Table 6.

Comparison of the CINP Clinical Guidelines with Other Previously Developed Guidelines for Acute Bipolar Depression

CINP 2017WFSBP 2013aCANMAT and ISBD 2013 NICE 2014 bBAP 2016b
Lurasidone1-2-1
OFC13111
Quetiapine11111
Valproate2321-
Lithium25113
Escitalopram2-3
Fluoxetine23--3
Aripiprazole3-NR--
Imipramine3-4
Phenelzine3--
Carbamazepine453--
Lamotrigine43112
Olanzapine43311
Tranylcypromine4---4
ECT543-5
GabapentinNR-NR--
Leviracetam--NR--
L-thyroxine-4---
ParoxetineNR---3
Risperidone--NR--
rTMSNR----
ZiprasidoneNR-NR--
CINP 2017WFSBP 2013aCANMAT and ISBD 2013 NICE 2014 bBAP 2016b
Lurasidone1-2-1
OFC13111
Quetiapine11111
Valproate2321-
Lithium25113
Escitalopram2-3
Fluoxetine23--3
Aripiprazole3-NR--
Imipramine3-4
Phenelzine3--
Carbamazepine453--
Lamotrigine43112
Olanzapine43311
Tranylcypromine4---4
ECT543-5
GabapentinNR-NR--
Leviracetam--NR--
L-thyroxine-4---
ParoxetineNR---3
Risperidone--NR--
rTMSNR----
ZiprasidoneNR-NR--

Abbreviations: ECT, electroconvulsive therapy; NR, not recommended; OFC, olanzapine-fluoxetine combination; rTMS, repetitive Transcranial Magnetic Stimulation.

The grading is not uniform; instead it reflects the grading utilized by individual guidelines and the table aims only to give an image of how different guidelines prioritize treatment options.

a WFSBP: Recommendation reflects only monotherapy not considering evidence derived from combination treatment (except OFC).

b NICE and BAP ordering is on the basis of line of treatment.

Table 6.

Comparison of the CINP Clinical Guidelines with Other Previously Developed Guidelines for Acute Bipolar Depression

CINP 2017WFSBP 2013aCANMAT and ISBD 2013 NICE 2014 bBAP 2016b
Lurasidone1-2-1
OFC13111
Quetiapine11111
Valproate2321-
Lithium25113
Escitalopram2-3
Fluoxetine23--3
Aripiprazole3-NR--
Imipramine3-4
Phenelzine3--
Carbamazepine453--
Lamotrigine43112
Olanzapine43311
Tranylcypromine4---4
ECT543-5
GabapentinNR-NR--
Leviracetam--NR--
L-thyroxine-4---
ParoxetineNR---3
Risperidone--NR--
rTMSNR----
ZiprasidoneNR-NR--
CINP 2017WFSBP 2013aCANMAT and ISBD 2013 NICE 2014 bBAP 2016b
Lurasidone1-2-1
OFC13111
Quetiapine11111
Valproate2321-
Lithium25113
Escitalopram2-3
Fluoxetine23--3
Aripiprazole3-NR--
Imipramine3-4
Phenelzine3--
Carbamazepine453--
Lamotrigine43112
Olanzapine43311
Tranylcypromine4---4
ECT543-5
GabapentinNR-NR--
Leviracetam--NR--
L-thyroxine-4---
ParoxetineNR---3
Risperidone--NR--
rTMSNR----
ZiprasidoneNR-NR--

Abbreviations: ECT, electroconvulsive therapy; NR, not recommended; OFC, olanzapine-fluoxetine combination; rTMS, repetitive Transcranial Magnetic Stimulation.

The grading is not uniform; instead it reflects the grading utilized by individual guidelines and the table aims only to give an image of how different guidelines prioritize treatment options.

a WFSBP: Recommendation reflects only monotherapy not considering evidence derived from combination treatment (except OFC).

b NICE and BAP ordering is on the basis of line of treatment.

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