| Complication (n) . | Lyme Manifestation (n [%]) . | ||||
|---|---|---|---|---|---|
| Meningitis (n = 53) . | Arthritis (n = 60) . | Carditis (n = 11) . | Multiple Erythema Migrans (n = 14) . | Readmission . | |
| All (25) | 16 (30.2) | 4 (6.7) | 2 (18.2) | 3 (21.4) | 6 |
| PICC complications (10) | |||||
| Mechanical | 5 | 0 | 1 | 0 | 0 |
| Infectious | 3 | 0 | 0 | 1 | 2 |
| Adverse drug reactions | |||||
| Oral doxycycline (7) | |||||
| IgE/non-IgE reactions | 1 | 0 | 0 | 0 | 1 |
| Gastrointestinal effects | 2 | 2 | 0 | 0 | 0 |
| Pseudotumor cerebri | 1 | 0 | 1 | 0 | 2 |
| Oral amoxicillin (2) | |||||
| IgE/non-IgE reactions | 0 | 0 | 0 | 1 | 0 |
| Gastrointestinal effects | 0 | 1 | 0 | 0 | 0 |
| IV antibiotics (6) | |||||
| IgE/non-IgE reactions | 4 | 1 | 0 | 1 | 1 |
| Complication (n) . | Lyme Manifestation (n [%]) . | ||||
|---|---|---|---|---|---|
| Meningitis (n = 53) . | Arthritis (n = 60) . | Carditis (n = 11) . | Multiple Erythema Migrans (n = 14) . | Readmission . | |
| All (25) | 16 (30.2) | 4 (6.7) | 2 (18.2) | 3 (21.4) | 6 |
| PICC complications (10) | |||||
| Mechanical | 5 | 0 | 1 | 0 | 0 |
| Infectious | 3 | 0 | 0 | 1 | 2 |
| Adverse drug reactions | |||||
| Oral doxycycline (7) | |||||
| IgE/non-IgE reactions | 1 | 0 | 0 | 0 | 1 |
| Gastrointestinal effects | 2 | 2 | 0 | 0 | 0 |
| Pseudotumor cerebri | 1 | 0 | 1 | 0 | 2 |
| Oral amoxicillin (2) | |||||
| IgE/non-IgE reactions | 0 | 0 | 0 | 1 | 0 |
| Gastrointestinal effects | 0 | 1 | 0 | 0 | 0 |
| IV antibiotics (6) | |||||
| IgE/non-IgE reactions | 4 | 1 | 0 | 1 | 1 |
Abbreviations: IgE, immunoglobulin E; IV, intravenous (parenteral) PICC; peripherally inserted central catheter; PO, per os (oral).
aDefined as adverse drug reactions and central venous catheter complications that led to harm to the patient or need for medical attention. All patients on IV therapy received ceftriaxone.
| Complication (n) . | Lyme Manifestation (n [%]) . | ||||
|---|---|---|---|---|---|
| Meningitis (n = 53) . | Arthritis (n = 60) . | Carditis (n = 11) . | Multiple Erythema Migrans (n = 14) . | Readmission . | |
| All (25) | 16 (30.2) | 4 (6.7) | 2 (18.2) | 3 (21.4) | 6 |
| PICC complications (10) | |||||
| Mechanical | 5 | 0 | 1 | 0 | 0 |
| Infectious | 3 | 0 | 0 | 1 | 2 |
| Adverse drug reactions | |||||
| Oral doxycycline (7) | |||||
| IgE/non-IgE reactions | 1 | 0 | 0 | 0 | 1 |
| Gastrointestinal effects | 2 | 2 | 0 | 0 | 0 |
| Pseudotumor cerebri | 1 | 0 | 1 | 0 | 2 |
| Oral amoxicillin (2) | |||||
| IgE/non-IgE reactions | 0 | 0 | 0 | 1 | 0 |
| Gastrointestinal effects | 0 | 1 | 0 | 0 | 0 |
| IV antibiotics (6) | |||||
| IgE/non-IgE reactions | 4 | 1 | 0 | 1 | 1 |
| Complication (n) . | Lyme Manifestation (n [%]) . | ||||
|---|---|---|---|---|---|
| Meningitis (n = 53) . | Arthritis (n = 60) . | Carditis (n = 11) . | Multiple Erythema Migrans (n = 14) . | Readmission . | |
| All (25) | 16 (30.2) | 4 (6.7) | 2 (18.2) | 3 (21.4) | 6 |
| PICC complications (10) | |||||
| Mechanical | 5 | 0 | 1 | 0 | 0 |
| Infectious | 3 | 0 | 0 | 1 | 2 |
| Adverse drug reactions | |||||
| Oral doxycycline (7) | |||||
| IgE/non-IgE reactions | 1 | 0 | 0 | 0 | 1 |
| Gastrointestinal effects | 2 | 2 | 0 | 0 | 0 |
| Pseudotumor cerebri | 1 | 0 | 1 | 0 | 2 |
| Oral amoxicillin (2) | |||||
| IgE/non-IgE reactions | 0 | 0 | 0 | 1 | 0 |
| Gastrointestinal effects | 0 | 1 | 0 | 0 | 0 |
| IV antibiotics (6) | |||||
| IgE/non-IgE reactions | 4 | 1 | 0 | 1 | 1 |
Abbreviations: IgE, immunoglobulin E; IV, intravenous (parenteral) PICC; peripherally inserted central catheter; PO, per os (oral).
aDefined as adverse drug reactions and central venous catheter complications that led to harm to the patient or need for medical attention. All patients on IV therapy received ceftriaxone.
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