259 ± 20a | 285 ± 16.3b | 270 ± 20.7b | 273.3 ± 19.6b | 266.2 ± 19b |
| . | Baseline . | 1 y . | 2 y . | 3 y . | 4 y . | 5 y . | 6 y . | 7 y . | 8 y . |
|---|---|---|---|---|---|---|---|---|---|
| PF | 72.3 ± 4.5 | 76.5 ± 5.4 | 81.8 ± 3.8a | 76.5 ± 5 | 76.3 ± 5.2 | 79.5 ± 4.8 | 80.3 ± 4.3 | 74.8 ± 6.2 | 73 ± 6.3 |
| RF | 52.5 ± 8.1 | 62.5 ± 8.6 | 65 ± 8.6 | 68.8 ± 7.8 | 73.8 ± 7.9a | 70 ± 8.4 | 62.5 ± 8.4 | 61.3 ± 8.6 | 61.3 ± 9.7 |
| RE | 63.3 ± 9.6 | 80 ± 6.6 | 73.3 ± 8.6 | 70 ± 9 | 71.66 ± 8.1 | 83.3 ± 6.6a | 71.7 ± 8.4 | 76.6 ± 7.7 | 71.7 ± 8.8a |
| VT | 35 ± 5 | 50.5 ± 4.8b | 49.3 ± 4.2b | 48.8 ± 4.3b | 49 ± 4.3b | 50.3 ± 5.1b | 48 ± 5.4b | 46.3 ± 5.7b | 45.3 ± 5.6a |
| MH | 60 ± 4.4 | 71.4 ± 4.1b | 70.4 ± 3.8b | 73.2 ± 3.4b | 66 ± 4.3 | 71.4 ± 3.9b | 70.4 ± 4.3b | 69.8 ± 3.92a | 71.2 ± 4b |
| SF | 63.1 ± 5.3 | 75.6 ± 4.9b | 71.9 ± 4.9 | 75.6 ± 4.7b | 72.4 ± 6.0a | 80 ± 5.6b | 75 ± 5.7a | 80.6 ± 5.6b | 78.1 ± 5.2b |
| BP | 55.1 ± 5 | 65.1 ± 5a | 74.5 ± 4.1b | 69.8 ± 5.9b | 66.1 ± 5.4a | 70.3 ± 5.9b | 68.1 ± 5.6b | 64.5 ± 6a | 66.9 ± 6.3a |
| GH | 48.5 ± 4.3 | 64.3 ± 4.7b | 62.5 ± 4.1b | 61.8 ± 4.2b | 58.3 ± 4.5b | 61.5 ± 4.2b | 60.8 ± 5b | 58.8 ± 3.9b | 57.5 ± 4.7b |
| PCS | 228.4 ± 16.3 | 265.4 ± 19.6a | 283.8 ± 16.2b | 276.8 ± 18b | 274.4 ± 16.5b | 281.3 ± 19.4b | 271.6 ± 20.3b | 259.3 ± 19.7 | 258.6 ± 22.1 |
| MCS | 221.5 ± 18.2 | 275 ± 14.7b | 264.8 ± 16.6a | 267.5 ± 16.7b | 259 ± 20a | 285 ± 16.3b | 270 ± 20.7b | 273.3 ± 19.6b | 266.2 ± 19b |
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