Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies Get access

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Dual inhibition of TGFβ2,3 is severely toxic, whereas selective inhibition of TGFβ1, 2, or 3 and dual inhibition of TGFβ1,2 is generally tolerated In mouse and cynomolgus monkey toxicology studies Get access

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Incorporating Metabolic Competence into High-Throughput Profiling Assays Get access

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Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases Get access

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Of Hammers and Nails: Understanding Academic Challenges with “Context of Use” and “Fit for Purpose”

Long-term exposure to silica nanoparticles induces cardiac hypertrophy through the pyroptosis pathway Get access

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Oral exposure to di(2-ethylhexyl) phthalate (DEHP) alters the expression of GATA6, OCT4, and CDX2 in blastocysts and decreases the rate of implantation in a mouse model Get access

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In vitro seizure risk assessment using a microelectrode array and comparison with an in vivo rat study Get access

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Cadmium exposure following early-life respiratory syncytial virus infection promotes lung fibrosis through autophagy inhibition Get access

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Bayesian benchmark dose modeling analysis and derivation of points of departure for female reproductive toxicity following exposure to di(2-ethylhexyl) phthalate (DEHP) − effects on reproductive hormones, folliculogenesis and estrous cyclicity

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ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility Get access

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Representative photomicrographs of microscopic findings in the heart of rat... Get access

Prenatal exposure to environmentally relevant low-dosage dibutyl phthalate reduces placental efficiency in CD-1 mice Get access

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Effect of DBP0.1 exposure on weight gain patterns of pregnant dams. (A) Dai... Get access

Characteristics of contractility in the 3D ECTs and 2D hiPSC-CMs. A) Repres...

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Effect of DBP0.1 exposure on female fertility parameters in control (CT) an... Get access

Effect of DBP0.1 exposure on fetal and placental weight at GD18.5. DBP0.1 e... Get access

Lipid disposition in (A) fetal labyrinth, (B) maternal decidual, and (C) re... Get access