Table 5.

Interaction Between Vitamin A and Vitamin D Levels for Risk of Tuberculosis Disease

Vitamin A and D LevelsCase Patients, No./Controls, No.Multivariate OR (95% CI)aP Value b
Both VAD and VDD12/96.38 (1.77–22.97)c.005
VAD without VDD12/724.04 (3.96–145.90)d<.001
No VAD or VDD92/4431.00
Vitamin A and D LevelsCase Patients, No./Controls, No.Multivariate OR (95% CI)aP Value b
Both VAD and VDD12/96.38 (1.77–22.97)c.005
VAD without VDD12/724.04 (3.96–145.90)d<.001
No VAD or VDD92/4431.00

Abbreviations: CI, confidence interval; OR, odds ratio; VAD, vitamin A deficiency; VDD, vitamin D deficiency.

aAdjusted for matching factors (age and sex), body mass index categories, socioeconomic status, heavy alcohol consumption, tobacco use, isoniazid preventive therapy, tuberculosis history, comorbid disease, self-reported diabetes mellitus, index patient smear status, and presence of >1 tuberculosis case in household.

bP value for interaction = .24

cOR for VAD among household contacts with VDD.

dOR for VAD among household contacts without VDD.

Table 5.

Interaction Between Vitamin A and Vitamin D Levels for Risk of Tuberculosis Disease

Vitamin A and D LevelsCase Patients, No./Controls, No.Multivariate OR (95% CI)aP Value b
Both VAD and VDD12/96.38 (1.77–22.97)c.005
VAD without VDD12/724.04 (3.96–145.90)d<.001
No VAD or VDD92/4431.00
Vitamin A and D LevelsCase Patients, No./Controls, No.Multivariate OR (95% CI)aP Value b
Both VAD and VDD12/96.38 (1.77–22.97)c.005
VAD without VDD12/724.04 (3.96–145.90)d<.001
No VAD or VDD92/4431.00

Abbreviations: CI, confidence interval; OR, odds ratio; VAD, vitamin A deficiency; VDD, vitamin D deficiency.

aAdjusted for matching factors (age and sex), body mass index categories, socioeconomic status, heavy alcohol consumption, tobacco use, isoniazid preventive therapy, tuberculosis history, comorbid disease, self-reported diabetes mellitus, index patient smear status, and presence of >1 tuberculosis case in household.

bP value for interaction = .24

cOR for VAD among household contacts with VDD.

dOR for VAD among household contacts without VDD.

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