Extract

The Forum Section of Toxicological Sciences is designed to include discussions and commentaries on relevant and timely issues facing toxicologists and to provide an interface between toxicology and public policy. In 2004, a series of articles to discuss approaches to carcinogenicity risk assessment was developed which featured contributions from prominent scientists from around the world. The goal for the series of articles was to facilitate the communication of ideas and promote global discussion to enhance the scientific basis for evaluating the cancer risk that chemicals might pose for people. In the present issue of the journal, we initiate the second series of Forum articles which will focus on the development of sound scientific strategies for the safety evaluation and risk assessment of nanomaterials.

Nanomaterials and structures of nanometer size have generated big interest and enthusiasm and even bigger expectations in many fields ranging from biomedical applications to electronics to energy production. While nanotechnology looms large with commercial promise and potential benefit, an equally large issue is the evaluation of potential effects on human and environmental health. A scientifically sound approach for developing safety evaluation strategies and standards is required, and toxicologists must be at the center of this effort. Toxicology must lead the way.

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