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Meeting physical activity and resistance exercise guidelines associated with significantly reduced prevalence of diabetes in older adults
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Chiho Kim and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf109, https://doi.org/10.1093/ageing/afaf109
Published: 26 April 2025
... any. These findings highlight the crucial role of regular physical activity in preventing diabetes amongst older individuals, with the potential for a significant public health impact. diabetes resistance exercise physical activity meeting guideline older adults older people Meeting physical...
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Hepatitis C Treatment Initiation During Hospitalization for People Who Use Drugs: A Narrative Review of the Literature
Jacob Denkins and others
Open Forum Infectious Diseases, ofaf237, https://doi.org/10.1093/ofid/ofaf237
Published: 24 April 2025
... the original work is properly cited. Abstract People who use drugs (PWUD) are increasingly acquiring and transmitting hepatitis C virus (HCV) and being admitted to the hospital for often costly non-HCV related conditions. Traditionally, treatment of HCV has been deferred to the outpatient setting. However...
Journal Article
Association of multimorbidity patterns and order of physical frailty and cognitive impairment occurrence: a prospective cohort study
Shuomin Wang and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf101, https://doi.org/10.1093/ageing/afaf101
Published: 23 April 2025
.... Clinician should be aware of multimorbidity clusters and thus provide more effective strategies for comorbid older adults to prevent the onset of these two geriatric syndromes. multimorbidity pattern physical frailty cognitive impairment latent class analysis older people Changsha Science and Technology...
Journal Article
Development of a core outcome set for clinical trials targeting interventions aiming to improve adherence to appropriate polypharmacy in older people—an international consensus study
Hanadi Al Shaker and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf102, https://doi.org/10.1093/ageing/afaf102
Published: 23 April 2025
... in any medium, provided the original work is properly cited. Abstract Background Medication non-adherence is prevalent in older people taking polypharmacy. Several interventions have been employed to improve adherence in this population. However, inconsistencies in outcomes have impeded comparisons...
Journal Article
Low gait speed is better than frailty and sarcopenia at identifying the risk of disability in older adults
Aline Fernanda de Souza and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf104, https://doi.org/10.1093/ageing/afaf104
Published: 23 April 2025
... of functional decline in older adults. frail older people sarcopenic older people gait speed slowness older people Sao Paulo Research Foundation support Tiago da Silva Alexandre 2018/13917–3 Coordination for the Advancement of Higher Education Personnel 305,338/2023–4 Brazilian National...
Journal Article
The interplay between pain and disease activity: personal models of pain beliefs and emotional representations in children and young people with juvenile idiopathic arthritis in a UK nationwide prospective inception cohort
Danielle C Mountain and others
Journal of Pediatric Psychology, jsaf024, https://doi.org/10.1093/jpepsy/jsaf024
Published: 23 April 2025
..., and perceive less control over their pain. Participants with low pain/high disease had similar pain beliefs compared to those with low pain/low disease. Conclusion This is the first study to compare “personal models” of pain in JIA. Children and young people who experience high pain severity regardless...
Journal Article
A hospital-based special care unit for dementia decreased hospital readmission rates for behaviour while reducing rates of falls and occupational violence across medical wards
Frederick A Graham and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf096, https://doi.org/10.1093/ageing/afaf096
Published: 20 April 2025
... rates across hospital medical wards. hospital behaviours and psychological symptoms of dementia dementia-enabling environment falls occupational violence older people Targeted evidence-based models of care for inpatients with behaviours and psychological symptoms of dementia are lacking...
Journal Article
Prediction models for severe treatment-related toxicities in older adults with cancer: a systematic review
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Wing-Lok Chan and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf095, https://doi.org/10.1093/ageing/afaf095
Published: 20 April 2025
... to improve the prediction of severe TRT in this vulnerable population. prediction models geriatric assessment adverse events chemotherapy cancer geriatric oncology systematic review older people This systematic review analysed 12 studies involving 90,819 participants, identifying 15 prediction models...
Journal Article
Adherence to exercise intervention for community-dwelling older adults with sarcopenia: a systematic review and meta-analysis
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Shuang Wu and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf094, https://doi.org/10.1093/ageing/afaf094
Published: 20 April 2025
... studies incorporated only a small number of BCTs into their exercise interventions. Such an approach may be insufficient to enhance adherence in this population effectively. Future studies with theory-informed interventions to improve adherence in the field of exercise for older people with sarcopenia...
Journal Article
What can we learn from 68 000 clinical frailty scale scores? Evaluating the utility of frailty assessment in emergency departments
Hugh Logan Ellis and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf093, https://doi.org/10.1093/ageing/afaf093
Published: 20 April 2025
... and potentially confounding factors can limit its consistency. Automation to enhance CFS score reliability should be explored as a means to support proactive management. clinical frailty scale (CFS) emergency department (ED) electronic health records (EHRs) frailty assessment older people In 68 067 emergency...
Journal Article
Opportunistic screening for atrial fibrillation among frail older patients, little effort for a high diagnostic yield. Outcomes of the Dutch-GERAF study
Lennaert A R Zwart and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf105, https://doi.org/10.1093/ageing/afaf105
Published: 20 April 2025
... opportunistic screening photoplethysmography eHealth older people An at-home eHealth screening strategy for atrial fibrillation is feasible among frail older people. Adding an electrocardiogram (ECG) to the work-up for frail older people on the emergency department will identify new cases of atrial...
Journal Article
The effects of in-hospital orthogeriatric care on health-related quality of life: a systematic review and meta-analysis
Karin Vleeshouwers and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf106, https://doi.org/10.1093/ageing/afaf106
Published: 20 April 2025
... people systematic review older people This is the first systematic review and meta-analysis to evaluate the effects of in-hospital orthogeriatric care on health-related quality of life (HRQoL). Orthogeriatric care has a small yet statistically significant positive impact on HRQoL. High-quality...
Journal Article
Lifestyle, inflammageing, and poor physical performance in middle-aged and older adults: a prospective cohort study in Taiwan
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Chu-Chih Chen and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf107, https://doi.org/10.1093/ageing/afaf107
Published: 19 April 2025
... in societal events to increase their physical performance. To avoid further deterioration in physical frailty, screening for PPP may be adopted as a standard clinical practice for older adults. conversion frailty physical activity poor physical performance psychosocial health reversion older people...
Journal Article
From biology of ageing to geroscience: where will knowledge take us?
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Aurélie Mailliez and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf098, https://doi.org/10.1093/ageing/afaf098
Published: 19 April 2025
... therapies and aim for healthy ageing. biology ageing geroscience older people The biology of ageing has identified various biological and physiological processes that alter the quality of ageing. Geroscience is a translational research that aims to bridge the gap between fundamental and clinical...
Journal Article
Digital biomarkers for real-life, home-based monitoring of frailty: a systematic review and meta-analysis
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Jundan Huang and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf108, https://doi.org/10.1093/ageing/afaf108
Published: 19 April 2025
... to validate the effectiveness of these digital biomarkers as diagnostic tools or prognostic indicators. frailty digital biomarkers digital phenotyping older adults real-world study systematic review older people Central South University Research Programme of Advanced Interdisciplinary Studies...
Journal Article
Physical activity and protein-intake strategies to prevent sarcopenia in older people
Eunjae Lee and others
International Health, ihae064, https://doi.org/10.1093/inthealth/ihae064
Published: 18 April 2025
... aimed to determine the physical activity level and protein intake of older people with sarcopenia and investigate the adequate protein intake of older people in Korea. Methods A total of 1215 older people were recruited from the ninth Korea National Health and Nutrition Examination Survey...
Journal Article
Quadriceps muscle thickness as measured by point-of-care ultrasound is associated with hospital length of stay among hospitalised older patients
Uyanga Ganbat and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf103, https://doi.org/10.1093/ageing/afaf103
Published: 16 April 2025
... of POCUS for assessing patient outcomes. point-of-care ultrasound muscle thickness muscle ultrasound length of stay older people Muscle thickness (MT), as measured by point-of-care ultrasound, can predict hospital length of stay. A 1 cm increase in MT was associated with approximately two days...
Journal Article
Small vessel disease contributions to acute delirium: a pilot feasibility MRI study
Una Clancy and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf099, https://doi.org/10.1093/ageing/afaf099
Published: 16 April 2025
.... This study indicates acute vascular contributions, including SVD, to both delirium- and non-delirium–related presentations, supporting the need for larger studies. delirium cerebral small vessel diseases cerebrovascular disorders magnetic resonance imaging cognitive dysfunction older people Delirium...
Journal Article
Measuring meaning-based well-being in individuals with dementia: the creation and validation of the well-being in dementia inventory
Zehra B Turel and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf092, https://doi.org/10.1093/ageing/afaf092
Published: 16 April 2025
... and policy, advocating a meaning-based approach to well-being assessments that ensures holistic, personalised care by focusing on key indicators of life quality. dementia eudaimonic meaning based scale validation holistic care older people Introduces Well-being in Dementia Inventory (WiDI) to assess...
Journal Article
Risk-factors and multimorbidity in oral anticoagulant-related intracerebral haemorrhage: a comparison of patients in pivotal trials and real life
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Josefine Grundtvig and others
Age and Ageing, Volume 54, Issue 4, April 2025, afaf091, https://doi.org/10.1093/ageing/afaf091
Published: 16 April 2025
... the importance of recruiting adequate numbers of older people and women to cardio-vascular trials to ensure sufficient safety data to advice prescriptions in these very prevalent sub-groups of patients. intracerebral haemorrhage oral anticoagulants (OAC) stroke direct oral anticoagulant (DOAC) older people...
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