...), Delhi and Madras Diabetes Research Foundation (MDRF/EC/EPI/2009/10), Chennai. Additionally, the study received approval from the Health Ministry Screening Committee of the Government of India. Abstract Background Early onset of menarche is associated with hormonal alterations that may predispose...

...=3,134) and menarche in females (N=4,424). Pubertal outcomes were parent-reported using the Pubertal Development Scale. We emulated sequential target trials to evaluate the effect of initiating and continuing melatonin supplement use. Findings were contrasted with comparisons of ever- to never-users...

..., provided the original work is properly cited. Abstract Aims Observational studies have shown a U-shaped association between age at menarche (AAM) and cardiovascular disease (CVD). We assessed non-linearity of the observational association and the potential causal relationship between AAM and CVD using...

...? SUMMARY ANSWER Maternal pregnancy history, particularly adverse outcomes, significantly influences the timing of menarche and the tempo of breast development in girls. WHAT IS KNOWN ALREADY Preliminary evidence indicates that parity may affect the onset of puberty, mainly as reflected by changes...

.../licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. Abstract Context Early age at menarche (AAM) is a risk factor for type 2 diabetes later in life...

... License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract STUDY QUESTION What is the association between reproductive health history (e.g. age at menarche, menopause...

... (interquartile range) of follow-up (between menarche and the date of HTN incidence or last follow-up) was 33.2 (25.1, 42.3) years. The event of menopause occurred in 31.8% of participants. The unadjusted model's findings illustrated that the EEE z-score was inversely associated with HTN incidence...

...., 2022 ). Studies have shown that early or late puberty timing is associated with the risk of various diseases in adulthood ( Day et al., 2015a ). Genome-wide association studies (GWAS) have identified more than 400 genetic loci for age at menarche (AAM) ( Elks et al., 2010 ; Demerath...

..., please email: [email protected] 2024 This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract STUDY QUESTION Is age at menarche associated...

... is associated with age at thelarche, pubarche and menarche. Maternal-reported questionnaire data measured puberty outcomes, PA in early childhood (ages 3–5 years) and total metabolic equivalents of organized PA in middle childhood (ages 7–9 years). We used interval-censored Weibull parametric survival...

... Cohort Cohort acronym Geographic location Participants Cases Calendar period of follow-up (range) Years of follow-up, mean (SD) Baseline age, mean (SD) Parity (live births), mean (range) Menarche age, mean (SD) Ever oral contraceptive use Ever menopausal hormone therapy use Hysterectomy...

... until the pre-industrial era, characterized by late menarche, very young age at first birth, multiple pregnancies, and prolonged periods of lactational amenorrhoea. For hundreds of thousands of years, menstruators experienced few ovulatory cycles, even though they were genetically adapted to ovulate...

... parameter found to be independently associated with IVM rate in a multivariable model was menarche status (F = 8.91, P = 0.004). Logistic regression models similarly showed that past chemotherapy exposure is negatively associated with successful retrieval of oocytes while older age...

...Yang Lv; Xing Xia; Lei Lei; Wei Xiang; Xuan Wu; Songbo Xie; Jie Li Abstract Background Observational studies have shown an association between age at menarche (AAM) and the risk of gynecological diseases. However, the causality cannot be determined due to residual confounding. Methods We...

... is properly cited. For commercial re-use, please contact [email protected] Abstract Background The roles of age at menarche and age at menopause in the etiology of lung and colorectal cancers are unclear. Objective We aimed to investigate potential causal associations between age at menarche...

...Ana Pereira; Pedro Ferrer; Alexandra Binder; Joanna Rojas; Karin B Michels; Camila Corvalán; Verónica Mericq In females, the average age at menarche has declined in the last 2 centuries from 17 years in the 1800s to 13 years in the mid-1900s ( 1 ) with small decreases thereafter ( 2 ). Similarly...

...D Susie Lee; Hanna Semenchenko Figure 2. A causal model depicts a postulated relationship between father absence and pubertal timing, as well as potential confounders. The directed acyclic graph was created using the R package ‘dagitty’ [ 57 ]. We used the child’s self-reported age at menarche...

..., and menarche in Chinese children. © The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: [email protected] 2023 This article is published and distributed under the terms of the Oxford University Press...

... Extremely early age at menarche, also called precocious puberty, has been associated with various cardiometabolic traits, but their shared heritability remains unclear. Objectives This work aimed to identify new shared genetic variants and their pathways for age at menarche and cardiometabolic traits...

...Marion Denos; Yi-Qian Sun; Ben Michael Brumpton; Arnulf Langhammer; Yue Chen; Xiao-Mei Mai colorectal cancer HUNT lung cancer menarche prospective cohort reproductive factors Norwegian Cancer Society 10.13039/100008730 182688-2016 funding from the Norwegian Women’s Public Health...