Table 1. Multilocus Sequence Typing...

Sample ID	Originating State	Specimen Type	clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
Borrelia burgdorferi
15–2664	MN	Blood	18	12	1	11	2	15	1	2	29
15–3449	MN	Blood	4	12	1	11	2	15	1	2	756^a
15–4099	MN	Blood	8	1	1	1	4	16	1	7	32
15–6241	MN	Blood	14	1	5	2	2	1	1	10	530
15–6673	MN	Blood	14	1	5	2	2	1	1	10	530
15–6967	MN	Blood	14	1	5	2	2	1	1	10	530
15–8161	MN	Blood	14	1	5	2	2	1	1	10	530
15–3553	PA	Blood	5	5	4	5	5	5	1	6	8
15–0285	WI	Blood	8	1	1	1	4	16	1	7	32
15–3913	WI	Blood	128	12	1	8	1	6	1	10	758^a
15–4064	WI	Blood	14	1	5	2	2	1	1	10	530
15–1932	IA	CSF	8	1	1	14	2	6	1	10	48
15–0078	MD	Synovial fluid	4	1	1	1	224^a	6	1	217^a	754^a
15–1218	MN	Synovial fluid	24	14	4	18	11	19	1	12	56
16–1191	MN	Synovial fluid	8	1	1	14	2	6	1	10	48
15–2880	MO	Synovial fluid	4	4	3	3	3	3	3	3	19
15–5375	NY	Synovial fluid	4	1	1	1	225^a	6	1	7	759^a
15–7208	NY	Synovial fluid	6	1	5	1	1	7	1	8	7
15–8685	NY	Synovial fluid	1	1	1	1	1	1	1	1	1
15–4205	PA	Synovial fluid	14	1	1	2	1	6	200^a	7	758^a
15–8607	PA	Synovial fluid	5	5	188^a	5	5	5	1	6	760^a
15–1840	VA	Synovial fluid	4	4	3	217^a	3	3	3	3	755^a
15–1893	VA	Synovial fluid	4	1	1	1	1	6	1	7	3
15–8808	VA	Synovial fluid	4	1	189^a	1	1	6	1	7	761^a
Borrelia mayonii
15–0238	MN	Blood	218	182	166	191	201	209	174	193	674
15–0290	MN	Blood	218	182	166	191	202	209	174	193	675
15–1071	MN	Blood	218	182	166	191	201	209	174	193	674
15–3469	WI	Blood	218	182	166	191	201	209	174	193	674
15–4246	MN	Blood	218	182	166	191	201	209	174	193	674
15–5283	MN	Blood	218	182	166	191	201	209	174	193	674
15–5922	MN	Blood	218	182	166	218^a	201	209	174	193	762^a
15–8522	MN	Blood	218	182	166	191	201	209	174	193	674
15–8523	MN	Blood	218	182	166	191	201	209	174	193	674
Borrelia miyamotoi
15–0196	WI	Blood	200	117	151	173	184	191	160	70	634
15–0228	MN	Blood	200	117	151	173	184	191	160	70	634
15–4374	NJ	Blood	200	117	151	173	184	191	160	70	634
15–6004	MN	Blood	200	117	151	173	184	191	160	70	634
15–6731	NJ	Blood	200	117	151	173	184	191	160	70	634
15–7268	NJ	Blood	200	117	151	173	184	191	160	70	634
15–8793	MN	Blood	200	117	151	173	184	191	160	70	634
16–0683	NJ	Blood	200	117	151	173	184	191	160	70	634
B. hermsii
15–5636	MT	Blood	246^a	206^a	190^a	219^a	226^a	236^a	201^a	218^a	763^a
Candidatus Borrelia johnsonii
			clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
15–3581	WI	Blood	247^a	207^a	191^a	220^a	227^a	237^a	202^a	219^a	764^a

Sample ID

Originating State

Specimen Type

clpA

clpX

nifS

pepX

pyrG

recG

rplB

uvrA

Borrelia burgdorferi

15–2664

Blood

15–3449

Blood

756^a

15–4099

Blood

15–6241

Blood

530

15–6673

Blood

530

15–6967

Blood

530

15–8161

Blood

530

15–3553

Blood

15–0285

Blood

15–3913

Blood

128

758^a

15–4064

Blood

530

15–1932

CSF

15–0078

Synovial fluid

224^a

217^a

754^a

15–1218

Synovial fluid

16–1191

Synovial fluid

15–2880

Synovial fluid

15–5375

Synovial fluid

225^a

759^a

15–7208

Synovial fluid

15–8685

Synovial fluid

15–4205

Synovial fluid

200^a

758^a

15–8607

Synovial fluid

188^a

760^a

15–1840

Synovial fluid

217^a

755^a

15–1893

Synovial fluid

15–8808

Synovial fluid

189^a

761^a

Borrelia mayonii

15–0238

Blood

218

182

166

191

201

209

174

193

674

15–0290

Blood

218

182

166

191

202

209

174

193

675

15–1071

Blood

218

182

166

191

201

209

174

193

674

15–3469

Blood

218

182

166

191

201

209

174

193

674

15–4246

Blood

218

182

166

191

201

209

174

193

674

15–5283

Blood

218

182

166

191

201

209

174

193

674

15–5922

Blood

218

182

166

218^a

201

209

174

193

762^a

15–8522

Blood

218

182

166

191

201

209

174

193

674

15–8523

Blood

218

182

166

191

201

209

174

193

674

Borrelia miyamotoi

15–0196

Blood

200

117

151

173

184

191

160

634

15–0228

Blood

200

117

151

173

184

191

160

634

15–4374

Blood

200

117

151

173

184

191

160

634

15–6004

Blood

200

117

151

173

184

191

160

634

15–6731

Blood

200

117

151

173

184

191

160

634

15–7268

Blood

200

117

151

173

184

191

160

634

15–8793

Blood

200

117

151

173

184

191

160

634

16–0683

Blood

200

117

151

173

184

191

160

634

B. hermsii

15–5636

Blood

246^a

206^a

190^a

219^a

226^a

236^a

201^a

218^a

763^a

Candidatus Borrelia johnsonii

clpA

clpX

nifS

pepX

pyrG

recG

rplB

uvrA

15–3581

Blood

247^a

207^a

191^a

220^a

227^a

237^a

202^a

219^a

764^a

Sample ID	Originating State	Specimen Type	clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
Borrelia burgdorferi
15–2664	MN	Blood	18	12	1	11	2	15	1	2	29
15–3449	MN	Blood	4	12	1	11	2	15	1	2	756^a
15–4099	MN	Blood	8	1	1	1	4	16	1	7	32
15–6241	MN	Blood	14	1	5	2	2	1	1	10	530
15–6673	MN	Blood	14	1	5	2	2	1	1	10	530
15–6967	MN	Blood	14	1	5	2	2	1	1	10	530
15–8161	MN	Blood	14	1	5	2	2	1	1	10	530
15–3553	PA	Blood	5	5	4	5	5	5	1	6	8
15–0285	WI	Blood	8	1	1	1	4	16	1	7	32
15–3913	WI	Blood	128	12	1	8	1	6	1	10	758^a
15–4064	WI	Blood	14	1	5	2	2	1	1	10	530
15–1932	IA	CSF	8	1	1	14	2	6	1	10	48
15–0078	MD	Synovial fluid	4	1	1	1	224^a	6	1	217^a	754^a
15–1218	MN	Synovial fluid	24	14	4	18	11	19	1	12	56
16–1191	MN	Synovial fluid	8	1	1	14	2	6	1	10	48
15–2880	MO	Synovial fluid	4	4	3	3	3	3	3	3	19
15–5375	NY	Synovial fluid	4	1	1	1	225^a	6	1	7	759^a
15–7208	NY	Synovial fluid	6	1	5	1	1	7	1	8	7
15–8685	NY	Synovial fluid	1	1	1	1	1	1	1	1	1
15–4205	PA	Synovial fluid	14	1	1	2	1	6	200^a	7	758^a
15–8607	PA	Synovial fluid	5	5	188^a	5	5	5	1	6	760^a
15–1840	VA	Synovial fluid	4	4	3	217^a	3	3	3	3	755^a
15–1893	VA	Synovial fluid	4	1	1	1	1	6	1	7	3
15–8808	VA	Synovial fluid	4	1	189^a	1	1	6	1	7	761^a
Borrelia mayonii
15–0238	MN	Blood	218	182	166	191	201	209	174	193	674
15–0290	MN	Blood	218	182	166	191	202	209	174	193	675
15–1071	MN	Blood	218	182	166	191	201	209	174	193	674
15–3469	WI	Blood	218	182	166	191	201	209	174	193	674
15–4246	MN	Blood	218	182	166	191	201	209	174	193	674
15–5283	MN	Blood	218	182	166	191	201	209	174	193	674
15–5922	MN	Blood	218	182	166	218^a	201	209	174	193	762^a
15–8522	MN	Blood	218	182	166	191	201	209	174	193	674
15–8523	MN	Blood	218	182	166	191	201	209	174	193	674
Borrelia miyamotoi
15–0196	WI	Blood	200	117	151	173	184	191	160	70	634
15–0228	MN	Blood	200	117	151	173	184	191	160	70	634
15–4374	NJ	Blood	200	117	151	173	184	191	160	70	634
15–6004	MN	Blood	200	117	151	173	184	191	160	70	634
15–6731	NJ	Blood	200	117	151	173	184	191	160	70	634
15–7268	NJ	Blood	200	117	151	173	184	191	160	70	634
15–8793	MN	Blood	200	117	151	173	184	191	160	70	634
16–0683	NJ	Blood	200	117	151	173	184	191	160	70	634
B. hermsii
15–5636	MT	Blood	246^a	206^a	190^a	219^a	226^a	236^a	201^a	218^a	763^a
Candidatus Borrelia johnsonii
			clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
15–3581	WI	Blood	247^a	207^a	191^a	220^a	227^a	237^a	202^a	219^a	764^a

Table 1. Multilocus Sequence Typing Allele Profiles and Sequence Types Identified in this Study

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Sample ID	Originating State	Specimen Type	clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
Borrelia burgdorferi
15–2664	MN	Blood	18	12	1	11	2	15	1	2	29
15–3449	MN	Blood	4	12	1	11	2	15	1	2	756^a
15–4099	MN	Blood	8	1	1	1	4	16	1	7	32
15–6241	MN	Blood	14	1	5	2	2	1	1	10	530
15–6673	MN	Blood	14	1	5	2	2	1	1	10	530
15–6967	MN	Blood	14	1	5	2	2	1	1	10	530
15–8161	MN	Blood	14	1	5	2	2	1	1	10	530
15–3553	PA	Blood	5	5	4	5	5	5	1	6	8
15–0285	WI	Blood	8	1	1	1	4	16	1	7	32
15–3913	WI	Blood	128	12	1	8	1	6	1	10	758^a
15–4064	WI	Blood	14	1	5	2	2	1	1	10	530
15–1932	IA	CSF	8	1	1	14	2	6	1	10	48
15–0078	MD	Synovial fluid	4	1	1	1	224^a	6	1	217^a	754^a
15–1218	MN	Synovial fluid	24	14	4	18	11	19	1	12	56
16–1191	MN	Synovial fluid	8	1	1	14	2	6	1	10	48
15–2880	MO	Synovial fluid	4	4	3	3	3	3	3	3	19
15–5375	NY	Synovial fluid	4	1	1	1	225^a	6	1	7	759^a
15–7208	NY	Synovial fluid	6	1	5	1	1	7	1	8	7
15–8685	NY	Synovial fluid	1	1	1	1	1	1	1	1	1
15–4205	PA	Synovial fluid	14	1	1	2	1	6	200^a	7	758^a
15–8607	PA	Synovial fluid	5	5	188^a	5	5	5	1	6	760^a
15–1840	VA	Synovial fluid	4	4	3	217^a	3	3	3	3	755^a
15–1893	VA	Synovial fluid	4	1	1	1	1	6	1	7	3
15–8808	VA	Synovial fluid	4	1	189^a	1	1	6	1	7	761^a
Borrelia mayonii
15–0238	MN	Blood	218	182	166	191	201	209	174	193	674
15–0290	MN	Blood	218	182	166	191	202	209	174	193	675
15–1071	MN	Blood	218	182	166	191	201	209	174	193	674
15–3469	WI	Blood	218	182	166	191	201	209	174	193	674
15–4246	MN	Blood	218	182	166	191	201	209	174	193	674
15–5283	MN	Blood	218	182	166	191	201	209	174	193	674
15–5922	MN	Blood	218	182	166	218^a	201	209	174	193	762^a
15–8522	MN	Blood	218	182	166	191	201	209	174	193	674
15–8523	MN	Blood	218	182	166	191	201	209	174	193	674
Borrelia miyamotoi
15–0196	WI	Blood	200	117	151	173	184	191	160	70	634
15–0228	MN	Blood	200	117	151	173	184	191	160	70	634
15–4374	NJ	Blood	200	117	151	173	184	191	160	70	634
15–6004	MN	Blood	200	117	151	173	184	191	160	70	634
15–6731	NJ	Blood	200	117	151	173	184	191	160	70	634
15–7268	NJ	Blood	200	117	151	173	184	191	160	70	634
15–8793	MN	Blood	200	117	151	173	184	191	160	70	634
16–0683	NJ	Blood	200	117	151	173	184	191	160	70	634
B. hermsii
15–5636	MT	Blood	246^a	206^a	190^a	219^a	226^a	236^a	201^a	218^a	763^a
Candidatus Borrelia johnsonii
			clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
15–3581	WI	Blood	247^a	207^a	191^a	220^a	227^a	237^a	202^a	219^a	764^a

Sample ID	Originating State	Specimen Type	clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
Borrelia burgdorferi
15–2664	MN	Blood	18	12	1	11	2	15	1	2	29
15–3449	MN	Blood	4	12	1	11	2	15	1	2	756^a
15–4099	MN	Blood	8	1	1	1	4	16	1	7	32
15–6241	MN	Blood	14	1	5	2	2	1	1	10	530
15–6673	MN	Blood	14	1	5	2	2	1	1	10	530
15–6967	MN	Blood	14	1	5	2	2	1	1	10	530
15–8161	MN	Blood	14	1	5	2	2	1	1	10	530
15–3553	PA	Blood	5	5	4	5	5	5	1	6	8
15–0285	WI	Blood	8	1	1	1	4	16	1	7	32
15–3913	WI	Blood	128	12	1	8	1	6	1	10	758^a
15–4064	WI	Blood	14	1	5	2	2	1	1	10	530
15–1932	IA	CSF	8	1	1	14	2	6	1	10	48
15–0078	MD	Synovial fluid	4	1	1	1	224^a	6	1	217^a	754^a
15–1218	MN	Synovial fluid	24	14	4	18	11	19	1	12	56
16–1191	MN	Synovial fluid	8	1	1	14	2	6	1	10	48
15–2880	MO	Synovial fluid	4	4	3	3	3	3	3	3	19
15–5375	NY	Synovial fluid	4	1	1	1	225^a	6	1	7	759^a
15–7208	NY	Synovial fluid	6	1	5	1	1	7	1	8	7
15–8685	NY	Synovial fluid	1	1	1	1	1	1	1	1	1
15–4205	PA	Synovial fluid	14	1	1	2	1	6	200^a	7	758^a
15–8607	PA	Synovial fluid	5	5	188^a	5	5	5	1	6	760^a
15–1840	VA	Synovial fluid	4	4	3	217^a	3	3	3	3	755^a
15–1893	VA	Synovial fluid	4	1	1	1	1	6	1	7	3
15–8808	VA	Synovial fluid	4	1	189^a	1	1	6	1	7	761^a
Borrelia mayonii
15–0238	MN	Blood	218	182	166	191	201	209	174	193	674
15–0290	MN	Blood	218	182	166	191	202	209	174	193	675
15–1071	MN	Blood	218	182	166	191	201	209	174	193	674
15–3469	WI	Blood	218	182	166	191	201	209	174	193	674
15–4246	MN	Blood	218	182	166	191	201	209	174	193	674
15–5283	MN	Blood	218	182	166	191	201	209	174	193	674
15–5922	MN	Blood	218	182	166	218^a	201	209	174	193	762^a
15–8522	MN	Blood	218	182	166	191	201	209	174	193	674
15–8523	MN	Blood	218	182	166	191	201	209	174	193	674
Borrelia miyamotoi
15–0196	WI	Blood	200	117	151	173	184	191	160	70	634
15–0228	MN	Blood	200	117	151	173	184	191	160	70	634
15–4374	NJ	Blood	200	117	151	173	184	191	160	70	634
15–6004	MN	Blood	200	117	151	173	184	191	160	70	634
15–6731	NJ	Blood	200	117	151	173	184	191	160	70	634
15–7268	NJ	Blood	200	117	151	173	184	191	160	70	634
15–8793	MN	Blood	200	117	151	173	184	191	160	70	634
16–0683	NJ	Blood	200	117	151	173	184	191	160	70	634
B. hermsii
15–5636	MT	Blood	246^a	206^a	190^a	219^a	226^a	236^a	201^a	218^a	763^a
Candidatus Borrelia johnsonii
			clpA	clpX	nifS	pepX	pyrG	recG	rplB	uvrA	ST
15–3581	WI	Blood	247^a	207^a	191^a	220^a	227^a	237^a	202^a	219^a	764^a

Abbreviation: CSF, cerebrospinal fluid; IA, Iowa; MD, Maryland; MN, Minnesota; MO, Missouri; MT, Missouri; NJ, New Jersey; NY, New York; PA, Pennsylvania; ST, sequence type; VA, Virginia; WI, Wisconsin.

^aDenotes allele or sequence type identified in this study.

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