Numbers of Northwestern Memorial Hospitalized Patients [31] With Documented Influenza Illness (2009–2014)
| Baseline Characteristics . | Number (%) of Patients Potentially Eligible for Enrollment to an Influenza Therapeutic Trial . | Number (%) of Patients Discharged Within 48 Hours of Admission . |
|---|---|---|
| All patients | 703 (100%) | |
| ICU on admission | 7 of 703 (1%) | 0 |
| Time from symptom onset to admission ≤72 hours | 315 of 703 (45%) | 39 of 315 (12%) |
| Time from symptom onset to admission ≤96 hours | 440 of 703 (63%) | 56 of 440 (13%) |
| O2 supplementation required | 455 of 703 (65%) | 76 of 455 (17%) |
| Oxygen saturation <93% | 156 of 699 (22%) | 11 of 156 (7%) |
| O2 supplementation and O2 saturation ≤93% | 65 of 699 (9%) | 8 of 65 (12%) |
| NEWSa >2 | 493 of 698b (71%) | 53 of 493 (11%) |
| NEWS >3 | 403 of 698 (58%) | 39 of 403 (10%) |
| NEWS >4 | 294 of 698 (42%) | 23 of 294 (8%) |
| NEWS >5 | 222 of 698 (32%) | 9 of 222 (4%) |
| NEWS >6 | 156 of 698 (22%) | 2 of 161 (1%) |
| NEWS >7 | 102 of 698 (15%) | 1 of 102 (1%) |
| NEWS >8 | 62 of 698 (9%) | 0 |
| NEWS >3 or O2 supplementation requiredc | 677 of 698 (97%) | 87 of 677 (13%) |
| NEWS >3 or oxygen saturation <93%c | 415 of 698 (61%) | 40 of 415 (10%) |
| Baseline Characteristics . | Number (%) of Patients Potentially Eligible for Enrollment to an Influenza Therapeutic Trial . | Number (%) of Patients Discharged Within 48 Hours of Admission . |
|---|---|---|
| All patients | 703 (100%) | |
| ICU on admission | 7 of 703 (1%) | 0 |
| Time from symptom onset to admission ≤72 hours | 315 of 703 (45%) | 39 of 315 (12%) |
| Time from symptom onset to admission ≤96 hours | 440 of 703 (63%) | 56 of 440 (13%) |
| O2 supplementation required | 455 of 703 (65%) | 76 of 455 (17%) |
| Oxygen saturation <93% | 156 of 699 (22%) | 11 of 156 (7%) |
| O2 supplementation and O2 saturation ≤93% | 65 of 699 (9%) | 8 of 65 (12%) |
| NEWSa >2 | 493 of 698b (71%) | 53 of 493 (11%) |
| NEWS >3 | 403 of 698 (58%) | 39 of 403 (10%) |
| NEWS >4 | 294 of 698 (42%) | 23 of 294 (8%) |
| NEWS >5 | 222 of 698 (32%) | 9 of 222 (4%) |
| NEWS >6 | 156 of 698 (22%) | 2 of 161 (1%) |
| NEWS >7 | 102 of 698 (15%) | 1 of 102 (1%) |
| NEWS >8 | 62 of 698 (9%) | 0 |
| NEWS >3 or O2 supplementation requiredc | 677 of 698 (97%) | 87 of 677 (13%) |
| NEWS >3 or oxygen saturation <93%c | 415 of 698 (61%) | 40 of 415 (10%) |
Abbreviations: ICU, intensive care unit; NEWS, National Early Warning Score; NMH, Northwestern Memorial Hospital.
aSee Ref. [30].
bSix hundred ninety-eight of the 703 patients had baseline NMH information [31] for NEWS scoring.
cNote that the bottom 2 rows contain data on potential eligibility and early discharge if mixed criteria are used for enrollment.
Numbers of Northwestern Memorial Hospitalized Patients [31] With Documented Influenza Illness (2009–2014)
| Baseline Characteristics . | Number (%) of Patients Potentially Eligible for Enrollment to an Influenza Therapeutic Trial . | Number (%) of Patients Discharged Within 48 Hours of Admission . |
|---|---|---|
| All patients | 703 (100%) | |
| ICU on admission | 7 of 703 (1%) | 0 |
| Time from symptom onset to admission ≤72 hours | 315 of 703 (45%) | 39 of 315 (12%) |
| Time from symptom onset to admission ≤96 hours | 440 of 703 (63%) | 56 of 440 (13%) |
| O2 supplementation required | 455 of 703 (65%) | 76 of 455 (17%) |
| Oxygen saturation <93% | 156 of 699 (22%) | 11 of 156 (7%) |
| O2 supplementation and O2 saturation ≤93% | 65 of 699 (9%) | 8 of 65 (12%) |
| NEWSa >2 | 493 of 698b (71%) | 53 of 493 (11%) |
| NEWS >3 | 403 of 698 (58%) | 39 of 403 (10%) |
| NEWS >4 | 294 of 698 (42%) | 23 of 294 (8%) |
| NEWS >5 | 222 of 698 (32%) | 9 of 222 (4%) |
| NEWS >6 | 156 of 698 (22%) | 2 of 161 (1%) |
| NEWS >7 | 102 of 698 (15%) | 1 of 102 (1%) |
| NEWS >8 | 62 of 698 (9%) | 0 |
| NEWS >3 or O2 supplementation requiredc | 677 of 698 (97%) | 87 of 677 (13%) |
| NEWS >3 or oxygen saturation <93%c | 415 of 698 (61%) | 40 of 415 (10%) |
| Baseline Characteristics . | Number (%) of Patients Potentially Eligible for Enrollment to an Influenza Therapeutic Trial . | Number (%) of Patients Discharged Within 48 Hours of Admission . |
|---|---|---|
| All patients | 703 (100%) | |
| ICU on admission | 7 of 703 (1%) | 0 |
| Time from symptom onset to admission ≤72 hours | 315 of 703 (45%) | 39 of 315 (12%) |
| Time from symptom onset to admission ≤96 hours | 440 of 703 (63%) | 56 of 440 (13%) |
| O2 supplementation required | 455 of 703 (65%) | 76 of 455 (17%) |
| Oxygen saturation <93% | 156 of 699 (22%) | 11 of 156 (7%) |
| O2 supplementation and O2 saturation ≤93% | 65 of 699 (9%) | 8 of 65 (12%) |
| NEWSa >2 | 493 of 698b (71%) | 53 of 493 (11%) |
| NEWS >3 | 403 of 698 (58%) | 39 of 403 (10%) |
| NEWS >4 | 294 of 698 (42%) | 23 of 294 (8%) |
| NEWS >5 | 222 of 698 (32%) | 9 of 222 (4%) |
| NEWS >6 | 156 of 698 (22%) | 2 of 161 (1%) |
| NEWS >7 | 102 of 698 (15%) | 1 of 102 (1%) |
| NEWS >8 | 62 of 698 (9%) | 0 |
| NEWS >3 or O2 supplementation requiredc | 677 of 698 (97%) | 87 of 677 (13%) |
| NEWS >3 or oxygen saturation <93%c | 415 of 698 (61%) | 40 of 415 (10%) |
Abbreviations: ICU, intensive care unit; NEWS, National Early Warning Score; NMH, Northwestern Memorial Hospital.
aSee Ref. [30].
bSix hundred ninety-eight of the 703 patients had baseline NMH information [31] for NEWS scoring.
cNote that the bottom 2 rows contain data on potential eligibility and early discharge if mixed criteria are used for enrollment.
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