Table I Open in new tab Cost analysis:...

Unit

Unit cost (euro)

Valuation method (source)

Initial admission

First admission day*

Day

794

Direct costs from academic hospital

Additional hospital stay

Day

638

Direct costs from academic hospital

Laparoscopy start up

Standard associated costs of operation

355

Direct costs from academic hospital

Theatre

Minute

5.66

Direct costs from academic hospital

Conversion to open surgery materials

Material

177

Direct costs from academic hospital

Disposable cutting forceps

Material

343

Direct costs from academic hospital

Blood transfusion

Gift

208

Direct costs from academic hospital

Re-laparoscopy with salpingectomy

Procedure

1450

Direct costs from academic hospital

Post-operatively

Serum hCG measurement order

Measurement

12.90

Dutch costing guideline^{^}

Serum hCG measurement

Measurement

10.36

Dutch Health Authority fares^$

Consultation by telephone

Consultation

Direct costs from academic hospital

Consultation outpatient clinic

Consultation

138

Direct costs from academic hospital

Readmission

Hospital admission

Day

638

Direct costs from academic hospital

Diagnostic laparoscopy*

Procedure

525

Direct costs from academic hospital

Laparoscopic salpingectomy

Procedure

1450

Direct costs from academic hospital

Surgical exploration at trocar site*

Procedure

525

Direct costs from academic hospital

Persistent trophoblast

Systemic methotrexate

Kidney, liver function lab tests

Measurement

Dutch Health Authority fares^$ fares

Methotrexate dosage

Milligram

0.21

Pharmaco therapeutic compass^#

Day care methotrexate

Day

547

Direct costs from academic hospital

Serum hCG measurement order

Measurement

12.90

Dutch costing guideline

Serum hCG measurement

Measurement

10.36

Dutch Health Authority fares^$ fares

Consultation by telephone

Consultation

Direct costs from academic hospital

Salpingectomy

Salpingectomy by laparoscopy

Procedure

1450

Direct costs from academic hospital

Hospital admission

Day

638

Direct costs from academic hospital

Repeat ectopic pregnancy

Laparoscopic salpingotomy (€1750) plus 1 admission day (€794)

Procedure

2544

Direct costs from academic hospital

Laparoscopic salpingectomy (€1450) plus one admission day (€794)

Procedure

2244

Direct costs from academic hospital

Single dose methotrexate

Procedure

697

Direct costs from academic hospital

Multiple dose methotrexate

Procedure

2787

Direct costs from academic hospital

Expectant management

Procedure

200

Direct costs from academic hospital

Table I

Open in new tab

Cost analysis: units of resource use, unit costs, valuation method and volume source.

	Unit	Unit cost (euro)	Valuation method (source)
Initial admission
First admission day*	Day	794	Direct costs from academic hospital
Additional hospital stay	Day	638	Direct costs from academic hospital
Laparoscopy start up	Standard associated costs of operation	355	Direct costs from academic hospital
Theatre	Minute	5.66	Direct costs from academic hospital
Conversion to open surgery materials	Material	177	Direct costs from academic hospital
Disposable cutting forceps	Material	343	Direct costs from academic hospital
Blood transfusion	Gift	208	Direct costs from academic hospital
Re-laparoscopy with salpingectomy	Procedure	1450	Direct costs from academic hospital
Post-operatively
Serum hCG measurement order	Measurement	12.90	Dutch costing guideline^{^}
Serum hCG measurement	Measurement	10.36	Dutch Health Authority fares^$
Consultation by telephone	Consultation	52	Direct costs from academic hospital
Consultation outpatient clinic	Consultation	138	Direct costs from academic hospital
Readmission
Hospital admission	Day	638	Direct costs from academic hospital
Diagnostic laparoscopy*	Procedure	525	Direct costs from academic hospital
Laparoscopic salpingectomy	Procedure	1450	Direct costs from academic hospital
Surgical exploration at trocar site*	Procedure	525	Direct costs from academic hospital
Persistent trophoblast
Systemic methotrexate
Kidney, liver function lab tests	Measurement	20	Dutch Health Authority fares^$ fares
Methotrexate dosage	Milligram	0.21	Pharmaco therapeutic compass^#
Day care methotrexate	Day	547	Direct costs from academic hospital
Serum hCG measurement order	Measurement	12.90	Dutch costing guideline
Serum hCG measurement	Measurement	10.36	Dutch Health Authority fares^$ fares
Consultation by telephone	Consultation	52	Direct costs from academic hospital
Salpingectomy
Salpingectomy by laparoscopy	Procedure	1450	Direct costs from academic hospital
Hospital admission	Day	638	Direct costs from academic hospital
Repeat ectopic pregnancy
Laparoscopic salpingotomy (€1750) plus 1 admission day (€794)	Procedure	2544	Direct costs from academic hospital
Laparoscopic salpingectomy (€1450) plus one admission day (€794)	Procedure	2244	Direct costs from academic hospital
Single dose methotrexate	Procedure	697	Direct costs from academic hospital
Multiple dose methotrexate	Procedure	2787	Direct costs from academic hospital
Expectant management	Procedure	200	Direct costs from academic hospital

	Unit	Unit cost (euro)	Valuation method (source)
Initial admission
First admission day*	Day	794	Direct costs from academic hospital
Additional hospital stay	Day	638	Direct costs from academic hospital
Laparoscopy start up	Standard associated costs of operation	355	Direct costs from academic hospital
Theatre	Minute	5.66	Direct costs from academic hospital
Conversion to open surgery materials	Material	177	Direct costs from academic hospital
Disposable cutting forceps	Material	343	Direct costs from academic hospital
Blood transfusion	Gift	208	Direct costs from academic hospital
Re-laparoscopy with salpingectomy	Procedure	1450	Direct costs from academic hospital
Post-operatively
Serum hCG measurement order	Measurement	12.90	Dutch costing guideline^{^}
Serum hCG measurement	Measurement	10.36	Dutch Health Authority fares^$
Consultation by telephone	Consultation	52	Direct costs from academic hospital
Consultation outpatient clinic	Consultation	138	Direct costs from academic hospital
Readmission
Hospital admission	Day	638	Direct costs from academic hospital
Diagnostic laparoscopy*	Procedure	525	Direct costs from academic hospital
Laparoscopic salpingectomy	Procedure	1450	Direct costs from academic hospital
Surgical exploration at trocar site*	Procedure	525	Direct costs from academic hospital
Persistent trophoblast
Systemic methotrexate
Kidney, liver function lab tests	Measurement	20	Dutch Health Authority fares^$ fares
Methotrexate dosage	Milligram	0.21	Pharmaco therapeutic compass^#
Day care methotrexate	Day	547	Direct costs from academic hospital
Serum hCG measurement order	Measurement	12.90	Dutch costing guideline
Serum hCG measurement	Measurement	10.36	Dutch Health Authority fares^$ fares
Consultation by telephone	Consultation	52	Direct costs from academic hospital
Salpingectomy
Salpingectomy by laparoscopy	Procedure	1450	Direct costs from academic hospital
Hospital admission	Day	638	Direct costs from academic hospital
Repeat ectopic pregnancy
Laparoscopic salpingotomy (€1750) plus 1 admission day (€794)	Procedure	2544	Direct costs from academic hospital
Laparoscopic salpingectomy (€1450) plus one admission day (€794)	Procedure	2244	Direct costs from academic hospital
Single dose methotrexate	Procedure	697	Direct costs from academic hospital
Multiple dose methotrexate	Procedure	2787	Direct costs from academic hospital
Expectant management	Procedure	200	Direct costs from academic hospital

*Duration of surgery mean 30 min.

^{^}Reference Dutch Costing Guideline (Hakkaart-van Roijen et al., 2010).

^#Pharmaco therapeutic compass (College voor Zorgverzekeringen, 2011).

^$Hospital pricelist of Dutch Health Authority 2012 (Nederlandse Zorg Autoriteit, www.nza.nl).

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