...-randomized controlled trials that compared therapeutic hypothermia (either whole-body cooling or selective head cooling) with no cooling or standard treatment for HIE (i.e. supportive treatment without cooling). We included infants born at or beyond 35 weeks of gestation, with perinatal asphyxia, and without...

... ) Abstract Background Hypoxia-ischemic encephalopathy (HIE) is one of the most important complications of the newborn period. It is the result of depriving nerve tissue of oxygen and glucose, which may be the result of either hypoxia or ischemia. Objective To assess effect of therapeutic hypothermia...

..., spectroscopy, and diffusion imaging. The potential of these MRI biomarkers in predicting long-term neurodevelopmental outcomes and the probability of epilepsy is also discussed. hypoxic-ischaemic encephalopathy neonatal encephalopathy hypothermia therapeutic hypothermia outcome MRI Hypoxic-ischaemic...

... Therapeutic hypothermia (TH) is a standard of care for neonatal Hypoxic Ischemic Encephalopathy (HIE) in developed countries. Most data come from High income countries (HIC). Recently, experts suggest that the safety and efficacy data on cooling from HIC should not be extrapolated to Low and Middle Income...

.../standard_publication_model ) Table 1 shows the baseline demographics of the recruited babies. phenobarbitone serum levels hypoxic ischemia therapeutic hypothermia Institutional Research Grant of Christian Medical College, Vellore, India The world health organization (WHO) recommends phenobarbitone as the first-line...

.... In this article, we propose a multi-target drug discovery method by the example of therapeutic hypothermia (TH). First, we performed protein structure prediction for all protein targets of each group by AlphaFold2 and RoseTTAFold. Then, QuickVina 2 is used for molecular docking between the proteins and drugs...

... Cardiac arrest Targeted temperature management Therapeutic hypothermia QRS/QTc Hypothermia was increasingly proposed as a neuroprotective therapy in the 1990s, culminating in the publication of two randomized trials in 2002, which showed beneficial effects of therapeutic hypothermia in comatose...

... settings ( Lee et al., 2013 ). Therapeutic hypothermia (HT) is currently the only treatment for NE and is routinely used in high-resource settings ( Tagin et al., 2012 ). While HT is clearly beneficial with a number needed to treat to prevent death or disability of 7 ( Tagin et al...

... and compared perioperative co-morbidities, treatment, and outcomes of encephalopathic newborns who received therapeutic hypothermia, with non-acidotic d-TGA patients. Early delays in motor development, long-term behavioural and neurocognitive deficits are common in d-TGA patients, and neuro-developmental...

... function in the MAP72 group. Haemodynamic monitoring therapeutic hypothermia blood pressure critical care double-blind method out-of-hospital cardiac arrest After resuscitation from out-of-hospital cardiac arrest (OHCA), patients often remain comatose and haemodynamically unstable due to anoxic brain...

... and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Objective To assess the effect of therapeutic hypothermia on the outcome in term neonates...

... ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Moderate therapeutic hypothermia procedures are used in post-cardiac arrest care, while in surgical procedures, lower core temperatures are often utilized to provide cerebral protection...

..., the optimal rate and method of cooling and rewarming, and effects of fever require further study. Targeted temperature management therapeutic hypothermia cardiac arrest Targeted temperature management (TTM) refers to a therapeutic strategy of achieving and maintaining a specific core temperature to improve...

...Brigitte Lemyre; Vann Chau Hypoxic-ischemic encephalopathy therapeutic hypothermia L’encéphalopathie néonatale est un syndrome clinique lié à une perturbation de la fonction neurologique qui se manifeste tôt dans la vie et dont l’incidence est d’environ un à six cas sur 1000 naissances vivantes...

... for both infants with moderate encephalopathy (RR 0.68; 95% CI 0.56 to 0.84), an NNT of 6 (95% CI 4 to 13) and those with severe encephalopathy (RR 0.82; 95% CI 0.72 to 0.93), and an NNT of 7 (95% CI 4 to 17). Therapeutic hypothermia is therefore considered to be the standard of care for infants...

...Melissa Naiman; Andrej Markota; Ahmed Hegazy; John Dingley; Erik Kulstad targeted temperature management therapeutic hypothermia critical care burns refractory fever post-cardiac arrest Abstract Core temperature management is an important aspect of critical care; preventing unintentional...

...), and Scopus on 12 February 2017, and updated these on 21 March 2017. We searched with variants of terms related to “GBS,” “sepsis,” “asphyxia,” therapeutic hypothermia,” and “NE” (Supplementary Materials). Medical subject heading (MeSH) terms were used where possible. Supplementary Table 2 describes the full...

.... In cases of persistent respiratory distress despite cardiac recovery, VA-ECMO should be switched to VV-ECMO [ 4 ]. In our case, VA-ECMO was also switched to VV-ECMO after 3 days to provide support for decreased lung function. Additionally, we implemented therapeutic hypothermia to improve the neurological...

...: [email protected] 2016 Abstract Background: Several low-cost methods are used in resource-limited settings to provide therapeutic hypothermia in asphyxiated neonates. There is inadequate data about their efficacy and safety. Methods: This is a retrospective study comparing two low-cost cooling methods...

... not be scored and was already on mechanical ventilation, mild therapeutic hypothermia (MTH) was initiated, irrespective of early coronary intervention. Haemodynamic instability would preclude MTH. MTH aimed to cool patients to 32–34ºC for approximately 24 hours at the intensive care unit (ICU). Sedation...