Multilevel Regression of Loa loa MFD Over the Period D8–D365 After Treatment
| D8-D360 . | Coef. . | 95% CI Lower Limit . | 95% CI Upper Limit . | P . |
|---|---|---|---|---|
| Time, d | –0.0003 | –0.0026 | 0.0020 | .809 |
| Quartile of pretreatment density (ref: 0–166 mf/mL) | ||||
| 167–3139 mf/mL | 3.8833 | 3.1102 | 4.6563 | .0001 |
| 3140–16 179 mf/mL | 6.7864 | 6.0258 | 7.5470 | .0001 |
| 16 180–198 660 mf/mL | 8.3234 | 7.4741 | 9.1726 | .0001 |
| Pretreatment density × time | ||||
| 167–3139 mf/mL × time | –0.0044 | –0.0074 | –0.0014 | .004 |
| 3140–16 179 mf/mL × time | –0.0020 | –0.0050 | 0.0011 | .216 |
| 16 180–198 660 mf/mL × time | –0.0019 | –0.0051 | 0.0013 | .251 |
| Sex (ref: females) | 0.0363 | –0.2337 | 0.3063 | .792 |
| Age | 0.0024 | –0.0057 | 0.0104 | .565 |
| Constant | 0.4417 | –0.2698 | 1.1533 | .224 |
| Random effect (SD) | ||||
| Study | 0 | 0 | 0.3757 | |
| Individual | 1.5937 | 1.4803 | 1.7159 | |
| Residual | 0.9353 | 0.8520 | 1.0267 |
| D8-D360 . | Coef. . | 95% CI Lower Limit . | 95% CI Upper Limit . | P . |
|---|---|---|---|---|
| Time, d | –0.0003 | –0.0026 | 0.0020 | .809 |
| Quartile of pretreatment density (ref: 0–166 mf/mL) | ||||
| 167–3139 mf/mL | 3.8833 | 3.1102 | 4.6563 | .0001 |
| 3140–16 179 mf/mL | 6.7864 | 6.0258 | 7.5470 | .0001 |
| 16 180–198 660 mf/mL | 8.3234 | 7.4741 | 9.1726 | .0001 |
| Pretreatment density × time | ||||
| 167–3139 mf/mL × time | –0.0044 | –0.0074 | –0.0014 | .004 |
| 3140–16 179 mf/mL × time | –0.0020 | –0.0050 | 0.0011 | .216 |
| 16 180–198 660 mf/mL × time | –0.0019 | –0.0051 | 0.0013 | .251 |
| Sex (ref: females) | 0.0363 | –0.2337 | 0.3063 | .792 |
| Age | 0.0024 | –0.0057 | 0.0104 | .565 |
| Constant | 0.4417 | –0.2698 | 1.1533 | .224 |
| Random effect (SD) | ||||
| Study | 0 | 0 | 0.3757 | |
| Individual | 1.5937 | 1.4803 | 1.7159 | |
| Residual | 0.9353 | 0.8520 | 1.0267 |
Abbreviations: CI, confidence interval; MFD, microfilarial density.
Multilevel Regression of Loa loa MFD Over the Period D8–D365 After Treatment
| D8-D360 . | Coef. . | 95% CI Lower Limit . | 95% CI Upper Limit . | P . |
|---|---|---|---|---|
| Time, d | –0.0003 | –0.0026 | 0.0020 | .809 |
| Quartile of pretreatment density (ref: 0–166 mf/mL) | ||||
| 167–3139 mf/mL | 3.8833 | 3.1102 | 4.6563 | .0001 |
| 3140–16 179 mf/mL | 6.7864 | 6.0258 | 7.5470 | .0001 |
| 16 180–198 660 mf/mL | 8.3234 | 7.4741 | 9.1726 | .0001 |
| Pretreatment density × time | ||||
| 167–3139 mf/mL × time | –0.0044 | –0.0074 | –0.0014 | .004 |
| 3140–16 179 mf/mL × time | –0.0020 | –0.0050 | 0.0011 | .216 |
| 16 180–198 660 mf/mL × time | –0.0019 | –0.0051 | 0.0013 | .251 |
| Sex (ref: females) | 0.0363 | –0.2337 | 0.3063 | .792 |
| Age | 0.0024 | –0.0057 | 0.0104 | .565 |
| Constant | 0.4417 | –0.2698 | 1.1533 | .224 |
| Random effect (SD) | ||||
| Study | 0 | 0 | 0.3757 | |
| Individual | 1.5937 | 1.4803 | 1.7159 | |
| Residual | 0.9353 | 0.8520 | 1.0267 |
| D8-D360 . | Coef. . | 95% CI Lower Limit . | 95% CI Upper Limit . | P . |
|---|---|---|---|---|
| Time, d | –0.0003 | –0.0026 | 0.0020 | .809 |
| Quartile of pretreatment density (ref: 0–166 mf/mL) | ||||
| 167–3139 mf/mL | 3.8833 | 3.1102 | 4.6563 | .0001 |
| 3140–16 179 mf/mL | 6.7864 | 6.0258 | 7.5470 | .0001 |
| 16 180–198 660 mf/mL | 8.3234 | 7.4741 | 9.1726 | .0001 |
| Pretreatment density × time | ||||
| 167–3139 mf/mL × time | –0.0044 | –0.0074 | –0.0014 | .004 |
| 3140–16 179 mf/mL × time | –0.0020 | –0.0050 | 0.0011 | .216 |
| 16 180–198 660 mf/mL × time | –0.0019 | –0.0051 | 0.0013 | .251 |
| Sex (ref: females) | 0.0363 | –0.2337 | 0.3063 | .792 |
| Age | 0.0024 | –0.0057 | 0.0104 | .565 |
| Constant | 0.4417 | –0.2698 | 1.1533 | .224 |
| Random effect (SD) | ||||
| Study | 0 | 0 | 0.3757 | |
| Individual | 1.5937 | 1.4803 | 1.7159 | |
| Residual | 0.9353 | 0.8520 | 1.0267 |
Abbreviations: CI, confidence interval; MFD, microfilarial density.
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