Table 3:
Open in new tab

Univariate and multivariate predictors of death within 1 year of surgery

Independents variablesUnivariate predictors
Multivariate predictors*
HR (95% CI), N = 513P-valueHR (95% CI), N = 471P-value
Age group
 65 years and below [n = 156]Reference: 1.00
 Above 65 years [n = 82]0.94 (0.45–2.00)0.878
Performance status (PS)
 PS = 0 [n = 165]Reference: 1.00
 PS greater than zero [n = 73]2.67 (1.30–5.51)0.0082.19 (1.02–4.69)0.044
Histology grade
 Low-grade tumours [n = 120]Reference: 1.00
 Poorly differentiated [n = 118]3.66 (1.63–8.17)0.0022.67 (1.14–6.21)0.023
Clinic ‘T’ stage
 Clinical Tx, Tis, T1, T2 [n = 39]Reference: 1.00
 Clinical T3 and T4 [n = 194]2.46 (0.72–8.46)0.1532.38 (0.66–8.65)0.186
Histology group
 Adeno [n = 165]Reference: 1.00
 Squamous [n = 61]1.23 (0.57–2.68)0.600
Neoadjuvant therapy
 Chemotherapy [n = 188]Reference: 1.00
 Chemoradiation [n = 50]5.30 (1.23–22.87)0.0250.27 (0.58–1.21)0.086
‘R’ status
 R0 [n = 223]Reference: 1.00
 R1/R2 [n = 15]4.29 (1.42–12.91)0.0103.09 (0.95–10.06)0.061
Clinical responseOnly evaluated in 167 patients and evaluated in a distinct multivariate analysis
 Partial/complete [n = 117]Reference: 1.00
 Minimal/stable/progression [n = 50]3.04 (1.24–7.47)0.0152.77 (1.07–7.15)0.035
Independents variablesUnivariate predictors
Multivariate predictors*
HR (95% CI), N = 513P-valueHR (95% CI), N = 471P-value
Age group
 65 years and below [n = 156]Reference: 1.00
 Above 65 years [n = 82]0.94 (0.45–2.00)0.878
Performance status (PS)
 PS = 0 [n = 165]Reference: 1.00
 PS greater than zero [n = 73]2.67 (1.30–5.51)0.0082.19 (1.02–4.69)0.044
Histology grade
 Low-grade tumours [n = 120]Reference: 1.00
 Poorly differentiated [n = 118]3.66 (1.63–8.17)0.0022.67 (1.14–6.21)0.023
Clinic ‘T’ stage
 Clinical Tx, Tis, T1, T2 [n = 39]Reference: 1.00
 Clinical T3 and T4 [n = 194]2.46 (0.72–8.46)0.1532.38 (0.66–8.65)0.186
Histology group
 Adeno [n = 165]Reference: 1.00
 Squamous [n = 61]1.23 (0.57–2.68)0.600
Neoadjuvant therapy
 Chemotherapy [n = 188]Reference: 1.00
 Chemoradiation [n = 50]5.30 (1.23–22.87)0.0250.27 (0.58–1.21)0.086
‘R’ status
 R0 [n = 223]Reference: 1.00
 R1/R2 [n = 15]4.29 (1.42–12.91)0.0103.09 (0.95–10.06)0.061
Clinical responseOnly evaluated in 167 patients and evaluated in a distinct multivariate analysis
 Partial/complete [n = 117]Reference: 1.00
 Minimal/stable/progression [n = 50]3.04 (1.24–7.47)0.0152.77 (1.07–7.15)0.035

*Only variables with a P-value of <0.20 were included in the multivariable analysis.

Table 3:
Open in new tab

Univariate and multivariate predictors of death within 1 year of surgery

Independents variablesUnivariate predictors
Multivariate predictors*
HR (95% CI), N = 513P-valueHR (95% CI), N = 471P-value
Age group
 65 years and below [n = 156]Reference: 1.00
 Above 65 years [n = 82]0.94 (0.45–2.00)0.878
Performance status (PS)
 PS = 0 [n = 165]Reference: 1.00
 PS greater than zero [n = 73]2.67 (1.30–5.51)0.0082.19 (1.02–4.69)0.044
Histology grade
 Low-grade tumours [n = 120]Reference: 1.00
 Poorly differentiated [n = 118]3.66 (1.63–8.17)0.0022.67 (1.14–6.21)0.023
Clinic ‘T’ stage
 Clinical Tx, Tis, T1, T2 [n = 39]Reference: 1.00
 Clinical T3 and T4 [n = 194]2.46 (0.72–8.46)0.1532.38 (0.66–8.65)0.186
Histology group
 Adeno [n = 165]Reference: 1.00
 Squamous [n = 61]1.23 (0.57–2.68)0.600
Neoadjuvant therapy
 Chemotherapy [n = 188]Reference: 1.00
 Chemoradiation [n = 50]5.30 (1.23–22.87)0.0250.27 (0.58–1.21)0.086
‘R’ status
 R0 [n = 223]Reference: 1.00
 R1/R2 [n = 15]4.29 (1.42–12.91)0.0103.09 (0.95–10.06)0.061
Clinical responseOnly evaluated in 167 patients and evaluated in a distinct multivariate analysis
 Partial/complete [n = 117]Reference: 1.00
 Minimal/stable/progression [n = 50]3.04 (1.24–7.47)0.0152.77 (1.07–7.15)0.035
Independents variablesUnivariate predictors
Multivariate predictors*
HR (95% CI), N = 513P-valueHR (95% CI), N = 471P-value
Age group
 65 years and below [n = 156]Reference: 1.00
 Above 65 years [n = 82]0.94 (0.45–2.00)0.878
Performance status (PS)
 PS = 0 [n = 165]Reference: 1.00
 PS greater than zero [n = 73]2.67 (1.30–5.51)0.0082.19 (1.02–4.69)0.044
Histology grade
 Low-grade tumours [n = 120]Reference: 1.00
 Poorly differentiated [n = 118]3.66 (1.63–8.17)0.0022.67 (1.14–6.21)0.023
Clinic ‘T’ stage
 Clinical Tx, Tis, T1, T2 [n = 39]Reference: 1.00
 Clinical T3 and T4 [n = 194]2.46 (0.72–8.46)0.1532.38 (0.66–8.65)0.186
Histology group
 Adeno [n = 165]Reference: 1.00
 Squamous [n = 61]1.23 (0.57–2.68)0.600
Neoadjuvant therapy
 Chemotherapy [n = 188]Reference: 1.00
 Chemoradiation [n = 50]5.30 (1.23–22.87)0.0250.27 (0.58–1.21)0.086
‘R’ status
 R0 [n = 223]Reference: 1.00
 R1/R2 [n = 15]4.29 (1.42–12.91)0.0103.09 (0.95–10.06)0.061
Clinical responseOnly evaluated in 167 patients and evaluated in a distinct multivariate analysis
 Partial/complete [n = 117]Reference: 1.00
 Minimal/stable/progression [n = 50]3.04 (1.24–7.47)0.0152.77 (1.07–7.15)0.035

*Only variables with a P-value of <0.20 were included in the multivariable analysis.

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