... is properly cited. Abstract Background Readmission following endoscopic endonasal transsphenoidal surgery (EETS) for pituitary neuroendocrine tumor (PitNET) and other sellar pathology is most commonly due to delayed hyponatremia. Studies suggest postoperative fluid restriction (FR) reduces delayed...

... in acromegaly published up to February, 25, 2022 were included in this systematic review. Risk of bias was assessed using a modified Newcastle–Ottawa Scale and Joanna Briggs Institute Critical Appraisal Checklist. Primary treatment modalities included (transsphenoidal) surgery and medical treatment with first...

... insipidus after endoscopic transsphenoidal surgery . Pituitary . 2013 ; 16 ( 4 ): 445 – 451 . 10.1007/s11102-012-0453-1 13 Nemergut   EC , Zuo   Z , Jane   JA , Laws   ER . Predictors of diabetes insipidus after transsphenoidal surgery: a review of 881 patients . J Neurosurg...

... of hyperprolactinemia (ie, medication or nonfunctioning adenomas with mild hyperprolactinemia resulting from stalk compression). The need for written informed consent was waived by the Scientific Committee (research protocol W2018.048). Transsphenoidal surgery (TSS) has long been a last-resort treatment for patients...

... ) growth hormone somatostatin analogues insulin-like growth factor 1 (IGF-1) transsphenoidal surgery Acromegaly is an orphan and debilitating disease calling for specialized management by highly experienced multidisciplinary teams. Surgery is the only curative therapy and is regarded as first-line...

... insights for risk stratification and personalized management of GHomas. pituitary tumor curation combined molecular and clinical biomarkers transsphenoidal surgery REMAH study Spanish Society of Endocrinology and Nutrition (SEEN) Molecular Registry of Pituitary Adenomas Novartis...

... management transsphenoidal surgery conservative management Pituitary apoplexy (PA) is a clinical condition caused by bleeding and/or infarction within a pituitary tumor resulting in sudden tumor enlargement. Compression of the pituitary gland and surrounding structures determines variable clinical...

... transsphenoidal surgery treatment outcomes Pituitary apoplexy (PA) is a relatively rare but well-recognized syndrome caused by rapid hemorrhage and/or infarction of a tumor in the pituitary fossa ( 1 ). PA presents with a constellation of symptoms including headache, nausea, vomiting, visual changes, oculomotor...

... ^{, 8} At diagnosis, 60%-85% of patients with macroadenoma have at least 1 pituitary hormone deficiency. ⁹ If there are indications for treatment, such as visual disturbances, the first-line treatment is transsphenoidal surgery. ¹⁰ Visual impairments frequently improve...

...David T Asuzu; Shyama Bhatt; Diana Nwokoye; Christina Hayes; Michaela Cortes; Raven McGlotten; Meg Keil; Christina Tatsi; Lynnette Nieman; Prashant Chittiboina The requirement for glucocorticoid replacement therapy after transsphenoidal surgery (TSS) depends on the preoperative diagnosis, intra...

... ( 23–28 ). One study demonstrated that the implementation of 1 L/day fluid restriction between POD 4 and POD 8 was successful in decreasing the risk of delayed hyponatremia after transsphenoidal surgery from 12.3% to 0% ( 25 ). A second study showed that patients on fluid restriction to 1 L/day for 7...

... studies are necessary to confirm our findings. acromegaly Cushing’s disease race racial differences transsphenoidal surgery remission Growth hormone (GH) and adrenocorticotropin (ACTH)-secreting pituitary adenomas represent 10% to 20% of all pituitary adenomas [ 1-5 ]. Hormone hypersecretion leads...

... of a novel robotic endoscope holder, developed for transsphenoidal surgery. METHODS Patients were prospectively enrolled for 3 mo at the Neurosurgery Unit of Brescia. Endoscope Robot^® was used to assist during the sphenoidal phase of the approach, tumor removal, and skull base reconstruction...

...Regin Jay Mallari; Jai Deep Thakur; Garni Barkhoudarian; Amy Eisenberg; Amanda Rodriguez; Sarah Rettinger; Pejman Cohan; Lynnette Nieman; Daniel F Kelly Cushing’s disease pituitary adenoma transsphenoidal surgery ACTH salivary cortisol 24-hour urinary free cortisol National Institutes...

... was performed to confirm the presence of GH-secreting pituitary adenoma cells. All patients underwent transsphenoidal surgery (TSS) of their tumors, which was performed by 3 experienced surgeons. Pituitary adenomas were classified based on preoperative MRI and intraoperative findings, according to modified...

... Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Transsphenoidal surgery COVID-19 Postoperative infections Personal protective equipment (PPE) To the Editor: Early in the COVID-19 global pandemic, the neurosurgical and otolaryngology...

... preoperatively to 6 months postoperatively. Pituitary adenoma transsphenoidal surgery outcomes patient counselling Outcomes of surgical procedures are often reported in literature in a clinician-centered fashion. Classic surgical outcome papers primarily report on measures of efficacy, like remission rates...

...; SSA-1, first-generation somatostatin analog (octreotide or lanreotide); SSA-2, second-generation somatostatin analog (pasireotide); TSS, transsphenoidal surgery; ULN, upper limit of normal;. Table 2. Univariate analysis for selection of predictors of early biochemical remission, long-term remission...

... transsphenoidal surgery lanreotide octreotide cabergoline Novartis Oncology Ipsen Pharmaceuticals Acromegaly is a chronic and systemic disease caused in the vast majority of cases by a growth hormone (GH)-secreting pituitary adenoma ( 1 ). Although currently the long-term outlook for patients suffering...

... ) Abstract BACKGROUND Diabetes insipidus (DI) is a recognized transient or permanent complication following transsphenoidal surgery (TSS) for pituitary tumors. OBJECTIVE To describe significant experience with the incidence of DI after TSS, identifying predictive characteristics and describing our...