Table 3.

Correlation between Plasma sTNFR2 Levels and Cognitive Function

TotalSchizophreniaHealthy Control
nrPCorrected P valuenrPCorrected P valuenrPCorrected P value
IQWAISVIQ263-0.192.4×10–3**.031*870.14n.s.n.s.176-0.19.012*n.s.
PIQ263-0.218.1×10–4***.011*870.04n.s.n.s.176-0.13n.s.n.s.
FIQ263-0.223.5×10–4***4.5×10–3***870.09n.s.n.s.176-0.19.012*n.s.
VC263-0.16.011*n.s.870.16n.s.n.s.176-0.19.014*n.s.
PO263-0.21.5×10–3***.019*870.03n.s.n.s.176-0.16.036*n.s.
WM260-0.169.5×10–3**n.s.840.08n.s.n.s.176-0.15.049*n.s.
PS260-0.21.0×10–3***.013*840.01n.s.n.s.176-0.1n.s.n.s.
MemoryWMSVerM267-0.261.3×10–5***1.7×10–4***91-0.02n.s.n.s.176-0.15.049*n.s.
ViM267-0.222.2×10–4***2.8×10–3***91-0.13n.s.n.s.176-0.13n.s.n.s.
GM267-0.282.2×10–6***2.9×10–5***91-0.06n.s.n.s.176-0.16.03*n.s.
A/C267-0.15.018*n.s.910.02n.s.n.s.176-0.06n.s.n.s.
DR267-0.262.2×10–5***2.9×10–4***91-0.11n.s.n.s.176-0.11n.s.n.s.
AVLTtotal recall257-0.362.4×10–9***3.2×10–8***81-0.23.03*n.s.176-0.321.2×10–5***1.6×10–4***
TotalSchizophreniaHealthy Control
nrPCorrected P valuenrPCorrected P valuenrPCorrected P value
IQWAISVIQ263-0.192.4×10–3**.031*870.14n.s.n.s.176-0.19.012*n.s.
PIQ263-0.218.1×10–4***.011*870.04n.s.n.s.176-0.13n.s.n.s.
FIQ263-0.223.5×10–4***4.5×10–3***870.09n.s.n.s.176-0.19.012*n.s.
VC263-0.16.011*n.s.870.16n.s.n.s.176-0.19.014*n.s.
PO263-0.21.5×10–3***.019*870.03n.s.n.s.176-0.16.036*n.s.
WM260-0.169.5×10–3**n.s.840.08n.s.n.s.176-0.15.049*n.s.
PS260-0.21.0×10–3***.013*840.01n.s.n.s.176-0.1n.s.n.s.
MemoryWMSVerM267-0.261.3×10–5***1.7×10–4***91-0.02n.s.n.s.176-0.15.049*n.s.
ViM267-0.222.2×10–4***2.8×10–3***91-0.13n.s.n.s.176-0.13n.s.n.s.
GM267-0.282.2×10–6***2.9×10–5***91-0.06n.s.n.s.176-0.16.03*n.s.
A/C267-0.15.018*n.s.910.02n.s.n.s.176-0.06n.s.n.s.
DR267-0.262.2×10–5***2.9×10–4***91-0.11n.s.n.s.176-0.11n.s.n.s.
AVLTtotal recall257-0.362.4×10–9***3.2×10–8***81-0.23.03*n.s.176-0.321.2×10–5***1.6×10–4***

*P<.05, **P<.01, ***P<.005

Abbreviations: A/C, Attention and Concentration; DR, delayed recall; FIQ, Full-scale IQ; GM, General Memory; n.s., not significant; VIQ, Verbal IQ; PIQ, Performance IQ; PO, Picture Completion Block Design and Matrix Reasoning; PS, Block Design and Matrix Reasoning; VerM, Verbal Memory; ViM, Visual Memory; WM, Airthmetic, Digit Span and Letter Number Sequencing.

Table 3.

Correlation between Plasma sTNFR2 Levels and Cognitive Function

TotalSchizophreniaHealthy Control
nrPCorrected P valuenrPCorrected P valuenrPCorrected P value
IQWAISVIQ263-0.192.4×10–3**.031*870.14n.s.n.s.176-0.19.012*n.s.
PIQ263-0.218.1×10–4***.011*870.04n.s.n.s.176-0.13n.s.n.s.
FIQ263-0.223.5×10–4***4.5×10–3***870.09n.s.n.s.176-0.19.012*n.s.
VC263-0.16.011*n.s.870.16n.s.n.s.176-0.19.014*n.s.
PO263-0.21.5×10–3***.019*870.03n.s.n.s.176-0.16.036*n.s.
WM260-0.169.5×10–3**n.s.840.08n.s.n.s.176-0.15.049*n.s.
PS260-0.21.0×10–3***.013*840.01n.s.n.s.176-0.1n.s.n.s.
MemoryWMSVerM267-0.261.3×10–5***1.7×10–4***91-0.02n.s.n.s.176-0.15.049*n.s.
ViM267-0.222.2×10–4***2.8×10–3***91-0.13n.s.n.s.176-0.13n.s.n.s.
GM267-0.282.2×10–6***2.9×10–5***91-0.06n.s.n.s.176-0.16.03*n.s.
A/C267-0.15.018*n.s.910.02n.s.n.s.176-0.06n.s.n.s.
DR267-0.262.2×10–5***2.9×10–4***91-0.11n.s.n.s.176-0.11n.s.n.s.
AVLTtotal recall257-0.362.4×10–9***3.2×10–8***81-0.23.03*n.s.176-0.321.2×10–5***1.6×10–4***
TotalSchizophreniaHealthy Control
nrPCorrected P valuenrPCorrected P valuenrPCorrected P value
IQWAISVIQ263-0.192.4×10–3**.031*870.14n.s.n.s.176-0.19.012*n.s.
PIQ263-0.218.1×10–4***.011*870.04n.s.n.s.176-0.13n.s.n.s.
FIQ263-0.223.5×10–4***4.5×10–3***870.09n.s.n.s.176-0.19.012*n.s.
VC263-0.16.011*n.s.870.16n.s.n.s.176-0.19.014*n.s.
PO263-0.21.5×10–3***.019*870.03n.s.n.s.176-0.16.036*n.s.
WM260-0.169.5×10–3**n.s.840.08n.s.n.s.176-0.15.049*n.s.
PS260-0.21.0×10–3***.013*840.01n.s.n.s.176-0.1n.s.n.s.
MemoryWMSVerM267-0.261.3×10–5***1.7×10–4***91-0.02n.s.n.s.176-0.15.049*n.s.
ViM267-0.222.2×10–4***2.8×10–3***91-0.13n.s.n.s.176-0.13n.s.n.s.
GM267-0.282.2×10–6***2.9×10–5***91-0.06n.s.n.s.176-0.16.03*n.s.
A/C267-0.15.018*n.s.910.02n.s.n.s.176-0.06n.s.n.s.
DR267-0.262.2×10–5***2.9×10–4***91-0.11n.s.n.s.176-0.11n.s.n.s.
AVLTtotal recall257-0.362.4×10–9***3.2×10–8***81-0.23.03*n.s.176-0.321.2×10–5***1.6×10–4***

*P<.05, **P<.01, ***P<.005

Abbreviations: A/C, Attention and Concentration; DR, delayed recall; FIQ, Full-scale IQ; GM, General Memory; n.s., not significant; VIQ, Verbal IQ; PIQ, Performance IQ; PO, Picture Completion Block Design and Matrix Reasoning; PS, Block Design and Matrix Reasoning; VerM, Verbal Memory; ViM, Visual Memory; WM, Airthmetic, Digit Span and Letter Number Sequencing.

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