Volume 109, Issue 1, May 2009

TOXICOLOGICAL HIGHLIGHT

Protection against Aflatoxin B₁ in Rat—A New Look at the Link between Toxicity, Carcinogenicity, and Metabolism

Elizabeth M. Ellis

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 1–3, https://doi.org/10.1093/toxsci/kfp052

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Review

Probabilistic Exposure Analysis for Chemical Risk Characterization

Kenneth T. Bogen and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 4–17, https://doi.org/10.1093/toxsci/kfp036

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FORUM SERIES, PART III

A Toxicology for the 21st Century—Mapping the Road Ahead

Thomas Hartung

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 18–23, https://doi.org/10.1093/toxsci/kfp059

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BIOTRANSFORMATION AND TOXICOKINETICS

Nrf2 Activation Enhances Biliary Excretion of Sulfobromophthalein by Inducing Glutathione-S-Transferase Activity

Scott A. Reisman and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 24–30, https://doi.org/10.1093/toxsci/kfp045

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Altered Disposition of Acetaminophen in Nrf2-null and Keap1-knockdown Mice

Scott A. Reisman and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 31–40, https://doi.org/10.1093/toxsci/kfp047

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CARCINOGENICITY

Highlighted Article

Transgenic Expression of Aflatoxin Aldehyde Reductase (AKR7A1) Modulates Aflatoxin B₁ Metabolism but not Hepatic Carcinogenesis in the Rat

Bill D. Roebuck and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 41–49, https://doi.org/10.1093/toxsci/kfp003

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ENDOCRINE TOXICOLOGY

The Aryl Hydrocarbon Receptor Activator Benzo[a]pyrene Enhances Vitamin D₃ Catabolism in Macrophages

Manabu Matsunawa and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 50–58, https://doi.org/10.1093/toxsci/kfp044

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Standard and Molecular NOAELs for Rat Testicular Toxicity Induced by Flutamide

David Rouquié and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 59–65, https://doi.org/10.1093/toxsci/kfp056

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ENVIRONMENTAL TOXICOLOGY

Chicken Embryo Cardiomyocyte Cultures—A New Approach for Studying Effects of Halogenated Aromatic Hydrocarbons in the Avian Heart

Stephanie P. Jones and Sean W. Kennedy

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 66–74, https://doi.org/10.1093/toxsci/kfp039

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Persistent Adverse Effects on Health and Reproduction Caused by Exposure of Zebrafish to 2,3,7,8-Tetrachlorodibenzo-p-dioxin During Early Development and Gonad Differentiation

Tisha C. King Heiden and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 75–87, https://doi.org/10.1093/toxsci/kfp048

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Rapid Sublethal Toxicity Assessment Using Bioluminescent Caenorhabditis elegans, a Novel Whole-Animal Metabolic Biosensor

Cristina Lagido and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 88–95, https://doi.org/10.1093/toxsci/kfp058

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GENETIC TOXICOLOGY

The Mouse Lymphoma Assay Detects Recombination, Deletion, and Aneuploidy

Jianyong Wang and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 96–105, https://doi.org/10.1093/toxsci/kfp037

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IMMUNOTOXICOLOGY

Suppression of Humoral Immunity by Perfluorooctanoic Acid is Independent of Elevated Serum Corticosterone Concentration in Mice

Jamie C. DeWitt and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 106–112, https://doi.org/10.1093/toxsci/kfp040

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Single-Walled and Multi-Walled Carbon Nanotubes Promote Allergic Immune Responses in Mice

Unni C. Nygaard and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 113–123, https://doi.org/10.1093/toxsci/kfp057

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NEUROTOXICOLOGY

Neurovestibular Toxicities of Acrylonitrile and Iminodipropionitrile in Rats: A Comparative Evaluation of Putative Mechanisms and Target Sites

Haseeb Ahmad Khan and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 124–131, https://doi.org/10.1093/toxsci/kfp043

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Developmental Chlorpyrifos and Methyl Parathion Exposure Alters Radial-Arm Maze Performance in Juvenile and Adult Rats

Frank O. Johnson and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 132–142, https://doi.org/10.1093/toxsci/kfp053

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REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY

Mono-(2-ethylhexyl) phthalate Targets Glycogen Debranching Enzyme and Affects Glycogen Metabolism in Rat Testis

Chikanori Kuramori and others

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 143–151, https://doi.org/10.1093/toxsci/kfp041

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RESPIRATORY TOXICOLOGY

Pulmonary Toxicity and Fate of Agglomerated 10 and 40 nm Aluminum Oxyhydroxides following 4-Week Inhalation Exposure of Rats: Toxic Effects are Determined by Agglomerated, not Primary Particle Size

Jürgen Pauluhn

Toxicological Sciences, Volume 109, Issue 1, May 2009, Pages 152–167, https://doi.org/10.1093/toxsci/kfp046

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