Baseline Demographic Characteristics of Participants in the Sierra Leone Trial to Introduce a Vaccine Against Ebola Who Reported a Serious Adverse Event, by Vaccination Status
| Characteristic . | Immediate Vaccinated (n = 54) . | Unvaccinated (n = 32) . | Crossover Vaccinated (n = 47) . | Overall (n = 132) . |
|---|---|---|---|---|
| Enrollment site, district | ||||
| COMAHS Library, Western Rural | 12 (22.2) | 1 (3.1) | 3 (6.4) | 16 (12.1) |
| Connaught Hospital, Western Urban | 12 (22.2) | 14 (43.8) | 14 (29.8) | 39 (29.5) |
| Port Loko Government Hospital, Port Loko | 9 (16.7) | 6 (18.8) | 11 (23.4) | 26 (19.7) |
| Saint John of God Hospital–Lunsar, Port Loko | 3 (5.6) | 2 (6.3) | 9 (19.1) | 14 (10.6) |
| Saint John of God Health Center–Kaffu Bullom, Port Loko | 2 (3.7) | 1 (3.1) | 1 (2.1) | 4 (3.0) |
| Holy Spirit Hospital–Makeni, Bombali | 14 (25.9) | 6 (18.8) | 3 (6.4) | 23 (17.4) |
| Magburaka Government Hospital, Tonkolili | 2 (3.7) | 2 (6.3) | 6 (12.8) | 10 (7.6) |
| Age, y | 30 (25–36) | 32 (27–39) | 34 (26–45) | 32 (26–40) |
| Sex | ||||
| Male | 30 (55.6) | 17 (53.1) | 28 (59.6) | 74 (56.1) |
| Female | 24 (44.4) | 15 (46.9) | 19 (40.4) | 58 (43.9) |
| Primary occupation | ||||
| Nursea | 16 (29.6) | 13 (40.6) | 11 (23.4) | 40 (30.3) |
| Allied health professionalb | 2 (3.7) | 1 (3.1) | 0 | 3 (2.3) |
| Physician | 0 | 1 (3.1) | 0 | 1 (0.8) |
| Pharmacist | 0 | 0 | 1 (2.1) | 1 (0.8) |
| Community health worker | 0 | 0 | 2 (4.3) | 2 (1.5) |
| Laboratory worker | 0 | 0 | 3 (6.4) | 3 (2.3) |
| Frontline worker | 28 (51.9) | 13 (40.6) | 17 (36.2) | 58 (43.9) |
| Surveillance worker | 5 (9.3) | 1 (3.1) | 1 (2.1) | 7 (5.3) |
| Other/not reported | 3 (5.6) | 3 (9.4) | 1 (2.1) | 7 (5.3) |
| Work site | ||||
| Not currently working in a health facility | 0 | 0 | 11 (23.4) | 10 (7.6) |
| Ebola facility | 18 (33.3) | 8 (25.0) | 10 (21.3) | 36 (27.3) |
| Hospital | 23 (42.6) | 17 (53.1) | 18 (38.3) | 58 (43.9) |
| Clinic setting | 9 (16.7) | 6 (18.8) | 8 (17.0) | 23 (17.4) |
| Other/not reported | 4 (7.4) | 1 (3.1) | 11 (23.4) | 15 (11.4) |
| Education level | ||||
| None | 5 (9.3) | 3 (9.4) | 6 (12.8) | 14 (10.6) |
| Primary | 4 (7.4) | 2 (6.3) | 2 (4.3) | 8 (6.1) |
| Secondary | 23 (42.6) | 10 (31.3) | 25 (53.2) | 57 (43.2) |
| Tertiary | 21 (38.9) | 16 (50.0) | 12 (25.5) | 49 (37.1) |
| Other/not reported | 1 (1.9) | 1 (3.1) | 2 (4.3) | 4 (3.0) |
| Characteristic . | Immediate Vaccinated (n = 54) . | Unvaccinated (n = 32) . | Crossover Vaccinated (n = 47) . | Overall (n = 132) . |
|---|---|---|---|---|
| Enrollment site, district | ||||
| COMAHS Library, Western Rural | 12 (22.2) | 1 (3.1) | 3 (6.4) | 16 (12.1) |
| Connaught Hospital, Western Urban | 12 (22.2) | 14 (43.8) | 14 (29.8) | 39 (29.5) |
| Port Loko Government Hospital, Port Loko | 9 (16.7) | 6 (18.8) | 11 (23.4) | 26 (19.7) |
| Saint John of God Hospital–Lunsar, Port Loko | 3 (5.6) | 2 (6.3) | 9 (19.1) | 14 (10.6) |
| Saint John of God Health Center–Kaffu Bullom, Port Loko | 2 (3.7) | 1 (3.1) | 1 (2.1) | 4 (3.0) |
| Holy Spirit Hospital–Makeni, Bombali | 14 (25.9) | 6 (18.8) | 3 (6.4) | 23 (17.4) |
| Magburaka Government Hospital, Tonkolili | 2 (3.7) | 2 (6.3) | 6 (12.8) | 10 (7.6) |
| Age, y | 30 (25–36) | 32 (27–39) | 34 (26–45) | 32 (26–40) |
| Sex | ||||
| Male | 30 (55.6) | 17 (53.1) | 28 (59.6) | 74 (56.1) |
| Female | 24 (44.4) | 15 (46.9) | 19 (40.4) | 58 (43.9) |
| Primary occupation | ||||
| Nursea | 16 (29.6) | 13 (40.6) | 11 (23.4) | 40 (30.3) |
| Allied health professionalb | 2 (3.7) | 1 (3.1) | 0 | 3 (2.3) |
| Physician | 0 | 1 (3.1) | 0 | 1 (0.8) |
| Pharmacist | 0 | 0 | 1 (2.1) | 1 (0.8) |
| Community health worker | 0 | 0 | 2 (4.3) | 2 (1.5) |
| Laboratory worker | 0 | 0 | 3 (6.4) | 3 (2.3) |
| Frontline worker | 28 (51.9) | 13 (40.6) | 17 (36.2) | 58 (43.9) |
| Surveillance worker | 5 (9.3) | 1 (3.1) | 1 (2.1) | 7 (5.3) |
| Other/not reported | 3 (5.6) | 3 (9.4) | 1 (2.1) | 7 (5.3) |
| Work site | ||||
| Not currently working in a health facility | 0 | 0 | 11 (23.4) | 10 (7.6) |
| Ebola facility | 18 (33.3) | 8 (25.0) | 10 (21.3) | 36 (27.3) |
| Hospital | 23 (42.6) | 17 (53.1) | 18 (38.3) | 58 (43.9) |
| Clinic setting | 9 (16.7) | 6 (18.8) | 8 (17.0) | 23 (17.4) |
| Other/not reported | 4 (7.4) | 1 (3.1) | 11 (23.4) | 15 (11.4) |
| Education level | ||||
| None | 5 (9.3) | 3 (9.4) | 6 (12.8) | 14 (10.6) |
| Primary | 4 (7.4) | 2 (6.3) | 2 (4.3) | 8 (6.1) |
| Secondary | 23 (42.6) | 10 (31.3) | 25 (53.2) | 57 (43.2) |
| Tertiary | 21 (38.9) | 16 (50.0) | 12 (25.5) | 49 (37.1) |
| Other/not reported | 1 (1.9) | 1 (3.1) | 2 (4.3) | 4 (3.0) |
Data are no. or no. (%) of participants with an SAE or median value (interquartile range).
Abbreviation: COMAHS, College of Medicine and Allied Health Sciences, University of Sierra Leone.
aIncludes nurse, nurse aide, maternal-child health aide, nursing student, midwife, community health nurse, and vaccinator.
bIncludes physiotherapist, dental, medical counselor, and nutritionist.
Baseline Demographic Characteristics of Participants in the Sierra Leone Trial to Introduce a Vaccine Against Ebola Who Reported a Serious Adverse Event, by Vaccination Status
| Characteristic . | Immediate Vaccinated (n = 54) . | Unvaccinated (n = 32) . | Crossover Vaccinated (n = 47) . | Overall (n = 132) . |
|---|---|---|---|---|
| Enrollment site, district | ||||
| COMAHS Library, Western Rural | 12 (22.2) | 1 (3.1) | 3 (6.4) | 16 (12.1) |
| Connaught Hospital, Western Urban | 12 (22.2) | 14 (43.8) | 14 (29.8) | 39 (29.5) |
| Port Loko Government Hospital, Port Loko | 9 (16.7) | 6 (18.8) | 11 (23.4) | 26 (19.7) |
| Saint John of God Hospital–Lunsar, Port Loko | 3 (5.6) | 2 (6.3) | 9 (19.1) | 14 (10.6) |
| Saint John of God Health Center–Kaffu Bullom, Port Loko | 2 (3.7) | 1 (3.1) | 1 (2.1) | 4 (3.0) |
| Holy Spirit Hospital–Makeni, Bombali | 14 (25.9) | 6 (18.8) | 3 (6.4) | 23 (17.4) |
| Magburaka Government Hospital, Tonkolili | 2 (3.7) | 2 (6.3) | 6 (12.8) | 10 (7.6) |
| Age, y | 30 (25–36) | 32 (27–39) | 34 (26–45) | 32 (26–40) |
| Sex | ||||
| Male | 30 (55.6) | 17 (53.1) | 28 (59.6) | 74 (56.1) |
| Female | 24 (44.4) | 15 (46.9) | 19 (40.4) | 58 (43.9) |
| Primary occupation | ||||
| Nursea | 16 (29.6) | 13 (40.6) | 11 (23.4) | 40 (30.3) |
| Allied health professionalb | 2 (3.7) | 1 (3.1) | 0 | 3 (2.3) |
| Physician | 0 | 1 (3.1) | 0 | 1 (0.8) |
| Pharmacist | 0 | 0 | 1 (2.1) | 1 (0.8) |
| Community health worker | 0 | 0 | 2 (4.3) | 2 (1.5) |
| Laboratory worker | 0 | 0 | 3 (6.4) | 3 (2.3) |
| Frontline worker | 28 (51.9) | 13 (40.6) | 17 (36.2) | 58 (43.9) |
| Surveillance worker | 5 (9.3) | 1 (3.1) | 1 (2.1) | 7 (5.3) |
| Other/not reported | 3 (5.6) | 3 (9.4) | 1 (2.1) | 7 (5.3) |
| Work site | ||||
| Not currently working in a health facility | 0 | 0 | 11 (23.4) | 10 (7.6) |
| Ebola facility | 18 (33.3) | 8 (25.0) | 10 (21.3) | 36 (27.3) |
| Hospital | 23 (42.6) | 17 (53.1) | 18 (38.3) | 58 (43.9) |
| Clinic setting | 9 (16.7) | 6 (18.8) | 8 (17.0) | 23 (17.4) |
| Other/not reported | 4 (7.4) | 1 (3.1) | 11 (23.4) | 15 (11.4) |
| Education level | ||||
| None | 5 (9.3) | 3 (9.4) | 6 (12.8) | 14 (10.6) |
| Primary | 4 (7.4) | 2 (6.3) | 2 (4.3) | 8 (6.1) |
| Secondary | 23 (42.6) | 10 (31.3) | 25 (53.2) | 57 (43.2) |
| Tertiary | 21 (38.9) | 16 (50.0) | 12 (25.5) | 49 (37.1) |
| Other/not reported | 1 (1.9) | 1 (3.1) | 2 (4.3) | 4 (3.0) |
| Characteristic . | Immediate Vaccinated (n = 54) . | Unvaccinated (n = 32) . | Crossover Vaccinated (n = 47) . | Overall (n = 132) . |
|---|---|---|---|---|
| Enrollment site, district | ||||
| COMAHS Library, Western Rural | 12 (22.2) | 1 (3.1) | 3 (6.4) | 16 (12.1) |
| Connaught Hospital, Western Urban | 12 (22.2) | 14 (43.8) | 14 (29.8) | 39 (29.5) |
| Port Loko Government Hospital, Port Loko | 9 (16.7) | 6 (18.8) | 11 (23.4) | 26 (19.7) |
| Saint John of God Hospital–Lunsar, Port Loko | 3 (5.6) | 2 (6.3) | 9 (19.1) | 14 (10.6) |
| Saint John of God Health Center–Kaffu Bullom, Port Loko | 2 (3.7) | 1 (3.1) | 1 (2.1) | 4 (3.0) |
| Holy Spirit Hospital–Makeni, Bombali | 14 (25.9) | 6 (18.8) | 3 (6.4) | 23 (17.4) |
| Magburaka Government Hospital, Tonkolili | 2 (3.7) | 2 (6.3) | 6 (12.8) | 10 (7.6) |
| Age, y | 30 (25–36) | 32 (27–39) | 34 (26–45) | 32 (26–40) |
| Sex | ||||
| Male | 30 (55.6) | 17 (53.1) | 28 (59.6) | 74 (56.1) |
| Female | 24 (44.4) | 15 (46.9) | 19 (40.4) | 58 (43.9) |
| Primary occupation | ||||
| Nursea | 16 (29.6) | 13 (40.6) | 11 (23.4) | 40 (30.3) |
| Allied health professionalb | 2 (3.7) | 1 (3.1) | 0 | 3 (2.3) |
| Physician | 0 | 1 (3.1) | 0 | 1 (0.8) |
| Pharmacist | 0 | 0 | 1 (2.1) | 1 (0.8) |
| Community health worker | 0 | 0 | 2 (4.3) | 2 (1.5) |
| Laboratory worker | 0 | 0 | 3 (6.4) | 3 (2.3) |
| Frontline worker | 28 (51.9) | 13 (40.6) | 17 (36.2) | 58 (43.9) |
| Surveillance worker | 5 (9.3) | 1 (3.1) | 1 (2.1) | 7 (5.3) |
| Other/not reported | 3 (5.6) | 3 (9.4) | 1 (2.1) | 7 (5.3) |
| Work site | ||||
| Not currently working in a health facility | 0 | 0 | 11 (23.4) | 10 (7.6) |
| Ebola facility | 18 (33.3) | 8 (25.0) | 10 (21.3) | 36 (27.3) |
| Hospital | 23 (42.6) | 17 (53.1) | 18 (38.3) | 58 (43.9) |
| Clinic setting | 9 (16.7) | 6 (18.8) | 8 (17.0) | 23 (17.4) |
| Other/not reported | 4 (7.4) | 1 (3.1) | 11 (23.4) | 15 (11.4) |
| Education level | ||||
| None | 5 (9.3) | 3 (9.4) | 6 (12.8) | 14 (10.6) |
| Primary | 4 (7.4) | 2 (6.3) | 2 (4.3) | 8 (6.1) |
| Secondary | 23 (42.6) | 10 (31.3) | 25 (53.2) | 57 (43.2) |
| Tertiary | 21 (38.9) | 16 (50.0) | 12 (25.5) | 49 (37.1) |
| Other/not reported | 1 (1.9) | 1 (3.1) | 2 (4.3) | 4 (3.0) |
Data are no. or no. (%) of participants with an SAE or median value (interquartile range).
Abbreviation: COMAHS, College of Medicine and Allied Health Sciences, University of Sierra Leone.
aIncludes nurse, nurse aide, maternal-child health aide, nursing student, midwife, community health nurse, and vaccinator.
bIncludes physiotherapist, dental, medical counselor, and nutritionist.
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