..., myelination defects, developmental delay, hypotonia and neuroregression. Our findings provide evidence in support of loss-of-function (LOF) as a genetic mechanism of EPB41L3-associated developmental disorder (EADD) using patient fibroblasts and Epb41l3-knocked down mouse oligodendroglia...

... Gürtel 18-20, A-1097 Vienna, Austria. E-mail: [email protected] © 2016 American Association of Neuropathologists, Inc. All rights reserved. 2016 Pathological protein deposits in oligodendroglia are common but variable features of various neurodegenerative conditions. To evaluate...

.... anaesthetics i.v., propofol developing brain neurones non-human primates oligodendroglia toxicity Editor's key points Exposure of fetal or neonatal non-human primates to ketamine or isoflurane anaesthesia causes widespread apoptosis. The effects of propofol were compared using the same NHP model...

... expand the spectrum of 4R tauopathies. Corticospinal tract Electron microscopy Immunohistochemistry Microglia Oligodendroglia Progressive supranuclear palsy Tauopathy. Some mid to late life neurodegenerative disorders are characterized by fibrillary cytoplasmic inclusions within neurons and glia...

.... glia multiple sclerosis astrocytes oligodendroglia AMPA = α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid ConA = concanavalin A CTZ: cyclothiazide EAE = experimental autoimmune encephalomyelitis GalC = galactocerebroside GFAP = glial fibrillary acidic protein GluR = glutamate receptor...

... for oligodendroglial and myelin pathology in the pathogenesis of PSP. Dentate nucleus Grumose degeneration Microglia Oligodendroglia Progressive supranuclear palsy Tau Grumose degeneration (GD) in the dentate nucleus was first described in progressive supranuclear palsy (PSP) ( 1 ). Subsequently, GD has been...

... storage disease Myelination Oligodendroglia ...

...,” including cortical laminar disorganization, columnar arrangement of cortical neurons, marked clustering of neurons throughout cortical layers II–VI, increased numbers of molecular layer neurons, marked perivascular clustering of oligodendroglia in the white matter, single heterotopic neurons in the deep...

...) and immunohistochemistry identified fragmented DNA of dead or dying glia and distinguished glial subtypes. Rare ISEL-positive oligodendroglia, astrocytes, and microglia were present in control brain. Apoptotic bodies and ISEL-positive glia significantly increased at PI day 1 in cortex and thalamus (p < 0.0S), but were...

... of the glial cells, in addition to extensive neurofibrillary tangles (NFTs) in the brains of Guam PDC and PDC-ALS patients. Granular hazy inclusions were seen in the astrocytes, and some crescent/coiled inclusions were observed in the oligodendroglia. Many granular hazy inclusions were observed...

...., Glenmont, N.Y. © 1995 by the American Association of Neuropathologists, Inc. 1995 Abstract Immunocytochemistry with antisera to transferrin has often been used to identify oligodendroglia in tissue sections and cultures, but reaction product also occurs in blood vessel walls and nerve cells...

...Takanori Hirose; Bernd W. Scheithauer; M. Beatriz S. Lopes; Scott R. VandenBerg Dysembryoplastic neuroepithelial tumor Glioneuronal lesion Immunohistochemistry Neurons Oligodendroglia Ultrastructure Abstract To assess the range of differentiation of the cells comprising dysembryoplastic...

... and prognostically important phenomenon. Arteriovenous malformation Brain tumor Oligodendroglia 01 48-396X/88/2306-0781%02.00/0 NEUROSURGERY Copyright C 1988 by the Congress of Neurological Surgeons Vol. 23, No. 6. 1988 Printed in U.S.A. Oligodendroglial Proliferative Abnormality Associated with Arteriovenous...

... and vascular components in the brain were involved and that the morphologic manifestations of the nervous component were far more extensive than those of the blood vessels. Astrocytes Capillary permeability Edema Myelin sheath Oligodendroglia Thiamine deficiency Wernicke's encephalopathy ...

... and research. prematurity encephalopathy white matter periventricular leukomalacia oligodendroglia preoligodendroglia visual impairment intellectual disability learning disability Encephalopathy of prematurity Neonatal disorders Perinatal brain damage injury Periventricular leukomalacia PVL...

... with reparative processes. astroglia glia microglia myelin nervous tissue oligodendroglia astrocytes glial cells macrophages described microglial cells neuroinflammation oligodendrocytes prenatal development Schwann cells Bergman cells in cerebellum blood flow cerebral blood vessels calcium...