Neuroradiological Features of 71 Patients With Neurolisteriosis and Neuroimaging
| Neuroradiological Finding . | Lesions . | . | ||
|---|---|---|---|---|
| No. of Patients With Radiological Lesionsa, N = 71 . | No. of Patients With Lesions on MRIa, N = 46 . | No. of Patients With Lesions on CTa, N = 30 . | P Value CT vs MRI . | |
| Meninges | ||||
| Lepto and/or pachy-meningeal enhancement | 25/71 (35) | 20/46 (43) | 6/30 (20) | .048 |
| Parenchyma | ||||
| Brain abscessb | 4/71 (6) | 3/46 (7) | 1/30 (3) | NS |
| Nodule evocative of abscessb | 7//71 (10) | 7/46 (15) | 1/30 (3) | NS |
| Nonspecific white matter lesion | 42/71 (59) | 30/46 (65) | 14/30 (47) | NS |
| Atrophyc | 34/71 (48) | 24/46 (52) | 12/30 (40) | NS |
| Dilated Virchow-Robin spaces | 22/71 (31) | 20/46 (43) | 6/30 (20) | .048 |
| Cerebral herniationd | 2/71 (2) | 2/46 (4) | 1/30 (3) | NS |
| Diffuse cerebral edema | 1/71 (1) | 1/46 (2) | - | NS |
| Ventricles | ||||
| Contrast-enhancing ventricles | 2/71 (3) | 2/46 (4) | 1/30 (3) | NS |
| Hydrocephalus | 6/71 (9) | 1/46 (2) | 6/30 (20) | .01 |
| Brain vessels | ||||
| Radiological vasculitise | 3/71 (5) | 3/46 (7) | 1/30 (3) | NS |
| Hemorrhage | 11/71 (15) | 10/46 (22) | 1/30 (3) | .04 |
| Ischemiaf | 8/71 (11) | 8/46 (17) | 1/30 (3) | NS |
| Concomitant tumor imageg | 5/71 (7) | 4/46 (8) | 2/30 (6) | NS |
| Normal | 9/71 (13) | 2/46 (4) | 7/30 (23) | .02 |
| Neuroradiological Finding . | Lesions . | . | ||
|---|---|---|---|---|
| No. of Patients With Radiological Lesionsa, N = 71 . | No. of Patients With Lesions on MRIa, N = 46 . | No. of Patients With Lesions on CTa, N = 30 . | P Value CT vs MRI . | |
| Meninges | ||||
| Lepto and/or pachy-meningeal enhancement | 25/71 (35) | 20/46 (43) | 6/30 (20) | .048 |
| Parenchyma | ||||
| Brain abscessb | 4/71 (6) | 3/46 (7) | 1/30 (3) | NS |
| Nodule evocative of abscessb | 7//71 (10) | 7/46 (15) | 1/30 (3) | NS |
| Nonspecific white matter lesion | 42/71 (59) | 30/46 (65) | 14/30 (47) | NS |
| Atrophyc | 34/71 (48) | 24/46 (52) | 12/30 (40) | NS |
| Dilated Virchow-Robin spaces | 22/71 (31) | 20/46 (43) | 6/30 (20) | .048 |
| Cerebral herniationd | 2/71 (2) | 2/46 (4) | 1/30 (3) | NS |
| Diffuse cerebral edema | 1/71 (1) | 1/46 (2) | - | NS |
| Ventricles | ||||
| Contrast-enhancing ventricles | 2/71 (3) | 2/46 (4) | 1/30 (3) | NS |
| Hydrocephalus | 6/71 (9) | 1/46 (2) | 6/30 (20) | .01 |
| Brain vessels | ||||
| Radiological vasculitise | 3/71 (5) | 3/46 (7) | 1/30 (3) | NS |
| Hemorrhage | 11/71 (15) | 10/46 (22) | 1/30 (3) | .04 |
| Ischemiaf | 8/71 (11) | 8/46 (17) | 1/30 (3) | NS |
| Concomitant tumor imageg | 5/71 (7) | 4/46 (8) | 2/30 (6) | NS |
| Normal | 9/71 (13) | 2/46 (4) | 7/30 (23) | .02 |
Abbreviations: CT, computed tomography; MRI, magnetic resonance imaging; NS, not significant.
aData presented are those from exams 1 and 2. When 1 patient had benefited from 2 exams with the same procedure (computed tomography or magnetic resonance), data from the first exam were retained for analysis. Patients could have images evidenced in both procedures; therefore, total numbers are not the sum of MRI plus CT scan numbers.
bBrain abscesses and nodules were localized in the frontal lobe, temporal lobe (n = 1, each), thalami (n = 2), cerebellum (n = 1), brainstem (n = 4), or brainstem and occipital lobe (n = 1).
cAtrophy was classified as diffuse in 27/33 (82%; cortical in 6, subcortical in 7, and both cortical and subcortical in 14) and as focal in 6/33 (18%).
dCerebral herniation was classified as uncal or subfalcine (n = 1 each).
eRadiological vasculitis was defined as enhanced cortical grey matter after injection of gadolinium chelates on T1-weighted images on MRI or after infection of iodine contrast media on helicoidal CT scan, possibly associated with hemorrhages or ischemic lesions.
fIschemic images were considered as sequellar lesions in 3/8 cases, and recent in 5/8. In the 5 images reflecting recent lesions, they could be related to the radiological vasculitis in 2/5 cases; altogether, they were subtentorial in 3/5 and supratentorial in 2/5 cases.
gTumor images included meningioma (n = 2) and histologically confirmed malignant brain tumor (n = 3).
Neuroradiological Features of 71 Patients With Neurolisteriosis and Neuroimaging
| Neuroradiological Finding . | Lesions . | . | ||
|---|---|---|---|---|
| No. of Patients With Radiological Lesionsa, N = 71 . | No. of Patients With Lesions on MRIa, N = 46 . | No. of Patients With Lesions on CTa, N = 30 . | P Value CT vs MRI . | |
| Meninges | ||||
| Lepto and/or pachy-meningeal enhancement | 25/71 (35) | 20/46 (43) | 6/30 (20) | .048 |
| Parenchyma | ||||
| Brain abscessb | 4/71 (6) | 3/46 (7) | 1/30 (3) | NS |
| Nodule evocative of abscessb | 7//71 (10) | 7/46 (15) | 1/30 (3) | NS |
| Nonspecific white matter lesion | 42/71 (59) | 30/46 (65) | 14/30 (47) | NS |
| Atrophyc | 34/71 (48) | 24/46 (52) | 12/30 (40) | NS |
| Dilated Virchow-Robin spaces | 22/71 (31) | 20/46 (43) | 6/30 (20) | .048 |
| Cerebral herniationd | 2/71 (2) | 2/46 (4) | 1/30 (3) | NS |
| Diffuse cerebral edema | 1/71 (1) | 1/46 (2) | - | NS |
| Ventricles | ||||
| Contrast-enhancing ventricles | 2/71 (3) | 2/46 (4) | 1/30 (3) | NS |
| Hydrocephalus | 6/71 (9) | 1/46 (2) | 6/30 (20) | .01 |
| Brain vessels | ||||
| Radiological vasculitise | 3/71 (5) | 3/46 (7) | 1/30 (3) | NS |
| Hemorrhage | 11/71 (15) | 10/46 (22) | 1/30 (3) | .04 |
| Ischemiaf | 8/71 (11) | 8/46 (17) | 1/30 (3) | NS |
| Concomitant tumor imageg | 5/71 (7) | 4/46 (8) | 2/30 (6) | NS |
| Normal | 9/71 (13) | 2/46 (4) | 7/30 (23) | .02 |
| Neuroradiological Finding . | Lesions . | . | ||
|---|---|---|---|---|
| No. of Patients With Radiological Lesionsa, N = 71 . | No. of Patients With Lesions on MRIa, N = 46 . | No. of Patients With Lesions on CTa, N = 30 . | P Value CT vs MRI . | |
| Meninges | ||||
| Lepto and/or pachy-meningeal enhancement | 25/71 (35) | 20/46 (43) | 6/30 (20) | .048 |
| Parenchyma | ||||
| Brain abscessb | 4/71 (6) | 3/46 (7) | 1/30 (3) | NS |
| Nodule evocative of abscessb | 7//71 (10) | 7/46 (15) | 1/30 (3) | NS |
| Nonspecific white matter lesion | 42/71 (59) | 30/46 (65) | 14/30 (47) | NS |
| Atrophyc | 34/71 (48) | 24/46 (52) | 12/30 (40) | NS |
| Dilated Virchow-Robin spaces | 22/71 (31) | 20/46 (43) | 6/30 (20) | .048 |
| Cerebral herniationd | 2/71 (2) | 2/46 (4) | 1/30 (3) | NS |
| Diffuse cerebral edema | 1/71 (1) | 1/46 (2) | - | NS |
| Ventricles | ||||
| Contrast-enhancing ventricles | 2/71 (3) | 2/46 (4) | 1/30 (3) | NS |
| Hydrocephalus | 6/71 (9) | 1/46 (2) | 6/30 (20) | .01 |
| Brain vessels | ||||
| Radiological vasculitise | 3/71 (5) | 3/46 (7) | 1/30 (3) | NS |
| Hemorrhage | 11/71 (15) | 10/46 (22) | 1/30 (3) | .04 |
| Ischemiaf | 8/71 (11) | 8/46 (17) | 1/30 (3) | NS |
| Concomitant tumor imageg | 5/71 (7) | 4/46 (8) | 2/30 (6) | NS |
| Normal | 9/71 (13) | 2/46 (4) | 7/30 (23) | .02 |
Abbreviations: CT, computed tomography; MRI, magnetic resonance imaging; NS, not significant.
aData presented are those from exams 1 and 2. When 1 patient had benefited from 2 exams with the same procedure (computed tomography or magnetic resonance), data from the first exam were retained for analysis. Patients could have images evidenced in both procedures; therefore, total numbers are not the sum of MRI plus CT scan numbers.
bBrain abscesses and nodules were localized in the frontal lobe, temporal lobe (n = 1, each), thalami (n = 2), cerebellum (n = 1), brainstem (n = 4), or brainstem and occipital lobe (n = 1).
cAtrophy was classified as diffuse in 27/33 (82%; cortical in 6, subcortical in 7, and both cortical and subcortical in 14) and as focal in 6/33 (18%).
dCerebral herniation was classified as uncal or subfalcine (n = 1 each).
eRadiological vasculitis was defined as enhanced cortical grey matter after injection of gadolinium chelates on T1-weighted images on MRI or after infection of iodine contrast media on helicoidal CT scan, possibly associated with hemorrhages or ischemic lesions.
fIschemic images were considered as sequellar lesions in 3/8 cases, and recent in 5/8. In the 5 images reflecting recent lesions, they could be related to the radiological vasculitis in 2/5 cases; altogether, they were subtentorial in 3/5 and supratentorial in 2/5 cases.
gTumor images included meningioma (n = 2) and histologically confirmed malignant brain tumor (n = 3).
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