| Univariate sensitivity analyses . | |||||||
|---|---|---|---|---|---|---|---|
| Model . | Description . | Salpingotomy . | Salpingectomy . | Diff . | 95% CI# . | ICER (95% CI#) . | |
| 0 | Base case | 3319 | 2958 | 361 | 217 | 515 | 40 983 (−130 319 to 145 491) |
| 1* | Thirty per cent higher ward admission costs (€1032 for the first day and €829 for additional days), operation theatre costs (€461 start up and €7,36 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€711). | 4076 | 3645 | 431 | 249 | 624 | 48.852 (−213 473 to 138 799) |
| 2* | Thirty per cent lower ward admission costs (€556 for the first day and €447 for additional days), operation theatre costs (€249 start up and €4,0 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€383). | 2562 | 2270 | 292 | 166 | 430 | 33 113 (−2 146 449 to 118 570) |
| Scenario analyses | |||||||
| Model | Scenario | Salpingotomy | Salpingectomy | Diff | 95% CI# | ICER (95% CI#) | |
| 3* | Surgery in day care admission (€251), instead of ward admission until operation theatre available.^ | 2052 | 1754 | 297 | 169 | 437 | 33 730 (−149 544 to 124 372) |
| 4* | Replace disposable bipolar cutting forceps (€343) by re-usable bipolar forceps and re-usable scissors at no costs. | 3250 | 2615 | 636 | 478 | 798 | 72 097 (−234 791 to 204 129) |
| 5* | Replace weekly serum hCG follow-up after salpingotomy by one serum hCG measurement and no further follow-up if decline is according to serum hCG clearance curve. No serum hCG measurement after salpingectomy. | 3152 | 2912 | 240 | 100 | 381 | 27 264 (−92 252 to 109 817 |
| 6* | Replace weekly serum hCG follow-up by a home urinary pregnancy test 6 weeks after salpingotomy at no costs for home pregnancy test. No serum hCG measurement after salpingectomy. | 3077 | 2912 | 165 | 12 | 316 | 18 730 (−52 205 to 83 594) |
| Univariate sensitivity analyses . | |||||||
|---|---|---|---|---|---|---|---|
| Model . | Description . | Salpingotomy . | Salpingectomy . | Diff . | 95% CI# . | ICER (95% CI#) . | |
| 0 | Base case | 3319 | 2958 | 361 | 217 | 515 | 40 983 (−130 319 to 145 491) |
| 1* | Thirty per cent higher ward admission costs (€1032 for the first day and €829 for additional days), operation theatre costs (€461 start up and €7,36 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€711). | 4076 | 3645 | 431 | 249 | 624 | 48.852 (−213 473 to 138 799) |
| 2* | Thirty per cent lower ward admission costs (€556 for the first day and €447 for additional days), operation theatre costs (€249 start up and €4,0 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€383). | 2562 | 2270 | 292 | 166 | 430 | 33 113 (−2 146 449 to 118 570) |
| Scenario analyses | |||||||
| Model | Scenario | Salpingotomy | Salpingectomy | Diff | 95% CI# | ICER (95% CI#) | |
| 3* | Surgery in day care admission (€251), instead of ward admission until operation theatre available.^ | 2052 | 1754 | 297 | 169 | 437 | 33 730 (−149 544 to 124 372) |
| 4* | Replace disposable bipolar cutting forceps (€343) by re-usable bipolar forceps and re-usable scissors at no costs. | 3250 | 2615 | 636 | 478 | 798 | 72 097 (−234 791 to 204 129) |
| 5* | Replace weekly serum hCG follow-up after salpingotomy by one serum hCG measurement and no further follow-up if decline is according to serum hCG clearance curve. No serum hCG measurement after salpingectomy. | 3152 | 2912 | 240 | 100 | 381 | 27 264 (−92 252 to 109 817 |
| 6* | Replace weekly serum hCG follow-up by a home urinary pregnancy test 6 weeks after salpingotomy at no costs for home pregnancy test. No serum hCG measurement after salpingectomy. | 3077 | 2912 | 165 | 12 | 316 | 18 730 (−52 205 to 83 594) |
*Scenario calculated in both arms.
#Non-parametric confidence interval based on 1000 bootstrap replications.
^Reference Dutch Costing Guideline (Hakkaart-van Roijen et al., 2010).
| Univariate sensitivity analyses . | |||||||
|---|---|---|---|---|---|---|---|
| Model . | Description . | Salpingotomy . | Salpingectomy . | Diff . | 95% CI# . | ICER (95% CI#) . | |
| 0 | Base case | 3319 | 2958 | 361 | 217 | 515 | 40 983 (−130 319 to 145 491) |
| 1* | Thirty per cent higher ward admission costs (€1032 for the first day and €829 for additional days), operation theatre costs (€461 start up and €7,36 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€711). | 4076 | 3645 | 431 | 249 | 624 | 48.852 (−213 473 to 138 799) |
| 2* | Thirty per cent lower ward admission costs (€556 for the first day and €447 for additional days), operation theatre costs (€249 start up and €4,0 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€383). | 2562 | 2270 | 292 | 166 | 430 | 33 113 (−2 146 449 to 118 570) |
| Scenario analyses | |||||||
| Model | Scenario | Salpingotomy | Salpingectomy | Diff | 95% CI# | ICER (95% CI#) | |
| 3* | Surgery in day care admission (€251), instead of ward admission until operation theatre available.^ | 2052 | 1754 | 297 | 169 | 437 | 33 730 (−149 544 to 124 372) |
| 4* | Replace disposable bipolar cutting forceps (€343) by re-usable bipolar forceps and re-usable scissors at no costs. | 3250 | 2615 | 636 | 478 | 798 | 72 097 (−234 791 to 204 129) |
| 5* | Replace weekly serum hCG follow-up after salpingotomy by one serum hCG measurement and no further follow-up if decline is according to serum hCG clearance curve. No serum hCG measurement after salpingectomy. | 3152 | 2912 | 240 | 100 | 381 | 27 264 (−92 252 to 109 817 |
| 6* | Replace weekly serum hCG follow-up by a home urinary pregnancy test 6 weeks after salpingotomy at no costs for home pregnancy test. No serum hCG measurement after salpingectomy. | 3077 | 2912 | 165 | 12 | 316 | 18 730 (−52 205 to 83 594) |
| Univariate sensitivity analyses . | |||||||
|---|---|---|---|---|---|---|---|
| Model . | Description . | Salpingotomy . | Salpingectomy . | Diff . | 95% CI# . | ICER (95% CI#) . | |
| 0 | Base case | 3319 | 2958 | 361 | 217 | 515 | 40 983 (−130 319 to 145 491) |
| 1* | Thirty per cent higher ward admission costs (€1032 for the first day and €829 for additional days), operation theatre costs (€461 start up and €7,36 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€711). | 4076 | 3645 | 431 | 249 | 624 | 48.852 (−213 473 to 138 799) |
| 2* | Thirty per cent lower ward admission costs (€556 for the first day and €447 for additional days), operation theatre costs (€249 start up and €4,0 per minute) and day care admission costs for methotrexate treatment for persistent trophoblast (€383). | 2562 | 2270 | 292 | 166 | 430 | 33 113 (−2 146 449 to 118 570) |
| Scenario analyses | |||||||
| Model | Scenario | Salpingotomy | Salpingectomy | Diff | 95% CI# | ICER (95% CI#) | |
| 3* | Surgery in day care admission (€251), instead of ward admission until operation theatre available.^ | 2052 | 1754 | 297 | 169 | 437 | 33 730 (−149 544 to 124 372) |
| 4* | Replace disposable bipolar cutting forceps (€343) by re-usable bipolar forceps and re-usable scissors at no costs. | 3250 | 2615 | 636 | 478 | 798 | 72 097 (−234 791 to 204 129) |
| 5* | Replace weekly serum hCG follow-up after salpingotomy by one serum hCG measurement and no further follow-up if decline is according to serum hCG clearance curve. No serum hCG measurement after salpingectomy. | 3152 | 2912 | 240 | 100 | 381 | 27 264 (−92 252 to 109 817 |
| 6* | Replace weekly serum hCG follow-up by a home urinary pregnancy test 6 weeks after salpingotomy at no costs for home pregnancy test. No serum hCG measurement after salpingectomy. | 3077 | 2912 | 165 | 12 | 316 | 18 730 (−52 205 to 83 594) |
*Scenario calculated in both arms.
#Non-parametric confidence interval based on 1000 bootstrap replications.
^Reference Dutch Costing Guideline (Hakkaart-van Roijen et al., 2010).
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
