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Journal Article
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Impact of Romosozumab Treatment for 24 Months After Switching from Denosumab: Three Case Reports
Seong Hee Ahn and others
in
JBMR Plus
JBMR Plus, ziaf070, https://doi.org/10.1093/jbmrpl/ziaf070
Published: 23 April 2025
... gains in two cases. These findings suggest that longer romosozumab therapy can have varied effects on BMD and bone turnover bone mineral density bone turnover markers denosumab romosozumab sequential treatment Impact of Romosozumab Treatment for 24 Months After Switching From Denosumab: Three Case...
Journal Article
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Association of Exercise and Race/Ethnicity with Atypical Femur Fracture
Annette L Adams and others
in
JBMR Plus
JBMR Plus, ziaf071, https://doi.org/10.1093/jbmrpl/ziaf071
Published: 23 April 2025
... that accounting for exercise levels did not change the 5-fold greater risk in Asian women. atypical femur fractures fractures osteoporosis treatment bisphosphonates activity levels weight-bearing exercise National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes...
Journal Article
“Dark Corners”: Child Sex Murder, Forensic Expertise, and Protective Treatment in Socialist Czechoslovakia
Andrea Bělehradová and others
Journal of the History of Medicine and Allied Sciences, jraf011, https://doi.org/10.1093/jhmas/jraf011
Published: 22 April 2025
..., we trace changes in medical experts’ understanding of child sex offenders in socialist Czechoslovakia between the late 1950s and mid-1970s. We show that psychiatrists and sexologists discussed forensic evaluation and the need for specialized treatment years before the 1966 case, but therapeutic...
Journal Article
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Treatment of antibiotic-manufacturing wastewater enriches for Aeromonas veronii, a zoonotic antibiotic-resistant emerging pathogen
Xingshuo Wang and others
The ISME Journal, wraf077, https://doi.org/10.1093/ismejo/wraf077
Published: 21 April 2025
... Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Antibiotic-manufacturing wastewater treatment plants primarily target chemical pollutants...
Journal Article
Snakebite cases and treatment outcomes in the Afar region, Ethiopia: a retrospective and prospective study approach
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Abebe M Aga and others
Transactions of The Royal Society of Tropical Medicine and Hygiene, traf043, https://doi.org/10.1093/trstmh/traf043
Published: 18 April 2025
... ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Background Snakebite envenomation remains a public health issue, particularly in rural areas. Quick and accurate case identification, coupled with timely treatment, is essential to prevent...
Journal Article
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Risk factors associated with morbidity and unfavorable treatment outcome in drug-resistant pulmonary tuberculosis: a case-control study
Changshu Li and others
Precision Clinical Medicine, pbaf008, https://doi.org/10.1093/pcmedi/pbaf008
Published: 18 April 2025
... work is properly cited. For commercial re-use, please contact [email protected] Abstract Objectives To determine the risk factors in patients with drug-resistant tuberculosis (DR-TB) and clinical characteristics related to unfavorable anti-TB treatment outcomes. Methods Among...
Journal Article
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Characteristics and outcome of patients with brain metastases from colorectal cancer
Robin van den Borg and others
Neuro-Oncology Practice, npaf040, https://doi.org/10.1093/nop/npaf040
Published: 17 April 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background Despite a generally poor prognosis of patients with brain metastases of colorectal cancer (CRC-BM), local treatment of BM might be beneficial...
Journal Article
Delayed treatment of severe stroke: room for thrombectomy?
Alessandro Bufi and Valeria Caso
European Heart Journal Supplements, Volume 27, Issue Supplement_3, March 2025, Pages iii69–iii72, https://doi.org/10.1093/eurheartjsupp/suaf018
Published: 16 April 2025
...Alessandro Bufi; Valeria Caso Several brain imaging techniques can be utilized to assess the condition and guide treatment decisions in patients presenting to the emergency department with ischaemic stroke more than 6 h after symptom onset. The choice of imaging modality often depends...
Journal Article
Determinants of the use of insecticide-treated nets and intermittent preventive treatment of malaria among pregnant women in Angola
Ai Aoki and others
International Health, ihaf033, https://doi.org/10.1093/inthealth/ihaf033
Published: 16 April 2025
... medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Background The determinants of insecticide-treated nets (ITNs) use and uptake of three doses or more of intermittent preventive treatment with sulfadoxine-pyrimethamine...
Journal Article
EDITOR'S CHOICE
Clinical predictors for efficacy of erenumab for migraine: a Registry for Migraine (REFORM) study
William Kristian Karlsson and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf147, https://doi.org/10.1093/braincomms/fcaf147
Published: 15 April 2025
.... Abstract Erenumab has proven effective for migraine prevention; however, a substantial proportion of people with migraine do not benefit from treatment, and among those who do, there is considerable variability in response. This study aimed to identify clinical predictors of therapeutic response...
Journal Article
Learning From the Gaps: Rethinking Hepatitis C Virus Retreatment for People Who Inject Drugs
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Joanne M Carson and Gregory J Dore
Clinical Infectious Diseases, ciaf083, https://doi.org/10.1093/cid/ciaf083
Published: 15 April 2025
... reinfection treatment failure Australian Government Department of Health and Ageing (See the Major Article by xxx on pages xx–xx.) Despite the availability of curative direct-acting antiviral (DAA) therapies, the hepatitis C virus (HCV) burden in the United States continues to rise. Diagnosis and linkage...
Journal Article
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Deciphering difficult-to-treat psoriatic arthritis (D2T-PsA): insights from an international survey of patients with psoriatic arthritis
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Andre L Ribeiro and others
in
Rheumatology
Rheumatology, keaf207, https://doi.org/10.1093/rheumatology/keaf207
Published: 12 April 2025
... of Psoriasis and Psoriatic Arthritis (GRAPPA) initiated a project aimed at unraveling the reasons for treatment failures in PsA, culminating in the establishment of definitions for Difficult-to-Treat PsA (D2T-PsA) and Complex-to-Manage PsA (C2M-PsA). This study explores patient perspectives on treatment...
Journal Article
Beyond business as usual for lymphatic filariasis mass drug administration in hotspot districts
Dziedzom K de Souza and others
International Health, ihaf039, https://doi.org/10.1093/inthealth/ihaf039
Published: 12 April 2025
... in a hotspot district of Ghana, with 20 years of MDA. Treatment registers documenting participation were used to identify non-participating individuals. Individuals willingly accepting treatment were given the drugs (E&T). Those who refused treatment were offered testing using the filaria test strip (FTS...
Journal Article
Modeling the Potential Impacts of Outpatient Antiviral Treatment in Reducing Influenza-Associated Hospitalizations in the United States
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Sinead E Morris and others
The Journal of Infectious Diseases, jiaf061, https://doi.org/10.1093/infdis/jiaf061
Published: 12 April 2025
.... 2025 This work is written by (a) US Government employee(s) and is in the public domain in the US. Abstract Background Seasonal influenza causes an estimated 120 000 to 710 000 hospitalizations annually in the United States. Treatment with antiviral medications, such as oseltamivir, can reduce...
Journal Article
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A General Form of Covariate Adjustment in Clinical Trials under Covariate-Adaptive Randomization
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Marlena S Bannick and others
in
Biometrika
Biometrika, asaf029, https://doi.org/10.1093/biomet/asaf029
Published: 12 April 2025
... University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) SUMMARY In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies...
Journal Article
Comparative Effectiveness of Propensity Score Estimation Methods for Inverse Probability of Treatment Weighting Analysis with Complex Survey Data: A Simulation Study
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Lihua Li and others
Journal of Survey Statistics and Methodology, smaf003, https://doi.org/10.1093/jssam/smaf003
Published: 12 April 2025
...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Propensity score (PS) methods, including inverse probability of treatment weighting (IPTW) analysis, are increasingly applied to complex survey data in geriatric studies to infer causal effects. However, the comparative effectiveness of various...
Journal Article
Aldosterone-targeted therapies: early implementation in resistant hypertension and chronic kidney disease
Masatake Kobayashi and others
European Heart Journal, ehaf225, https://doi.org/10.1093/eurheartj/ehaf225
Published: 11 April 2025
... unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Graphical Abstract Graphical Abstract Abstract Treatment-resistant hypertension (TRH) often coexists with chronic kidney disease (CKD), and the presence of both conditions increases the risk...
Journal Article
Treatment delays in patients with lung cancer: a retrospective study conducted at the National Cancer Institute of Mexico between 2004 and 2021
Elysse Bautista-González and others
The Oncologist, Volume 30, Issue 4, April 2025, oyae358, https://doi.org/10.1093/oncolo/oyae358
Published: 09 April 2025
...Elysse Bautista-González; Teresa Verenice Muñoz Rocha; Enrique Soto-Perez-de-Celis; Cecilia Vindrola-Padros; Anne Peasey; Hynek Pikhart Patients diagnosed by an external provider had a longer wait before starting treatment, with a median time of 62 days, compared to 16 days for patients diagnosed...
Journal Article
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Clinical characteristics and factors associated with severe outcomes of 1,891 paediatric patients admitted to the referral cholera treatment centres in Lusaka, Zambia, December 2023-March 2024
Nawa Kalima and others
Open Forum Infectious Diseases, ofaf215, https://doi.org/10.1093/ofid/ofaf215
Published: 09 April 2025
... Mweemba; Nathan Kapata; Roma Chilengi; Lloyd Mulenga Abstract Background Zambia declared a cholera outbreak on 18th October 2023 and as at 31th June 2024 had recorded 23,381 cases and 740 deaths. Of the patients seen at the two main Cholera Treatment Centers (CTCs) in the capital...
Journal Article
Opioid and alcohol use disorder medication availability in outpatient care: national estimates & potential policy levers
Alisa B Busch and others
Health Affairs Scholar, Volume 3, Issue 4, April 2025, qxaf040, https://doi.org/10.1093/haschl/qxaf040
Published: 09 April 2025
... Administration's 2022 National Substance Use and Mental Health Services Survey (N-SUMHSS), for outpatient programs (excluding opioid treatment programs) that provided “primarily SUD services” (SUD) or “primarily mental health but also SUD services” (MH/SUD; N = 9921 programs), we identified program...
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