... methicillin-resistant Staphylococcus aureus (MRSA) transmission has traditionally been viewed separately in hospital and community settings, this distinction is increasingly blurred. We used whole-genome sequencing and epidemiologic analyses to characterize the movement of MRSA across...

... of phagocytosis could reveal potential strategies to enhance microbial clearance. PTEN is a lipid/protein phosphatase traditionally recognized as a tumor suppressor. While PTEN inhibits various arms of the innate immune response, its role during Staphylococcus aureus infection remains unclear. We...

... , Octaria   R , Kainer   MA . Methicillin-resistant staphylococcus aureus bloodstream infections and injection drug use, Tennessee, USA, 2015–2017 . Emerg Infect Dis   2020 ; 26 : 446 – 53 . 7 Harris   PA , Taylor   R , Thielke   R , Payne   J , Gonzalez   N , Conde...

... and intravenous gentamicin is recommended [ 1 ]. Abstract Background There remains a lack of consensus regarding the postoperative treatment regimen in patients with native valve Staphylococcus aureus infective endocarditis who undergo surgical valve replacement or repair. Methods We conducted...

... general importance, NE was previously thought to play no role in infections caused by Staphylococcus aureus, one of the leading bacterial pathogens. Here, using transgenic mice deficient in NE and a mouse model of localized skin infection, we demonstrate that NE is in fact needed...

... of this session at a glance. Granuloma formation GPA MPA ANCA neutrophil proteases fatty acids crescentic glomerulonephritis FcγRIIa B cells T cells TSST-1 Staphylococcus aureus AstraZeneca 10.13039/100004325 Rheumatology key messages Sequential MPO-ANCA administration and stimulation...

... by Staphylococcus aureus or Streptococcus pneumoniae is linked to poor clinical outcomes, and serves as a potential marker of declining health status and disease vulnerability [ 11 , 12 ]. Abstract Background Biological ageing, healthcare interactions, and pharmaceutical and environmental...

.... Doxycycline post-exposure prophylaxis (doxy PEP) use was associated with increased colonization with Group A Streptococcus and tetracycline-resistant Staphylococcus aureus. Graphical Abstract Graphical Abstract This graphical abstract is also available at Tidbit: https://tidbitapp.io...

... or species. Specifically, in the airway, nontypeable Haemophilus influenzae (NTHI) predominates and is commonly isolated with one or more of the following co-pathogens with which it forms unique relationships: methicillin-resistant Staphylococcus aureus, Burkholderia cenocepacia, Pseudomonas...

...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Septic pulmonary embolism (SPE) is a rare, life-threatening disease in children. We assessed the clinical, microbiological, radiological, and treatment results of patients who developed SPE due to Staphylococcus aureus (S...

... drug use and hepatitis C, a higher proportion of Staphylococcus aureus infections, and a longer recommended duration of antibiotic therapy. Inpatient MOUD strategy can be found in Table 1 . The MOUD group displayed lower 1-year mortality than the no-MOUD group in direct comparison (6/20 [30...

... the resistance of Staphylococcus aureus (S. aureus) to fusidic acid (FD) in 100 patients with skin and soft tissue infections (SSTIs), revealing susceptibility to FD despite resistance to other antibiotics. Through adaptive laboratory evolution, we developed a highly FD-resistant strain, E10...

...Sean W X Ong; Nick Daneman; Joshua S Davis; Steven Y C Tong; for the Combination Antibiotics for MEthicillin Resistant Staphylococcus aureus (CAMERA2) Study Group; David C Lye; Dafna Yahav; Archana Sud; J Owen Robinson; Jane Nelson; Sophia Archuleta; Matthew A Roberts; Alan Cass; David L Paterson...

... and skin microbiome dysbiosis with predominance of Staphylococcus aureus, which is associated with exacerbating AD skin inflammation. Specific glycosylation patterns of S. aureus cell wall structures amplify skin inflammation through interaction with Langerhans cells (LCs). Nevertheless...

... Staphylococcus aureus and enterococcal infections have suggested that higher doses of daptomycin may be associated with better clinical outcomes. However, optimal daptomycin dosing in methicillin-sensitive S aureus bloodstream infections remains unclear. In this multicentered, retrospective...

... of the mvaA gene were observed, together with changes in bacterial morphology. Conclusion Simvastatin can exert its antimicrobial effect by means of changes in the cell wall associated with the mevalonate pathway. simvastatin Staphylococcus aureus drug repositioning antibacterial agents gene...

... of cerebroside flavuside B from the marine fungus Talaromyces islandicum on the Arg system of Staphylococcus aureus and its cytoprotective effect on human keratinocytes infected with S. aureus. This confirmed the pharmacological potential of this fungal secondary metabolite...

.../ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Identifying risk factors for mortality in patients with Staphylococcus aureus bacteremia (SAB) is crucial due to its high fatality. However, data...

... that the editors consider relevant to the content of the manuscript have been disclosed. 31 08 2024 19 12 2024 20 12 2024 15 01 2025 doxycycline postexposure prophylaxis doxy-PEP Staphylococcus aureus Limitations to this study include using HIV positivity and PrEP as a proxy...

...), 41% (n = 698/1703), and 29.5% (n = 503/1703), respectively. Table 1. Demographic and Clinical Characteristics of Patients With Staphylococcus aureus Bacteremia According to Mode of Acquisition Characteristic All Episodes (N = 1703) Community-Acquired (n = 502) Healthcare...