Interaction Between Vitamin A and Vitamin D Levels for Risk of Tuberculosis Disease
Vitamin A and D Levels . | Case Patients, No./Controls, No. . | Multivariate OR (95% CI)a . | P Value b . |
---|---|---|---|
Both VAD and VDD | 12/9 | 6.38 (1.77–22.97)c | .005 |
VAD without VDD | 12/7 | 24.04 (3.96–145.90)d | <.001 |
No VAD or VDD | 92/443 | 1.00 | … |
Vitamin A and D Levels . | Case Patients, No./Controls, No. . | Multivariate OR (95% CI)a . | P Value b . |
---|---|---|---|
Both VAD and VDD | 12/9 | 6.38 (1.77–22.97)c | .005 |
VAD without VDD | 12/7 | 24.04 (3.96–145.90)d | <.001 |
No VAD or VDD | 92/443 | 1.00 | … |
Abbreviations: CI, confidence interval; OR, odds ratio; VAD, vitamin A deficiency; VDD, vitamin D deficiency.
aAdjusted for matching factors (age and sex), body mass index categories, socioeconomic status, heavy alcohol consumption, tobacco use, isoniazid preventive therapy, tuberculosis history, comorbid disease, self-reported diabetes mellitus, index patient smear status, and presence of >1 tuberculosis case in household.
bP value for interaction = .24
cOR for VAD among household contacts with VDD.
dOR for VAD among household contacts without VDD.
Interaction Between Vitamin A and Vitamin D Levels for Risk of Tuberculosis Disease
Vitamin A and D Levels . | Case Patients, No./Controls, No. . | Multivariate OR (95% CI)a . | P Value b . |
---|---|---|---|
Both VAD and VDD | 12/9 | 6.38 (1.77–22.97)c | .005 |
VAD without VDD | 12/7 | 24.04 (3.96–145.90)d | <.001 |
No VAD or VDD | 92/443 | 1.00 | … |
Vitamin A and D Levels . | Case Patients, No./Controls, No. . | Multivariate OR (95% CI)a . | P Value b . |
---|---|---|---|
Both VAD and VDD | 12/9 | 6.38 (1.77–22.97)c | .005 |
VAD without VDD | 12/7 | 24.04 (3.96–145.90)d | <.001 |
No VAD or VDD | 92/443 | 1.00 | … |
Abbreviations: CI, confidence interval; OR, odds ratio; VAD, vitamin A deficiency; VDD, vitamin D deficiency.
aAdjusted for matching factors (age and sex), body mass index categories, socioeconomic status, heavy alcohol consumption, tobacco use, isoniazid preventive therapy, tuberculosis history, comorbid disease, self-reported diabetes mellitus, index patient smear status, and presence of >1 tuberculosis case in household.
bP value for interaction = .24
cOR for VAD among household contacts with VDD.
dOR for VAD among household contacts without VDD.
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