Associations of SB and Moderate to Vigorous Physical Activity With Cardiometabolic Risk Factors Among US Hispanic/Latino Youth: Results From Multivariable Linear Regression (n = 1426)
| Dependent Variable . | No. . | Model 1 . | Model 2 a . | Model 3 b . | |||
|---|---|---|---|---|---|---|---|
| SB . | MVPA . | SB . | MVPA . | SB . | MVPA . | ||
| LDL-C, mg/dL | 1396 | 0.12 (0.42) | −0.55 (0.55) | −0.64 (0.60) | −0.91 (0.86) | −0.78 (0.59) | −0.45 (0.86) |
| HDL-C, mg/dL | 1398 | −0.96 (0.22)c | 1.11 (0.33)d | −0.72 (0.29)e | 0.37 (0.42) | −0.63 (0.26)e | −0.18 (0.38) |
| Triglycerides, mg/dLf | 1398 | 0.03 (0.01)d | −0.06 (0.01)c | −0.02 (0.01) | −0.06 (0.02)d | −0.02 (0.01) | −0.04 (0.02)e |
| SBP, percentile | 1423 | −0.16 (0.46) | −0.09 (0.67) | −0.73 (0.66) | −0.52 (1.02) | −0.53 (0.68) | −0.30 (1.00) |
| DBP, percentile | 1424 | 0.36 (0.42) | −0.90 (0.59) | −0.54 (0.56) | −1.14 (0.85) | −0.53 (0.57) | −0.67 (0.84) |
| Fasting glucose, mg/dL | 1373 | 0.15 (0.11) | −0.10 (0.17) | 0.17 (0.17) | 0.09 (0.26) | 0.16 (0.17) | 0.17 (0.26) |
| Fasting insulin, mU/Lf | 1367 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HOMA-IRf | 1365 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HbA1c, % | 1372 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) |
| hs-CRP, mg/Lf | 1423 | 0.06 (0.03)e | −0.10 (0.04)e | 0.02 (0.03) | −0.08 (0.05) | 0.00 (0.03) | 0.00 (0.04) |
| Adiponectin, ng/mL | 1371 | −0.13 (0.08) | 0.22 (0.11)e | −0.05 (0.11) | 0.21 (0.17) | −0.02 (0.11) | 0.01 (0.16) |
| PAI-1, ng/mLf | 1369 | 0.07 (0.02)c | −0.10 (0.02)d | 0.02 (0.02) | −0.07 (0.03)e | 0.01 (0.02) | −0.01 (0.03) |
| E-selectin, ng/mLf | 1396 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.03 (0.02) | −0.01 (0.01) | −0.02 (0.02) |
| sRAGE, pg/mLf | 689 | −0.02 (0.01) | 0.01 (0.01) | −0.03 (0.01) | −0.01 (0.02) | −0.02 (0.01) | −0.02 (0.02) |
| Dependent Variable . | No. . | Model 1 . | Model 2 a . | Model 3 b . | |||
|---|---|---|---|---|---|---|---|
| SB . | MVPA . | SB . | MVPA . | SB . | MVPA . | ||
| LDL-C, mg/dL | 1396 | 0.12 (0.42) | −0.55 (0.55) | −0.64 (0.60) | −0.91 (0.86) | −0.78 (0.59) | −0.45 (0.86) |
| HDL-C, mg/dL | 1398 | −0.96 (0.22)c | 1.11 (0.33)d | −0.72 (0.29)e | 0.37 (0.42) | −0.63 (0.26)e | −0.18 (0.38) |
| Triglycerides, mg/dLf | 1398 | 0.03 (0.01)d | −0.06 (0.01)c | −0.02 (0.01) | −0.06 (0.02)d | −0.02 (0.01) | −0.04 (0.02)e |
| SBP, percentile | 1423 | −0.16 (0.46) | −0.09 (0.67) | −0.73 (0.66) | −0.52 (1.02) | −0.53 (0.68) | −0.30 (1.00) |
| DBP, percentile | 1424 | 0.36 (0.42) | −0.90 (0.59) | −0.54 (0.56) | −1.14 (0.85) | −0.53 (0.57) | −0.67 (0.84) |
| Fasting glucose, mg/dL | 1373 | 0.15 (0.11) | −0.10 (0.17) | 0.17 (0.17) | 0.09 (0.26) | 0.16 (0.17) | 0.17 (0.26) |
| Fasting insulin, mU/Lf | 1367 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HOMA-IRf | 1365 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HbA1c, % | 1372 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) |
| hs-CRP, mg/Lf | 1423 | 0.06 (0.03)e | −0.10 (0.04)e | 0.02 (0.03) | −0.08 (0.05) | 0.00 (0.03) | 0.00 (0.04) |
| Adiponectin, ng/mL | 1371 | −0.13 (0.08) | 0.22 (0.11)e | −0.05 (0.11) | 0.21 (0.17) | −0.02 (0.11) | 0.01 (0.16) |
| PAI-1, ng/mLf | 1369 | 0.07 (0.02)c | −0.10 (0.02)d | 0.02 (0.02) | −0.07 (0.03)e | 0.01 (0.02) | −0.01 (0.03) |
| E-selectin, ng/mLf | 1396 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.03 (0.02) | −0.01 (0.01) | −0.02 (0.02) |
| sRAGE, pg/mLf | 689 | −0.02 (0.01) | 0.01 (0.01) | −0.03 (0.01) | −0.01 (0.02) | −0.02 (0.01) | −0.02 (0.02) |
Data are given as β values (SE), unless otherwise indicated, associated with a 30-min/d increase in SB or 15-min/d increase in MVPA; all models were adjusted for age, sex, Hispanic background, field center, immigrant generation, parental education level, annual family income, and diet quality; models of MPVA were additionally adjusted for accelerometer wear time.
Abbreviations: CVD, cardiovascular disease; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure.
Model 2 contains SB and MVPA simultaneously.
Model 3 contains SB and MVPA simultaneously, while additionally adjusting for waist circumference and BMI percentile as mediators.
P < 0.0001.
P < 0.01.
P < 0.05.
Triglycerides, fasting insulin, HOMA-IR, hs-CRP, PAI-1, E-selectin, and sRAGE were modeled as log-transformed; therefore, β values approximately represent percentage changes.
Associations of SB and Moderate to Vigorous Physical Activity With Cardiometabolic Risk Factors Among US Hispanic/Latino Youth: Results From Multivariable Linear Regression (n = 1426)
| Dependent Variable . | No. . | Model 1 . | Model 2 a . | Model 3 b . | |||
|---|---|---|---|---|---|---|---|
| SB . | MVPA . | SB . | MVPA . | SB . | MVPA . | ||
| LDL-C, mg/dL | 1396 | 0.12 (0.42) | −0.55 (0.55) | −0.64 (0.60) | −0.91 (0.86) | −0.78 (0.59) | −0.45 (0.86) |
| HDL-C, mg/dL | 1398 | −0.96 (0.22)c | 1.11 (0.33)d | −0.72 (0.29)e | 0.37 (0.42) | −0.63 (0.26)e | −0.18 (0.38) |
| Triglycerides, mg/dLf | 1398 | 0.03 (0.01)d | −0.06 (0.01)c | −0.02 (0.01) | −0.06 (0.02)d | −0.02 (0.01) | −0.04 (0.02)e |
| SBP, percentile | 1423 | −0.16 (0.46) | −0.09 (0.67) | −0.73 (0.66) | −0.52 (1.02) | −0.53 (0.68) | −0.30 (1.00) |
| DBP, percentile | 1424 | 0.36 (0.42) | −0.90 (0.59) | −0.54 (0.56) | −1.14 (0.85) | −0.53 (0.57) | −0.67 (0.84) |
| Fasting glucose, mg/dL | 1373 | 0.15 (0.11) | −0.10 (0.17) | 0.17 (0.17) | 0.09 (0.26) | 0.16 (0.17) | 0.17 (0.26) |
| Fasting insulin, mU/Lf | 1367 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HOMA-IRf | 1365 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HbA1c, % | 1372 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) |
| hs-CRP, mg/Lf | 1423 | 0.06 (0.03)e | −0.10 (0.04)e | 0.02 (0.03) | −0.08 (0.05) | 0.00 (0.03) | 0.00 (0.04) |
| Adiponectin, ng/mL | 1371 | −0.13 (0.08) | 0.22 (0.11)e | −0.05 (0.11) | 0.21 (0.17) | −0.02 (0.11) | 0.01 (0.16) |
| PAI-1, ng/mLf | 1369 | 0.07 (0.02)c | −0.10 (0.02)d | 0.02 (0.02) | −0.07 (0.03)e | 0.01 (0.02) | −0.01 (0.03) |
| E-selectin, ng/mLf | 1396 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.03 (0.02) | −0.01 (0.01) | −0.02 (0.02) |
| sRAGE, pg/mLf | 689 | −0.02 (0.01) | 0.01 (0.01) | −0.03 (0.01) | −0.01 (0.02) | −0.02 (0.01) | −0.02 (0.02) |
| Dependent Variable . | No. . | Model 1 . | Model 2 a . | Model 3 b . | |||
|---|---|---|---|---|---|---|---|
| SB . | MVPA . | SB . | MVPA . | SB . | MVPA . | ||
| LDL-C, mg/dL | 1396 | 0.12 (0.42) | −0.55 (0.55) | −0.64 (0.60) | −0.91 (0.86) | −0.78 (0.59) | −0.45 (0.86) |
| HDL-C, mg/dL | 1398 | −0.96 (0.22)c | 1.11 (0.33)d | −0.72 (0.29)e | 0.37 (0.42) | −0.63 (0.26)e | −0.18 (0.38) |
| Triglycerides, mg/dLf | 1398 | 0.03 (0.01)d | −0.06 (0.01)c | −0.02 (0.01) | −0.06 (0.02)d | −0.02 (0.01) | −0.04 (0.02)e |
| SBP, percentile | 1423 | −0.16 (0.46) | −0.09 (0.67) | −0.73 (0.66) | −0.52 (1.02) | −0.53 (0.68) | −0.30 (1.00) |
| DBP, percentile | 1424 | 0.36 (0.42) | −0.90 (0.59) | −0.54 (0.56) | −1.14 (0.85) | −0.53 (0.57) | −0.67 (0.84) |
| Fasting glucose, mg/dL | 1373 | 0.15 (0.11) | −0.10 (0.17) | 0.17 (0.17) | 0.09 (0.26) | 0.16 (0.17) | 0.17 (0.26) |
| Fasting insulin, mU/Lf | 1367 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HOMA-IRf | 1365 | 0.07 (0.01)c | −0.11 (0.02)c | 0.02 (0.02) | −0.08 (0.03)d | 0.01 (0.01) | −0.03 (0.02) |
| HbA1c, % | 1372 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.01 (0.01) |
| hs-CRP, mg/Lf | 1423 | 0.06 (0.03)e | −0.10 (0.04)e | 0.02 (0.03) | −0.08 (0.05) | 0.00 (0.03) | 0.00 (0.04) |
| Adiponectin, ng/mL | 1371 | −0.13 (0.08) | 0.22 (0.11)e | −0.05 (0.11) | 0.21 (0.17) | −0.02 (0.11) | 0.01 (0.16) |
| PAI-1, ng/mLf | 1369 | 0.07 (0.02)c | −0.10 (0.02)d | 0.02 (0.02) | −0.07 (0.03)e | 0.01 (0.02) | −0.01 (0.03) |
| E-selectin, ng/mLf | 1396 | 0.00 (0.01) | −0.01 (0.01) | −0.01 (0.01) | −0.03 (0.02) | −0.01 (0.01) | −0.02 (0.02) |
| sRAGE, pg/mLf | 689 | −0.02 (0.01) | 0.01 (0.01) | −0.03 (0.01) | −0.01 (0.02) | −0.02 (0.01) | −0.02 (0.02) |
Data are given as β values (SE), unless otherwise indicated, associated with a 30-min/d increase in SB or 15-min/d increase in MVPA; all models were adjusted for age, sex, Hispanic background, field center, immigrant generation, parental education level, annual family income, and diet quality; models of MPVA were additionally adjusted for accelerometer wear time.
Abbreviations: CVD, cardiovascular disease; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure.
Model 2 contains SB and MVPA simultaneously.
Model 3 contains SB and MVPA simultaneously, while additionally adjusting for waist circumference and BMI percentile as mediators.
P < 0.0001.
P < 0.01.
P < 0.05.
Triglycerides, fasting insulin, HOMA-IR, hs-CRP, PAI-1, E-selectin, and sRAGE were modeled as log-transformed; therefore, β values approximately represent percentage changes.
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