Table 1.

Baseline Clinical Characteristics and Side Effects Comparing Patients Receiving ECTa and Those Receiving Fluoxetine

ECTFluoxetineP
Variablesnn
Sex, female, n (%)11682 (70.7)12696 (76.2).332a
Age, mean (SD), year11646.9 (12.3)12645.3 (11.0).286b
Age at onset, mean (SD), year11638.1 (12.8)12638.9 (11. 8).636b
Baseline HAMD-17 score, mean (SD)11630.9 (7.0)12631.3 (6.5).602b
Baseline MWSAS score, mean (SD)11623.5 (7.3)12623. 8 (7.9).747b
Baseline SF-36 PCS, mean (SD),10542.4 (9.1)11940.1 (10.6).088b
Baseline SF-36 MCS, mean (SD),10520.5 (7.7)11921.5 (9.0).396b
Employment in the 6 months before the trial, n (%)11619 (16.4)12646 (36.5)<.001a
Anxiolytic/sedative-hypnotic medication used, n (%)116105 (90.5)126113 (89.7).828a
Side effects following treatment11648 (41.4)12621 (16.7)<.001a
Subjective memory impairment, n (%)11624 (20.7)12620 (15.9)0.332a
Nausea/vomiting n (%)11670 (60.3)12621 (16.7)<.001a
Headache n (%)
ECTFluoxetineP
Variablesnn
Sex, female, n (%)11682 (70.7)12696 (76.2).332a
Age, mean (SD), year11646.9 (12.3)12645.3 (11.0).286b
Age at onset, mean (SD), year11638.1 (12.8)12638.9 (11. 8).636b
Baseline HAMD-17 score, mean (SD)11630.9 (7.0)12631.3 (6.5).602b
Baseline MWSAS score, mean (SD)11623.5 (7.3)12623. 8 (7.9).747b
Baseline SF-36 PCS, mean (SD),10542.4 (9.1)11940.1 (10.6).088b
Baseline SF-36 MCS, mean (SD),10520.5 (7.7)11921.5 (9.0).396b
Employment in the 6 months before the trial, n (%)11619 (16.4)12646 (36.5)<.001a
Anxiolytic/sedative-hypnotic medication used, n (%)116105 (90.5)126113 (89.7).828a
Side effects following treatment11648 (41.4)12621 (16.7)<.001a
Subjective memory impairment, n (%)11624 (20.7)12620 (15.9)0.332a
Nausea/vomiting n (%)11670 (60.3)12621 (16.7)<.001a
Headache n (%)

Abbreviations: ECT, electroconvulsive therapy; HAMD-17, 17-item Hamilton Rating Scale for Depression; MCS, mental component summary, lower scores of PCS reflect worse quality of life; MWSAS, Modified Work and Social Adjustment Scale = Work and Social Adjustment Scale (WSAS) without Item 1; PCS, physical component summary, lower scores of PCS reflect worse quality of life;

SF-36, Medical Outcomes Study Short-Form 36.

Bold, statistically significant.

aPearson’s χ2 test

bIndependent t test.

Table 1.

Baseline Clinical Characteristics and Side Effects Comparing Patients Receiving ECTa and Those Receiving Fluoxetine

ECTFluoxetineP
Variablesnn
Sex, female, n (%)11682 (70.7)12696 (76.2).332a
Age, mean (SD), year11646.9 (12.3)12645.3 (11.0).286b
Age at onset, mean (SD), year11638.1 (12.8)12638.9 (11. 8).636b
Baseline HAMD-17 score, mean (SD)11630.9 (7.0)12631.3 (6.5).602b
Baseline MWSAS score, mean (SD)11623.5 (7.3)12623. 8 (7.9).747b
Baseline SF-36 PCS, mean (SD),10542.4 (9.1)11940.1 (10.6).088b
Baseline SF-36 MCS, mean (SD),10520.5 (7.7)11921.5 (9.0).396b
Employment in the 6 months before the trial, n (%)11619 (16.4)12646 (36.5)<.001a
Anxiolytic/sedative-hypnotic medication used, n (%)116105 (90.5)126113 (89.7).828a
Side effects following treatment11648 (41.4)12621 (16.7)<.001a
Subjective memory impairment, n (%)11624 (20.7)12620 (15.9)0.332a
Nausea/vomiting n (%)11670 (60.3)12621 (16.7)<.001a
Headache n (%)
ECTFluoxetineP
Variablesnn
Sex, female, n (%)11682 (70.7)12696 (76.2).332a
Age, mean (SD), year11646.9 (12.3)12645.3 (11.0).286b
Age at onset, mean (SD), year11638.1 (12.8)12638.9 (11. 8).636b
Baseline HAMD-17 score, mean (SD)11630.9 (7.0)12631.3 (6.5).602b
Baseline MWSAS score, mean (SD)11623.5 (7.3)12623. 8 (7.9).747b
Baseline SF-36 PCS, mean (SD),10542.4 (9.1)11940.1 (10.6).088b
Baseline SF-36 MCS, mean (SD),10520.5 (7.7)11921.5 (9.0).396b
Employment in the 6 months before the trial, n (%)11619 (16.4)12646 (36.5)<.001a
Anxiolytic/sedative-hypnotic medication used, n (%)116105 (90.5)126113 (89.7).828a
Side effects following treatment11648 (41.4)12621 (16.7)<.001a
Subjective memory impairment, n (%)11624 (20.7)12620 (15.9)0.332a
Nausea/vomiting n (%)11670 (60.3)12621 (16.7)<.001a
Headache n (%)

Abbreviations: ECT, electroconvulsive therapy; HAMD-17, 17-item Hamilton Rating Scale for Depression; MCS, mental component summary, lower scores of PCS reflect worse quality of life; MWSAS, Modified Work and Social Adjustment Scale = Work and Social Adjustment Scale (WSAS) without Item 1; PCS, physical component summary, lower scores of PCS reflect worse quality of life;

SF-36, Medical Outcomes Study Short-Form 36.

Bold, statistically significant.

aPearson’s χ2 test

bIndependent t test.

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