... was discontinued afterwards. Case #1 completed 6 cycles of R-CHOP and 3 cycles of high-dose methotrexate 5 months later without evidence of recurrence at most recent follow-up in 2023. Repeat MRI in 2023 demonstrated stable postsurgical changes with no residual sellar mass ( Fig. 1C ). Physiologic replacement...

...) views. (A-C) Preoperative MRI showing a 5.1 × 3.1 × 2.2 cm sellar, supra-, infra-, and para-sellar mass (black arrow) that occupied the sphenoid sinuses inferiorly and invaded both cavernous sinus. The lesion had significant vertical growth, invaded the third ventricle, and caused obstructive...

..., and management of pituitary adenomas. Advances in surgical, medical, and radiation therapy are also reviewed. An improved understanding of this disease process will result in the adoption of less invasive and more efficacious treatments. sellar mass pituitary adenoma pathophysiology clinical presentation...