... Rheumatology and Immunology, CHU Sainte-Justine, Department of Pediatrics, University of Montreal, CHU Sainte-Justine Research Center, 3175 Côte Sainte-Catherine, Montreal, Quebec H3T 1C5, Canada. E-mail: [email protected] cardiac neonatal lupus high-sensitivity cardiac troponin T Rheumatology key...

...A Pramono; L N Abdullah Complete heart block Neonatal Lupus Bradycardia Respiratory Distress Abstract Background Neonatal lupus (NL) is an autoimmune disease acquired in utero after exposure to antibodies produced by the maternal immune system against Ro and La antigens. It is considered...

... Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Background Neonatal lupus (NL) is an autoimmune disease acquired in utero after exposure to antibodies produced by the maternal immune system against Ro and La...

... with SLE dramatically increased the risk of preterm delivery and neonatal complications. Lay summary Neonatal lupus erythematosus (NLE) is the consequence of the transplacental passage of autoantibodies to newborns during pregnancy. The clinical features of NLE infants in our study were hemolytic...

.... undifferentiated connective tissue disease anti-nuclear antibodies pregnancy pregnancy complications autoimmune disease congenital heart block neonatal lupus autoantibodies Rheumatology key messages Women affected by UCTD are common in clinical practice. In our multicentre study of UCTD women we...

... with MCTD and aPL and pulmonary or muscular involvement had worse foetal outcomes compared with those without. Moreover, we report a case of complete congenital heart block (0.45%) and a case of cutaneous neonatal lupus, both born to a mother with positive isolated anti-U1RNP and negative anti-Ro/SSA...

...Hirokazu Arai; Hatsushi Nakajima; Nao Ogino; Tomoo Ito; Ryoji Goto; Yurina Kameta; Natsuki Ono; Naoko Hosoya; Hiroyuki Sanada; Tsutomu Takahashi Abstract This report describes the case of a very low-birth-weight male infant with neonatal lupus erythematosus. His mother had Sjögren’s syndrome...

... glomerulonephritis anti-phospholipid syndrome pregnancy counselling neonatal lupus preconception counselling Rheumatology key messages Recent pivotal studies have enabled us to more precisely estimate pregnancy prognosis and outcome in women with SLE. A multidisciplinary approach to pre-pregnancy...

... studies have suggested that prenatal exposure to HCQ reduces the risk of cardiac neonatal lupus. The aim of this study is to assess if maternal intake of antimalarials (AMs) throughout pregnancy lowered the risk of cardiac and non-cardiac neonatal lupus. Methods Consecutive children seen between 1...

... in anti-Ro52 antibody-positive pregnancies. anti-Ro52 antibodies AV block congenital heart block neonatal lupus erythematosus SSA Although anti-SSA/Ro autoantibodies, and more particularly anti-Ro52 antibodies, are found in approximately 90% of mothers of children with CHB, the risk for CHB is only 1...

... of neonatal lupus (cardiac NL) were examined to identify patterns of disease, gain insight into pathogenesis and enhance the search for biomarkers and preventive therapies. Methods. A retrospective analysis evaluating reports from 18 autopsies of cardiac NL cases and clinical data from the Research...

.... Oestrogen Systemic lupus erythematosus Rheumatoid arthritis Pregnancy Antiphospholipid syndrome Pre-eclampsia Neonatal lupus Systemic sclerosis Vasculitis Fertility Rheumatic diseases occur preferentially in women, often during the childbearing years. The female preponderance has raised...

... a 5-day-old infant who fulfilled the diagnostic criteria for Sweet’s syndrome, and the concurrent histologic and autoantibody features supporting the diagnosis of neonatal lupus. To our knowledge, this is the youngest case of Sweet’s syndrome reported in the literature. Importantly, our findings...

... and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Clin Exp Immunol 1995; 99:42-48 Anti-p57: a novel association with neonatal lupus p. J. MADDISON, L. LEEf, M...

...-La) proteins and polypeptides derived from the recombinant La protein in predicting fetal and neonatal outcome in children at risk to develop neonatal lupus erythematosus (NLE). All sera were obtained in the perinatal period and quantitative ELISA assays were used. We collected 41 maternal sera...

... not be used in the absence of symptoms; in the presence of alarming symptoms, betamethasone seems safer than dexamethasone. Heart block/congenital Neonatal lupus Systemic lupus erythematosus Sjogren's syndrome Undifferentiated connective tissue disease Dexamethasone Betamethasone Intravenous...

... Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) neonatal lupus erythematosus serological profile Male A was not investigated serologically. Females B (at 15 months), C and D (at 3 months) showed ANA positivity (1 : 160...

...-positive mothers. ECG abnormalities (first degree AV block and QTc interval prolongation) are frequent in infants of mothers with autoimmune diseases, independently of maternal disease, autoantibody profile and treatment during pregnancy. Anti-SSA/Ro antibodies ECG abnormalities Neonatal lupus QT...

... Perfezionamento, Università di Milano, Italy. Correspondence to: A. M. Stevens, Immunogenetics, D2-100, P.O. Box 19024, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, Seattle, WA 98109, USA. E-mail: [email protected] 27 6 2004 23 9 2004 Abstract Objective. Neonatal lupus...

... < 0.01 respectively). None of the 39 neonates from SLE mothers had neonatal lupus, anti‐Ro(SSA) or anti‐La(SSB) antibodies. Eight out of 59 pregnancies of SLE mothers (13.5%) were characterized by disease exacerbation. Arthralgias or arthritis, fever and skin lesions were observed more frequently...