Comparison of Diagnostic Testing in Immunocompromised and Nonimmunocompromised Patients With Central Nervous System Histoplasmosis
| Diagnostic test . | Immunocompromised . | Nonimmunocompromised . | P Value . |
|---|---|---|---|
| Culture | 5/23 (21.7) | 4/24 (16.7) | .9484 |
| Antigen | 22/25 (88) | 17/25 (64) | .0978 |
| ID or CF antibody | 8/21 (38.1) | 14/22 (63.6) | .0716 |
| EIA IgG or IgM antibody | 15/22 (68.2) | 22/23 (95.7) | .0430 |
| Antigen or antibody EIA | 23/25 (92) | 25/25 (100) | .4750 |
| Antigen or antibody ID or CF | 19/20 (95) | 20/22 (90.9) | .9326 |
| Diagnostic test . | Immunocompromised . | Nonimmunocompromised . | P Value . |
|---|---|---|---|
| Culture | 5/23 (21.7) | 4/24 (16.7) | .9484 |
| Antigen | 22/25 (88) | 17/25 (64) | .0978 |
| ID or CF antibody | 8/21 (38.1) | 14/22 (63.6) | .0716 |
| EIA IgG or IgM antibody | 15/22 (68.2) | 22/23 (95.7) | .0430 |
| Antigen or antibody EIA | 23/25 (92) | 25/25 (100) | .4750 |
| Antigen or antibody ID or CF | 19/20 (95) | 20/22 (90.9) | .9326 |
Abbreviations: CF, complement fixation; EIA, enzyme immunoassay; ID, immunodiffusion; IgG, immunoglobulin G; IgM, immunoglobulin M.
Comparison of Diagnostic Testing in Immunocompromised and Nonimmunocompromised Patients With Central Nervous System Histoplasmosis
| Diagnostic test . | Immunocompromised . | Nonimmunocompromised . | P Value . |
|---|---|---|---|
| Culture | 5/23 (21.7) | 4/24 (16.7) | .9484 |
| Antigen | 22/25 (88) | 17/25 (64) | .0978 |
| ID or CF antibody | 8/21 (38.1) | 14/22 (63.6) | .0716 |
| EIA IgG or IgM antibody | 15/22 (68.2) | 22/23 (95.7) | .0430 |
| Antigen or antibody EIA | 23/25 (92) | 25/25 (100) | .4750 |
| Antigen or antibody ID or CF | 19/20 (95) | 20/22 (90.9) | .9326 |
| Diagnostic test . | Immunocompromised . | Nonimmunocompromised . | P Value . |
|---|---|---|---|
| Culture | 5/23 (21.7) | 4/24 (16.7) | .9484 |
| Antigen | 22/25 (88) | 17/25 (64) | .0978 |
| ID or CF antibody | 8/21 (38.1) | 14/22 (63.6) | .0716 |
| EIA IgG or IgM antibody | 15/22 (68.2) | 22/23 (95.7) | .0430 |
| Antigen or antibody EIA | 23/25 (92) | 25/25 (100) | .4750 |
| Antigen or antibody ID or CF | 19/20 (95) | 20/22 (90.9) | .9326 |
Abbreviations: CF, complement fixation; EIA, enzyme immunoassay; ID, immunodiffusion; IgG, immunoglobulin G; IgM, immunoglobulin M.
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