Comparison of pre- and intraoperative features between three groups of patients categorized according to the preservation solution
| Variable . | HTK (n = 61) . | Celsior (n = 38) . | St Thomas (n = 34) . | P . |
|---|---|---|---|---|
| Recipients | ||||
| Mean age (years) | 47.7 ± 12.7 | 49.1 ± 13.1 | 48.0 ± 12.7 | 0.878 |
| Females | 21 (34.4%) | 9 (23.6%) | 12 (35.2%) | 0.462 |
| Mean weight (kg) | 66.9 ± 14.7 | 66.4 ± 8.7 | 64.5 ± 12.9 | 0.690 |
| PVR (Wood Units) | 2.5 ± 1.2 | 3.0 ± 1.6 | 2.6 ± 1.1 | 0.264 |
| Postcardiotomy shock | 3 (4.9%) | 7 (18.4%) | 4 (11.7%) | 0.228 |
| Status 1 | 12 (19.6%) | 5 (13.1%) | 7 (20.5%) | 0.647 |
| Preoperative IABP | 9 (14.7%) | 1 (2.6%) | 2 (5.8%) | 0.093 |
| Preoperative VA-ECMO | 3 (4.9%) | 0 | 3 (8.8%) | 0.193 |
| Preoperative LVAD | 2 (3.2%) | 2 (5.2%) | 2 (5.8%) | 0.813 |
| Previous cardiac surgery | 17 (27.8%) | 9 (23.6%) | 10 (29.4%) | 0.846 |
| Donors | ||||
| Mean age (years) | 42.6 ± 12.9 | 45.7 ± 13.5 | 43.8 ± 15.1 | 0.536 |
| Donor age ≥60 years | 5 (8.1%) | 8 (21.0%) | 8 (23.5%) | 0.083 |
| Females | 25 (40.9%) | 14 (36.8%) | 16 (47.0%) | 0.678 |
| Mean weight (kg) | 76.0 ± 15.5 | 74.7 ± 11.2 | 74.7 ± 11.0 | 0.845 |
| Mean LOS in ICU (days) | 4.3 ± 5.2 | 4.1 ± 3.7 | 3.9 ± 4.6 | 0.913 |
| No inotropes | 11 (18.0%) | 4 (10.5%) | 0 | 0.028 |
| High-dose inotropes | 1 (1.6%) | 1 (2.6%) | 3 (8.8%) | 0.192 |
| Norepinephrine infusion | 23 (37.7%) | 14 (36.8%) | 14 (41.1%) | 0.922 |
| Recipient and donor aged ≥60 years | 3 (4.9%) | 4 (10.5%) | 2 (5.8%) | 0.542 |
| Female donor/male recipient | 7 (11.4%) | 9 (23.6%) | 7 (20.5%) | 0.248 |
| Weight <30% recipient | 2 (3.2%) | 1 (2.6%) | 0 | 0.577 |
| Transplantation data | ||||
| Mean ischaemic time (min) | 188.6 ± 54.3 | 192.1 ± 48.7 | 182.0 ± 54.6 | 0.714 |
| Mean AXC time (min) | 93.5 ± 25.3 | 104.9 ± 30.6 | 97.5 ± 17.2 | 0.098 |
| Mean CPB time (min) | 218.1 ± 87.3 | 229.1 ± 87.9 | 198.1 ± 48.6 | 0.250 |
| Variable . | HTK (n = 61) . | Celsior (n = 38) . | St Thomas (n = 34) . | P . |
|---|---|---|---|---|
| Recipients | ||||
| Mean age (years) | 47.7 ± 12.7 | 49.1 ± 13.1 | 48.0 ± 12.7 | 0.878 |
| Females | 21 (34.4%) | 9 (23.6%) | 12 (35.2%) | 0.462 |
| Mean weight (kg) | 66.9 ± 14.7 | 66.4 ± 8.7 | 64.5 ± 12.9 | 0.690 |
| PVR (Wood Units) | 2.5 ± 1.2 | 3.0 ± 1.6 | 2.6 ± 1.1 | 0.264 |
| Postcardiotomy shock | 3 (4.9%) | 7 (18.4%) | 4 (11.7%) | 0.228 |
| Status 1 | 12 (19.6%) | 5 (13.1%) | 7 (20.5%) | 0.647 |
| Preoperative IABP | 9 (14.7%) | 1 (2.6%) | 2 (5.8%) | 0.093 |
| Preoperative VA-ECMO | 3 (4.9%) | 0 | 3 (8.8%) | 0.193 |
| Preoperative LVAD | 2 (3.2%) | 2 (5.2%) | 2 (5.8%) | 0.813 |
| Previous cardiac surgery | 17 (27.8%) | 9 (23.6%) | 10 (29.4%) | 0.846 |
| Donors | ||||
| Mean age (years) | 42.6 ± 12.9 | 45.7 ± 13.5 | 43.8 ± 15.1 | 0.536 |
| Donor age ≥60 years | 5 (8.1%) | 8 (21.0%) | 8 (23.5%) | 0.083 |
| Females | 25 (40.9%) | 14 (36.8%) | 16 (47.0%) | 0.678 |
| Mean weight (kg) | 76.0 ± 15.5 | 74.7 ± 11.2 | 74.7 ± 11.0 | 0.845 |
| Mean LOS in ICU (days) | 4.3 ± 5.2 | 4.1 ± 3.7 | 3.9 ± 4.6 | 0.913 |
| No inotropes | 11 (18.0%) | 4 (10.5%) | 0 | 0.028 |
| High-dose inotropes | 1 (1.6%) | 1 (2.6%) | 3 (8.8%) | 0.192 |
| Norepinephrine infusion | 23 (37.7%) | 14 (36.8%) | 14 (41.1%) | 0.922 |
| Recipient and donor aged ≥60 years | 3 (4.9%) | 4 (10.5%) | 2 (5.8%) | 0.542 |
| Female donor/male recipient | 7 (11.4%) | 9 (23.6%) | 7 (20.5%) | 0.248 |
| Weight <30% recipient | 2 (3.2%) | 1 (2.6%) | 0 | 0.577 |
| Transplantation data | ||||
| Mean ischaemic time (min) | 188.6 ± 54.3 | 192.1 ± 48.7 | 182.0 ± 54.6 | 0.714 |
| Mean AXC time (min) | 93.5 ± 25.3 | 104.9 ± 30.6 | 97.5 ± 17.2 | 0.098 |
| Mean CPB time (min) | 218.1 ± 87.3 | 229.1 ± 87.9 | 198.1 ± 48.6 | 0.250 |
High dose inotropes: intravenous dopamine ≥10 μg/kg/min.
PVR: basal pulmonary vascular resistance; IABP: intra-aortic balloon pump; VA-ECMO: veno-arterial extracorporeal membrane oxygenation; LVAD: left ventricular assist device; LOS: length of stay; ICU: intensive care unit; AXC: aortic cross clamping; CPB: cardiopulmonary bypass.
Comparison of pre- and intraoperative features between three groups of patients categorized according to the preservation solution
| Variable . | HTK (n = 61) . | Celsior (n = 38) . | St Thomas (n = 34) . | P . |
|---|---|---|---|---|
| Recipients | ||||
| Mean age (years) | 47.7 ± 12.7 | 49.1 ± 13.1 | 48.0 ± 12.7 | 0.878 |
| Females | 21 (34.4%) | 9 (23.6%) | 12 (35.2%) | 0.462 |
| Mean weight (kg) | 66.9 ± 14.7 | 66.4 ± 8.7 | 64.5 ± 12.9 | 0.690 |
| PVR (Wood Units) | 2.5 ± 1.2 | 3.0 ± 1.6 | 2.6 ± 1.1 | 0.264 |
| Postcardiotomy shock | 3 (4.9%) | 7 (18.4%) | 4 (11.7%) | 0.228 |
| Status 1 | 12 (19.6%) | 5 (13.1%) | 7 (20.5%) | 0.647 |
| Preoperative IABP | 9 (14.7%) | 1 (2.6%) | 2 (5.8%) | 0.093 |
| Preoperative VA-ECMO | 3 (4.9%) | 0 | 3 (8.8%) | 0.193 |
| Preoperative LVAD | 2 (3.2%) | 2 (5.2%) | 2 (5.8%) | 0.813 |
| Previous cardiac surgery | 17 (27.8%) | 9 (23.6%) | 10 (29.4%) | 0.846 |
| Donors | ||||
| Mean age (years) | 42.6 ± 12.9 | 45.7 ± 13.5 | 43.8 ± 15.1 | 0.536 |
| Donor age ≥60 years | 5 (8.1%) | 8 (21.0%) | 8 (23.5%) | 0.083 |
| Females | 25 (40.9%) | 14 (36.8%) | 16 (47.0%) | 0.678 |
| Mean weight (kg) | 76.0 ± 15.5 | 74.7 ± 11.2 | 74.7 ± 11.0 | 0.845 |
| Mean LOS in ICU (days) | 4.3 ± 5.2 | 4.1 ± 3.7 | 3.9 ± 4.6 | 0.913 |
| No inotropes | 11 (18.0%) | 4 (10.5%) | 0 | 0.028 |
| High-dose inotropes | 1 (1.6%) | 1 (2.6%) | 3 (8.8%) | 0.192 |
| Norepinephrine infusion | 23 (37.7%) | 14 (36.8%) | 14 (41.1%) | 0.922 |
| Recipient and donor aged ≥60 years | 3 (4.9%) | 4 (10.5%) | 2 (5.8%) | 0.542 |
| Female donor/male recipient | 7 (11.4%) | 9 (23.6%) | 7 (20.5%) | 0.248 |
| Weight <30% recipient | 2 (3.2%) | 1 (2.6%) | 0 | 0.577 |
| Transplantation data | ||||
| Mean ischaemic time (min) | 188.6 ± 54.3 | 192.1 ± 48.7 | 182.0 ± 54.6 | 0.714 |
| Mean AXC time (min) | 93.5 ± 25.3 | 104.9 ± 30.6 | 97.5 ± 17.2 | 0.098 |
| Mean CPB time (min) | 218.1 ± 87.3 | 229.1 ± 87.9 | 198.1 ± 48.6 | 0.250 |
| Variable . | HTK (n = 61) . | Celsior (n = 38) . | St Thomas (n = 34) . | P . |
|---|---|---|---|---|
| Recipients | ||||
| Mean age (years) | 47.7 ± 12.7 | 49.1 ± 13.1 | 48.0 ± 12.7 | 0.878 |
| Females | 21 (34.4%) | 9 (23.6%) | 12 (35.2%) | 0.462 |
| Mean weight (kg) | 66.9 ± 14.7 | 66.4 ± 8.7 | 64.5 ± 12.9 | 0.690 |
| PVR (Wood Units) | 2.5 ± 1.2 | 3.0 ± 1.6 | 2.6 ± 1.1 | 0.264 |
| Postcardiotomy shock | 3 (4.9%) | 7 (18.4%) | 4 (11.7%) | 0.228 |
| Status 1 | 12 (19.6%) | 5 (13.1%) | 7 (20.5%) | 0.647 |
| Preoperative IABP | 9 (14.7%) | 1 (2.6%) | 2 (5.8%) | 0.093 |
| Preoperative VA-ECMO | 3 (4.9%) | 0 | 3 (8.8%) | 0.193 |
| Preoperative LVAD | 2 (3.2%) | 2 (5.2%) | 2 (5.8%) | 0.813 |
| Previous cardiac surgery | 17 (27.8%) | 9 (23.6%) | 10 (29.4%) | 0.846 |
| Donors | ||||
| Mean age (years) | 42.6 ± 12.9 | 45.7 ± 13.5 | 43.8 ± 15.1 | 0.536 |
| Donor age ≥60 years | 5 (8.1%) | 8 (21.0%) | 8 (23.5%) | 0.083 |
| Females | 25 (40.9%) | 14 (36.8%) | 16 (47.0%) | 0.678 |
| Mean weight (kg) | 76.0 ± 15.5 | 74.7 ± 11.2 | 74.7 ± 11.0 | 0.845 |
| Mean LOS in ICU (days) | 4.3 ± 5.2 | 4.1 ± 3.7 | 3.9 ± 4.6 | 0.913 |
| No inotropes | 11 (18.0%) | 4 (10.5%) | 0 | 0.028 |
| High-dose inotropes | 1 (1.6%) | 1 (2.6%) | 3 (8.8%) | 0.192 |
| Norepinephrine infusion | 23 (37.7%) | 14 (36.8%) | 14 (41.1%) | 0.922 |
| Recipient and donor aged ≥60 years | 3 (4.9%) | 4 (10.5%) | 2 (5.8%) | 0.542 |
| Female donor/male recipient | 7 (11.4%) | 9 (23.6%) | 7 (20.5%) | 0.248 |
| Weight <30% recipient | 2 (3.2%) | 1 (2.6%) | 0 | 0.577 |
| Transplantation data | ||||
| Mean ischaemic time (min) | 188.6 ± 54.3 | 192.1 ± 48.7 | 182.0 ± 54.6 | 0.714 |
| Mean AXC time (min) | 93.5 ± 25.3 | 104.9 ± 30.6 | 97.5 ± 17.2 | 0.098 |
| Mean CPB time (min) | 218.1 ± 87.3 | 229.1 ± 87.9 | 198.1 ± 48.6 | 0.250 |
High dose inotropes: intravenous dopamine ≥10 μg/kg/min.
PVR: basal pulmonary vascular resistance; IABP: intra-aortic balloon pump; VA-ECMO: veno-arterial extracorporeal membrane oxygenation; LVAD: left ventricular assist device; LOS: length of stay; ICU: intensive care unit; AXC: aortic cross clamping; CPB: cardiopulmonary bypass.
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