Volume 74, Issue 2, August 2003

Editorial

Endocrine Disrupters: The Need for a Refocused Vision

Terri Damstra

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 231–232, https://doi.org/10.1093/toxsci/kfg168

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Erratum

ERRATUM

Toxicological Sciences, Volume 74, Issue 2, August 2003, Page 231, https://doi.org/10.1093/oxfordjournals.toxsci.a007488

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TOXICOLOGICAL HIGHLIGHT

The Tg.AC Mouse Model Passes Test by Failing to Respond

Ronald E. Cannon

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 233–234, https://doi.org/10.1093/toxsci/kfg170

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Review

Shrinking the Biologic World—Nanobiotechnologies for Toxicology

Thomas J. Zieziulewicz and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 235–244, https://doi.org/10.1093/toxsci/kfg108

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Forum

Uncertainties for Endocrine Disrupters: Our View on Progress

George P. Daston and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 245–252, https://doi.org/10.1093/toxsci/kfg105

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BIOTRANSFORMATION AND TOXICOKINETICS

Metabolic Activation of 2-Hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian Hamsters Congenic at the N-Acetyltransferase 2 (NAT2) Locus

Adrian J. Fretland and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 253–259, https://doi.org/10.1093/toxsci/kfg133

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CARCINOGENICITY

Selection of Drugs to Test the Specificity of the Tg.AC Assay by Screening for Induction of the gadd153 Promoter in Vitro

Karol L. Thompson and Frank D. Sistare

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 260–270, https://doi.org/10.1093/toxsci/kfg113

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Evaluation of the Tg.AC Assay: Specificity Testing with Three Noncarcinogenic Pharmaceuticals that Induce Selected Stress Gene Promoters in Vitro and the Inhibitory Effects of Solvent Components

Karol L. Thompson and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 271–278, https://doi.org/10.1093/toxsci/kfg141

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Nickel-Induced Histone Hypoacetylation: The Role of Reactive Oxygen Species

Jiuhong Kang and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 279–286, https://doi.org/10.1093/toxsci/kfg137

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Carcinogenicity of Inhaled Vanadium Pentoxide in F344/N Rats and B6C3F₁ Mice

N. B. Ress and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 287–296, https://doi.org/10.1093/toxsci/kfg136

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ENVIRONMENTAL TOXICOLOGY

Activation of PPARα and PPARγ by Environmental Phthalate Monoesters

Christopher H. Hurst and David J. Waxman

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 297–308, https://doi.org/10.1093/toxsci/kfg145

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GENETIC TOXICOLOGY

Comparative Scoring of Micronucleated Reticulocytes in Rat Peripheral Blood by Flow Cytometry and Microscopy

Dorothea K. Torous and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 309–314, https://doi.org/10.1093/toxsci/kfg143

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IMMUNOTOXICOLOGY

Suppressive Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on the High-Affinity Antibody Response in C57BL/6 Mice

Kaoru Inouye and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 315–324, https://doi.org/10.1093/toxsci/kfg132

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Immune Changes during Acute Cold/Restraint Stress-Induced Inhibition of Host Resistance to Listeria

Ling Cao and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 325–334, https://doi.org/10.1093/toxsci/kfg146

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Role of Double-Stranded RNA-Activated Protein Kinase R (PKR) in Deoxynivalenol-Induced Ribotoxic Stress Response

Hui-Ren Zhou and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 335–344, https://doi.org/10.1093/toxsci/kfg148

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IN VITRO TOXICOLOGY AND ALTERNATIVE TESTING

Pyruvate Attenuates Myoglobin in Vitro Toxicity

Monica A. Valentovic and Jennifer Minigh

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 345–351, https://doi.org/10.1093/toxsci/kfg135

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Species-Dependent Variations in the in Vitro Myotoxicity of Death Adder (Acanthophis) Venoms

Janith C. Wickramaratna and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 352–360, https://doi.org/10.1093/toxsci/kfg144

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NEUROTOXICOLOGY

Thimerosal Induces DNA Breaks, Caspase-3 Activation, Membrane Damage, and Cell Death in Cultured Human Neurons and Fibroblasts

David S. Baskin and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 361–368, https://doi.org/10.1093/toxsci/kfg126

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REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY

Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. I: Maternal and Prenatal Evaluations

Julie R. Thibodeaux and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 369–381, https://doi.org/10.1093/toxsci/kfg121

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Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation

Christopher Lau and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 382–392, https://doi.org/10.1093/toxsci/kfg122

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Effects of in Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in the Male Rat

Christopher J. Bowman and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 393–406, https://doi.org/10.1093/toxsci/kfg128

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Effects of in Utero Tributyltin Chloride Exposure in the Rat on Pregnancy Outcome

Adedayo Adeeko and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 407–415, https://doi.org/10.1093/toxsci/kfg131

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Predicting Neonatal Perchlorate Dose and Inhibition of Iodide Uptake in the Rat during Lactation Using Physiologically-Based Pharmacokinetic Modeling

Rebecca A. Clewell and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 416–436, https://doi.org/10.1093/toxsci/kfg147

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RESPIRATORY TOXICOLOGY

Ozone Exposure Enhances Endotoxin-Induced Mucous Cell Metaplasia in Rat Pulmonary Airways

James G. Wagner and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 437–446, https://doi.org/10.1093/toxsci/kfg120

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SYSTEMS TOXICOLOGY

Glutathione Depletion Exacerbates Methylenedianiline Toxicity to Biliary Epithelial Cells and Hepatocytes in Rats

Mary F. Kanz and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 447–456, https://doi.org/10.1093/toxsci/kfg125

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The Coagulation System Contributes to Synergistic Liver Injury from Exposure to Monocrotaline and Bacterial Lipopolysaccharide

Steven B. Yee and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 457–469, https://doi.org/10.1093/toxsci/kfg129

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Gene Expression Analysis of the Acute Phase Response Using a Canine Microarray

M. A. Higgins and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 470–484, https://doi.org/10.1093/toxsci/kfg142

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Letters to the Editor

Letter

Kenny S. Crump and Harvey J. Clewell

Toxicological Sciences, Volume 74, Issue 2, August 2003, Page 485, https://doi.org/10.1093/toxsci/kfg117

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Reply

William J. Waddell

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 485–486, https://doi.org/10.1093/toxsci/kfg118

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Letter

Melvin E. Andersen and others

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 486–487, https://doi.org/10.1093/toxsci/kfg134

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Reply

William J. Waddell

Toxicological Sciences, Volume 74, Issue 2, August 2003, Pages 487–488, https://doi.org/10.1093/toxsci/kfg139

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