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Volume 89, Issue 1, January 2006
TOXICOLOGICAL HIGHLIGHT
The TRPV1 Receptor: Target of Toxicants and Therapeutics
Bellina Veronesi and Marga Oortgiesen
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 1–3, https://doi.org/10.1093/toxsci/kfj034
Review
Development of a Refined Database of Mammalian Relative Potency Estimates for Dioxin-like Compounds
Laurie C. Haws and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 4–30, https://doi.org/10.1093/toxsci/kfi294
Intracellular Signaling Mechanisms of Acetaminophen-Induced Liver Cell Death
Hartmut Jaeschke and Mary Lynn Bajt
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 31–41, https://doi.org/10.1093/toxsci/kfi336
FORUM SERIES
Research Strategies for Safety Evaluation of Nanomaterials, Part IV: Risk Assessment of Nanoparticles
Joyce S. Tsuji and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 42–50, https://doi.org/10.1093/toxsci/kfi339
Forum
Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk
Michael P. Holsapple and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 51–56, https://doi.org/10.1093/toxsci/kfj001
BIOTRANSFORMATION AND TOXICOKINETICS
Characterization of In Vitro Oxidative and Conjugative Metabolic Pathways for Brevetoxin (PbTx-2)
Faisal F. Y. Radwan and John S. Ramsdell
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 57–65, https://doi.org/10.1093/toxsci/kfj013
CARCINOGENICITY
Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
Geoffrey M. Curtin and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 66–74, https://doi.org/10.1093/toxsci/kfi343
The Aryl Hydrocarbon Receptor Directly Regulates Expression of the Potent Mitogen Epiregulin
Rushang D. Patel and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 75–82, https://doi.org/10.1093/toxsci/kfi344
Hexachlorobenzene Is a Tumor Co-carcinogen and Induces Alterations in Insulin-Growth Factors Signaling Pathway in the Rat Mammary Gland
Andrea S. Randi and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 83–92, https://doi.org/10.1093/toxsci/kfj023
ENVIRONMENTAL TOXICOLOGY
Gene Expression Profiles in Rat Liver Treated With Perfluorooctanoic Acid (PFOA)
Keerthi S. Guruge and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 93–107, https://doi.org/10.1093/toxsci/kfj011
Toxic Effects of Fumonisin in Mouse Liver Are Independent of the Peroxisome Proliferator-Activated Receptor α
Kenneth A. Voss and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 108–119, https://doi.org/10.1093/toxsci/kfj019
GENETIC TOXICOLOGY
A Toxicogenomics Approach to Identify New Plausible Epigenetic Mechanisms of Ochratoxin A Carcinogenicity in Rat
M. Marin-Kuan and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 120–134, https://doi.org/10.1093/toxsci/kfj017
IMMUNOTOXIOCOLOGY
Effects of Prenatal Exposure to Cigarette Smoke on Offspring Tumor Susceptibility and Associated Immune Mechanisms
Sheung P. Ng and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 135–144, https://doi.org/10.1093/toxsci/kfj006
Inorganic Mercury Inhibits the Activation of LAT in T-Cell Receptor-Mediated Signal Transduction
Stamatina E. Ziemba and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 145–153, https://doi.org/10.1093/toxsci/kfj029
In Vitro Toxicology
Enhancement of Transformed Foci and Induction of Prostaglandins in Balb/c 3T3 Cells by Palytoxin: In Vitro Model Reproduces Carcinogenic Responses in Animal Models Regarding the Inhibitory Effect of Indomethacin and Reversal of Indomethacin's Effect by Exogenous Prostaglandins
Daishiro Miura and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 154–163, https://doi.org/10.1093/toxsci/kfi342
ERK Activation in Arsenite-Treated G1-Enriched CL3 Cells Contributes to Survival, DNA Repair Inhibition, and Micronucleus Formation
Ju-Pi Li and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 164–172, https://doi.org/10.1093/toxsci/kfj004
Comparison of In Vitro and In Vivo Screening Models for Androgenic and Estrogenic Activities
Edwin Sonneveld and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 173–187, https://doi.org/10.1093/toxsci/kfj009
A Physiologically Based Pharmacokinetic Model of Organophosphate Dermal Absorption
D. van der Merwe and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 188–204, https://doi.org/10.1093/toxsci/kfj014
Preferential Induction of CYP1A1 and CYP1B1 in CCSP-Positive Cells
Han Chang and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 205–213, https://doi.org/10.1093/toxsci/kfj025
Potentiation of Apoptosis by Heat Stress Plus Pesticide Exposure in Stress Resistant Human B-Lymphoma Cells and Its Attenuation through Interaction with Follicular Dendritic Cells: Role for c-Jun N-terminal Kinase Signaling
Stephen E. Bloom and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 214–223, https://doi.org/10.1093/toxsci/kfj021
NEUROTOXICOLOGY
Acrylamide Inhibits Dopamine Uptake in Rat Striatal Synaptic Vesicles
Richard M. LoPachin and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 224–234, https://doi.org/10.1093/toxsci/kfj005
Glutamate Excitotoxicity Is Involved in Cell Death Caused by Tributyltin in Cultured Rat Cortical Neurons
Yusuke Nakatsu and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 235–242, https://doi.org/10.1093/toxsci/kfj007
Sequential Involvement of Distinct Glutamate Receptors in Domoic Acid-Induced Neurotoxicity in Rat Mixed Cortical Cultures: Effect of Multiple Dose/Duration Paradigms, Chronological Age, and Repeated Exposure
Shenfeng Qiu and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 243–256, https://doi.org/10.1093/toxsci/kfj008
The Endocrine Disruptor Atrazine Accounts for a Dimorphic Somatostatinergic Neuronal Expression Pattern in Mice
G. Giusi and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 257–264, https://doi.org/10.1093/toxsci/kfj012
Prostaglandin EP1 Receptor Contributes to Excitotoxicity and Focal Ischemic Brain Damage
Abdullah Shafique Ahmad and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 265–270, https://doi.org/10.1093/toxsci/kfj022
Relative Potencies for Acute Effects of Pyrethroids on Motor Function in Rats
M. J. Wolansky and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 271–277, https://doi.org/10.1093/toxsci/kfj020
RESPIRATORY TOXICOLOGY
TRPV1 Antagonists Elevate Cell Surface Populations of Receptor Protein and Exacerbate TRPV1-Mediated Toxicities in Human Lung Epithelial Cells
Mark E. Johansen and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 278–286, https://doi.org/10.1093/toxsci/kfi292
Genotoxic and Inflammatory Effects of Depleted Uranium Particles Inhaled by Rats
Marjorie Monleau and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 287–295, https://doi.org/10.1093/toxsci/kfj010
Biodegradability of Para-aramid Respirable-Sized Fiber-Shaped Particulates (RFP) in Human Lung Cells
D. B. Warheit and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 296–303, https://doi.org/10.1093/toxsci/kfj028
REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY
Testicular Toxicity of Candidate Fuel Additive 1,6-Dimethoxyhexane: Comparison with Several Similar Aliphatic Ethers
Michael G. Wade and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 304–313, https://doi.org/10.1093/toxsci/kfj002
Exposure to Diazinon Alters In Vitro Retinogenesis: Retinospheroid Morphology, Development of Chicken Retinal Cell Types, and Gene Expression
L. E. Paraoanu and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 314–324, https://doi.org/10.1093/toxsci/kfj003
Sub-chronic Exposure to Dibromoacetic Acid, a Water Disinfection By-product, Does Not Affect Gametogenic Potential in Mice
N. M. Weber and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 325–330, https://doi.org/10.1093/toxsci/kfj015
Risk assessment
Dose-Incidence Modeling: Consequences of Linking Quantal Measures of Response to Depletion of Critical Tissue Targets
Melvin E. Andersen and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 331–337, https://doi.org/10.1093/toxsci/kfj024
SAFETY EVALUATION
Toxicity and Tissue Distribution of Magnetic Nanoparticles in Mice
Jun Sung Kim and others
Toxicological Sciences, Volume 89, Issue 1, January 2006, Pages 338–347, https://doi.org/10.1093/toxsci/kfj027
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