Volume 121, Issue 2, June 2011

SOCIETY OF TOXICOLOGY 50TH ANNIVERSARY INVITED CONTRIBUTION

Transgenic Animal Models in Toxicology: Historical Perspectives and Future Outlook

Darrell R. Boverhof and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 207–233, https://doi.org/10.1093/toxsci/kfr075

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BIOTRANSFORMATION AND TOXICOKINETICS

Toxicokinetics of the Flame Retardant Hexabromocyclododecane Alpha: Effect of Dose, Timing, Route, Repeated Exposure, and Metabolism

David Taylor Szabo and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 234–244, https://doi.org/10.1093/toxsci/kfr059

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HIGHLIGHTED ARTICLE:

Individual Variability in the Detoxification of Carcinogenic Arylhydroxylamines in Human Breast

Keelia Rhoads and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 245–256, https://doi.org/10.1093/toxsci/kfr073

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CARCINOGENICITY

Effect of Sodium Arsenite Dose Administered in the Drinking Water on the Urinary Bladder Epithelium of Female Arsenic (+3 Oxidation State) Methyltransferase Knockout Mice

Masanao Yokohira and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 257–266, https://doi.org/10.1093/toxsci/kfr051

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ENDOCRINE TOXICOLOGY

Differential Stimulation Pathways of Progesterone Secretion from Newly Formed Corpora Lutea in Rats Treated with Ethylene Glycol Monomethyl Ether, Sulpiride, or Atrazine

Yoshikazu Taketa and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 267–278, https://doi.org/10.1093/toxsci/kfr062

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ENVIRONMENTAL TOXICOLOGY

Interaction of PFOS and BDE-47 Co-exposure on Thyroid Hormone Levels and TH-Related Gene and Protein Expression in Developing Rat Brains

Faqi Wang and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 279–291, https://doi.org/10.1093/toxsci/kfr068

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Triclosan and Thyroid-Mediated Metamorphosis in Anurans: Differentiating Growth Effects from Thyroid-Driven Metamorphosis in Xenopus laevis

Douglas J. Fort and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 292–302, https://doi.org/10.1093/toxsci/kfr069

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GENETIC TOXICOLOGY

A Transgenic Drosophila Model for Arsenic Methylation Suggests a Metabolic Rationale for Differential Dose-Dependent Toxicity Endpoints

Jorge G. Muñiz Ortiz and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 303–311, https://doi.org/10.1093/toxsci/kfr074

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IMMUNOTOXICOLOGY

Oral Exposure to Drugs with Immune-Adjuvant Potential Induces Hypersensitivity Responses to the Reporter Antigen TNP-OVA

Lydia M. Kwast and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 312–319, https://doi.org/10.1093/toxsci/kfr052

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IN VITRO METHODS AND ALTERNATIVES TO ANIMALS

Bisphenol A Disrupts Steroidogenesis in Human H295R Cells

Xiaowei Zhang and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 320–327, https://doi.org/10.1093/toxsci/kfr061

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Short-Time Gene Expression Response to Valproic Acid and Valproic Acid Analogs in Mouse Embryonic Stem Cells

Måns Jergil and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 328–342, https://doi.org/10.1093/toxsci/kfr070

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MOLECULAR TOXICOLOGY

ABCB1 Protects Kidney Proximal Tubule Cells Against Cadmium-Induced Apoptosis: Roles of Cadmium and Ceramide Transport

Wing-Kee Lee and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 343–356, https://doi.org/10.1093/toxsci/kfr071

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NEUROTOXICOLOGY

Sensitivity of Dopaminergic Neuron Differentiation from Stem Cells to Chronic Low-Dose Methylmercury Exposure

Bastian Zimmer and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 357–367, https://doi.org/10.1093/toxsci/kfr054

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Maneb and Paraquat-Mediated Neurotoxicity: Involvement of Peroxiredoxin/Thioredoxin System

James R. Roede and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 368–375, https://doi.org/10.1093/toxsci/kfr058

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Autophagy Protects Against Aminochrome-Induced Cell Death in Substantia Nigra-Derived Cell Line

Irmgard Paris and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 376–388, https://doi.org/10.1093/toxsci/kfr060

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REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY

Manganese Induces IGF-1 and Cyclooxygenase-2 Gene Expressions in the Basal Hypothalamus during Prepubertal Female Development

Jill K. Hiney and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 389–396, https://doi.org/10.1093/toxsci/kfr057

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Pharmacological Doses of Testosterone Upregulated Androgen Receptor and 3-Beta-Hydroxysteroid Dehydrogenase/Delta-5-Delta-4 Isomerase and Impaired Leydig Cells Steroidogenesis in Adult Rats

Tatjana S. Kostic and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 397–407, https://doi.org/10.1093/toxsci/kfr063

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Risk assessment

A Quantitative Comparison of the Safety Margins in the European Indicative Occupational Exposure Limits and the Derived No-Effect Levels for Workers under REACH

Linda Schenk and Gunnar Johanson

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 408–416, https://doi.org/10.1093/toxsci/kfr056

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SAFETY EVALUATION

Oversulfated Chondroitin Sulfate and OSCS-Contaminated Heparin Cause Dose- and Route-Dependent Hemodynamic Effects in the Rat

Alain Corbier and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 417–427, https://doi.org/10.1093/toxsci/kfr072

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Letters to the Editor

Pathophysiological Relevance of Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells

Hartmut Jaeschke and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 428–430, https://doi.org/10.1093/toxsci/kfr053

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Response to Pathophysiological Relevance of Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells

Anke Van Summeren and others

Toxicological Sciences, Volume 121, Issue 2, June 2011, Pages 431–433, https://doi.org/10.1093/toxsci/kfr055

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Retraction

Retraction

Toxicological Sciences, Volume 121, Issue 2, June 2011, Page NP, https://doi.org/10.1093/toxsci/kfr119

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Standing Materials

TABLE OF CONTENTS

Toxicological Sciences, Volume 121, Issue 2, June 2011, Page NP, https://doi.org/10.1093/toxsci/kfr120

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COVER

COVER

Toxicological Sciences, Volume 121, Issue 2, June 2011, Page NP, https://doi.org/10.1093/toxsci/kfr121

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Standing Materials

EDITORIAL BOARD

Toxicological Sciences, Volume 121, Issue 2, June 2011, Page NP, https://doi.org/10.1093/toxsci/kfr122

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SUBSCRIPTIONS

Toxicological Sciences, Volume 121, Issue 2, June 2011, Page NP, https://doi.org/10.1093/toxsci/kfr123

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