Risk for All-Cause and CVD Mortality According to Categories of Plasma 25OHD
| Outcome . | Categories of Plasma 25OHD . | ||
|---|---|---|---|
| Low (<42.5 nmol/L) (n = 779) . | Medium (42.5–100 nmol/L) (n = 3214) . | High (>100 nmol/L) (n = 121) . | |
| All-cause mortality | |||
| Events (n) | 227 | 625 | 43 |
| Incidence rate | 3.12 | 1.94 | 4.08 |
| HR (95% CI) | |||
| Crude | 1.64 (1.41–1.91) | 1.00 | 2.18 (1.60–2.96) |
| Multivariable modela | 1.94 (1.66–2.27) | 1.00 | 1.79 (1.31–2.46) |
| CVD mortality | |||
| Events (n) | 101 | 289 | 17 |
| Incidence rate | 1.39 | 0.90 | 1.61 |
| HR (95% CI) | |||
| Crude | 1.57 (1.25–1.97) | 1.00 | 1.84 (1.13–3.00) |
| Multivariable modela | 1.87 (1.49–2.36) | 1.00 | 1.44 (0.87–2.37) |
| Outcome . | Categories of Plasma 25OHD . | ||
|---|---|---|---|
| Low (<42.5 nmol/L) (n = 779) . | Medium (42.5–100 nmol/L) (n = 3214) . | High (>100 nmol/L) (n = 121) . | |
| All-cause mortality | |||
| Events (n) | 227 | 625 | 43 |
| Incidence rate | 3.12 | 1.94 | 4.08 |
| HR (95% CI) | |||
| Crude | 1.64 (1.41–1.91) | 1.00 | 2.18 (1.60–2.96) |
| Multivariable modela | 1.94 (1.66–2.27) | 1.00 | 1.79 (1.31–2.46) |
| CVD mortality | |||
| Events (n) | 101 | 289 | 17 |
| Incidence rate | 1.39 | 0.90 | 1.61 |
| HR (95% CI) | |||
| Crude | 1.57 (1.25–1.97) | 1.00 | 1.84 (1.13–3.00) |
| Multivariable modela | 1.87 (1.49–2.36) | 1.00 | 1.44 (0.87–2.37) |
25OHD refers to sum of 25-hydroxyvitamin D2 and D3 (nmol/L). Incidence rate is per 100 person-years.
Multivariable model (n = 4109) includes study site, age, sex, smoking, body mass index, systolic blood pressure, and eGFR.
Risk for All-Cause and CVD Mortality According to Categories of Plasma 25OHD
| Outcome . | Categories of Plasma 25OHD . | ||
|---|---|---|---|
| Low (<42.5 nmol/L) (n = 779) . | Medium (42.5–100 nmol/L) (n = 3214) . | High (>100 nmol/L) (n = 121) . | |
| All-cause mortality | |||
| Events (n) | 227 | 625 | 43 |
| Incidence rate | 3.12 | 1.94 | 4.08 |
| HR (95% CI) | |||
| Crude | 1.64 (1.41–1.91) | 1.00 | 2.18 (1.60–2.96) |
| Multivariable modela | 1.94 (1.66–2.27) | 1.00 | 1.79 (1.31–2.46) |
| CVD mortality | |||
| Events (n) | 101 | 289 | 17 |
| Incidence rate | 1.39 | 0.90 | 1.61 |
| HR (95% CI) | |||
| Crude | 1.57 (1.25–1.97) | 1.00 | 1.84 (1.13–3.00) |
| Multivariable modela | 1.87 (1.49–2.36) | 1.00 | 1.44 (0.87–2.37) |
| Outcome . | Categories of Plasma 25OHD . | ||
|---|---|---|---|
| Low (<42.5 nmol/L) (n = 779) . | Medium (42.5–100 nmol/L) (n = 3214) . | High (>100 nmol/L) (n = 121) . | |
| All-cause mortality | |||
| Events (n) | 227 | 625 | 43 |
| Incidence rate | 3.12 | 1.94 | 4.08 |
| HR (95% CI) | |||
| Crude | 1.64 (1.41–1.91) | 1.00 | 2.18 (1.60–2.96) |
| Multivariable modela | 1.94 (1.66–2.27) | 1.00 | 1.79 (1.31–2.46) |
| CVD mortality | |||
| Events (n) | 101 | 289 | 17 |
| Incidence rate | 1.39 | 0.90 | 1.61 |
| HR (95% CI) | |||
| Crude | 1.57 (1.25–1.97) | 1.00 | 1.84 (1.13–3.00) |
| Multivariable modela | 1.87 (1.49–2.36) | 1.00 | 1.44 (0.87–2.37) |
25OHD refers to sum of 25-hydroxyvitamin D2 and D3 (nmol/L). Incidence rate is per 100 person-years.
Multivariable model (n = 4109) includes study site, age, sex, smoking, body mass index, systolic blood pressure, and eGFR.
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