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Keywords: ischemic stroke
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Journal Article
Varicose vein is associated with an increased risk of ischemic stroke: a population-based matched cohort study
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Feng-Renn Hsieh and others
Postgraduate Medical Journal, qgaf063, https://doi.org/10.1093/postmj/qgaf063
Published: 30 April 2025
... From 1 January 2000 to 31 December 2015, adults with VVs were matched by propensity score with those without VVs. Patients with prior strokes were excluded. Follow-up continued until 31 December 2018. Outcomes Relative hazards through comparing incidence rates of ischemic stroke...
Journal Article
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Thrombolysis for acute ischemic stroke: development and update
Jiashuo Lin and others
Brain Communications, fcaf164, https://doi.org/10.1093/braincomms/fcaf164
Published: 28 April 2025
... of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Thrombolytic therapy is a cornerstone in managing acute ischemic stroke, marking...
Journal Article
The paradoxical relationship of sensorimotor deficit and lesion volume in acute ischemic stroke
Réka Tóth and others
Journal of Neuropathology & Experimental Neurology, nlaf046, https://doi.org/10.1093/jnen/nlaf046
Published: 24 April 2025
... the relationship between the degree of neurological deficit and lesion volume is key to predicting outcomes in patients with acute ischemic stroke (AIS). Over the past 40 years, AIS research has relied on a perceived linear relationship between lesion volumes and neurological deficit. Here, we found...
Journal Article
Implementation of regional Acute Stroke Care Map increases thrombolysis rates in urban areas of China: an interrupted time series analysis
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Rui Wen and others
International Journal for Quality in Health Care, Volume 37, Issue 2, 2025, mzaf022, https://doi.org/10.1093/intqhc/mzaf022
Published: 10 April 2025
... 4.5 hours of ischemic stroke onset in 30 hospitals. Using interrupted time series (ITS) analysis, it compares outcomes before and after ASCaM’s implementation from April 2019 to December 2021. The ASCaM strategy, featuring EMS prenotification, rapid triage, and immediate neuroimaging, is assessed...
Journal Article
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Unlocking the potential of regionally-activated injury/ischemia-induced stem cells for neural regeneration
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Takayuki Nakagomi
in
Stem Cells
Stem Cells, sxaf015, https://doi.org/10.1093/stmcls/sxaf015
Published: 01 April 2025
... (SVZ) is limited, and the precise repair mechanism active after ischemic stroke remains unknown. Consequently, it remains unclear how neural regeneration occurs in regions far from the SVZ, such as the cortex, especially given that these NSPCs can only migrate toward ischemic areas within specific...
Journal Article
Region-specific non-rapid eye movement delta activity is associated with stroke recovery
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Eric C Landsness and others
in
Sleep
Sleep, zsaf076, https://doi.org/10.1093/sleep/zsaf076
Published: 23 March 2025
... range (1.0–4.5 Hz) during non-rapid eye movement (NREM) sleep is crucial for brain plasticity and overall brain health. Recent research has shown that changes in NREM delta activity can occur locally, and activity can vary across different brain regions. Ischemic stroke results in focal brain injury...
Journal Article
Left atrial appendage occlusion: behind the bleeding risk
Giovanni Lorenzoni and others
European Heart Journal Supplements, Volume 27, Issue Supplement_1, February 2025, Pages i12–i15, https://doi.org/10.1093/eurheartjsupp/suae094
Published: 19 February 2025
... appendage in patients who are correctly taking oral anticoagulant therapy and who have an ischemic stroke. Abstract Atrial fibrillation (AF) is the most common arrhythmia in adults and is associated with an increased risk of embolic stroke. The main prevention strategy for cerebral embolic events is based...
Journal Article
Systolic Blood Pressure Modifies the Effect of Endovascular Thrombectomy in Acute Ischemic Stroke: A Mediation Analysis
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Dingkang Xu and others
American Journal of Hypertension, Volume 38, Issue 4, April 2025, Pages 206–216, https://doi.org/10.1093/ajh/hpae155
Published: 21 December 2024
... WH , Roos YBWEM , Van Der Lugt A , Van Oostenbrugge RJ , Majoie CBLM , Dippel DWJ. A randomized trial of intraarterial treatment for acute ischemic stroke . N Engl J Med 2015 ; 372 : 11 – 20 . 3. Yang P , Song L , Zhang Y , Zhang X , Chen...
Journal Article
NOD-like receptor X1 promotes autophagy and inactivates NLR family pyrin domain containing 3 inflammasome signaling by binding autophagy-related gene 5 to alleviate cerebral ischemia/reperfusion-induced neuronal injury
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Yufen Peng and others
Journal of Neuropathology & Experimental Neurology, Volume 84, Issue 3, March 2025, Pages 223–235, https://doi.org/10.1093/jnen/nlae129
Published: 20 December 2024
... brain damage in neonatal rats. 11 To date, the role of NLRX1 in CIRI and its regulatory effects on autophagy have not been studied fully. Abstract Ischemic strokes pose serious risks to human health. We aimed to elucidate the function of NOD-like receptor X1 (NLRX1) in a rat middle cerebral...
Journal Article
From acute lung injury to cerebral ischemia: a unified concept involving intercellular communication through extracellular vesicle-associated miRNAs released by macrophages/microglia
Xianbin Wang and others
Clinical and Experimental Immunology, Volume 219, Issue 1, 2025, uxae105, https://doi.org/10.1093/cei/uxae105
Published: 10 December 2024
... in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Ischemic stroke and acute lung injury are prevalent life-threatening conditions marked by intricate molecular mechanisms and elevated mortality rates. Despite evident...
Journal Article
Identification of hub genes and biological pathways related to central post-stroke pain in ischemic stroke
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Fude Liu and others
Human Molecular Genetics, Volume 34, Issue 4, 15 February 2025, Pages 304–312, https://doi.org/10.1093/hmg/ddae178
Published: 09 December 2024
... ) Abstract This investigation aims to screen ischemic stroke (IS)-related hub genes of central post-stroke pain (CPSP) from public databases and predict their potential roles through bioinformatics analysis to better interpret CPSP in IS. First, based on differential analysis, Venn analysis, and enrichment...
Journal Article
Impact of heart rate on eGFR decline in ischemic stroke patients
Jiann-Der Lee and others
Clinical Kidney Journal, Volume 18, Issue 1, January 2025, sfae387, https://doi.org/10.1093/ckj/sfae387
Published: 30 November 2024
... Patients with acute ischemic stroke accrued consecutively between 1 January 2010 and 30 September 2018 were included. The process for selecting patients with recent ischemic stroke was described in our previous study [ 17 ]. The exclusion criteria were patients (i) with follow-up of <1 year at our...
Journal Article
Serum Complement C1q in Egyptian Patients with Incidental Cerebral Small Vessel Disease
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Haitham El-Sayed Derbalah and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.182, https://doi.org/10.1093/qjmed/hcae175.182
Published: 20 November 2024
... ) Abstract Background Cerebral small vessel disease (CSVD) is associated with increased risk of death and ischemic stroke in patients with atherosclerotic disease. Identifying new biomarkers is mandatory for early diagnosis and proper management. Aim of the Study The aim of this study...
Journal Article
Relation of Serum Alpha 2-Antiplasmin to Clinical Response to Intravenous Recombinant Tissue Plasminogen Activator in Acute Ischemic Strokes without Large Vessel Occlusion
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Narges Wagih Mikhail and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.535, https://doi.org/10.1093/qjmed/hcae175.535
Published: 20 November 2024
... cerebrovascular stroke. Patients and Methods This is prospective cohort study was conducted at Ain Shams University Hospitals on acute ischemic stroke patients who received thrombolysis, met the inclusion and exclusion criteria. A blood sample to measure serum alpha 2-antiplasmin was obtained before receiving...
Journal Article
Role of Susceptibility Weighted Imaging (SWI) in Comparison to Magnetic Resonance Angiography in Assessment of the Intra-Arterial Thrombus in Patients with Acute Ischemic Stroke
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Gehan Mohamed Mohamed Ismaeel and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.919, https://doi.org/10.1093/qjmed/hcae175.919
Published: 20 November 2024
...Gehan Mohamed Mohamed Ismaeel; Nivan Hany Ahmed Khater; Mai Mokhtar Kamal Barakat Susceptibility Weighted Image acute ischemic stroke Magnetic Resonance Angiography © The Author(s) 2024. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved...
Journal Article
Stent Retriever versus Contact Aspiration in Management of Acute Ischemic Stroke; Egyptian Experience
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Hany Mohammed Amin Aref and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.509, https://doi.org/10.1093/qjmed/hcae175.509
Published: 20 November 2024
...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Background Mechanical thrombectomy (MT) has become the standard treatment in patients suffering from acute ischemic stroke (AIS) due to large vessel occlusion (LVO). It can be classified into thrombo‐aspiration, stent‐retrieval, and aspiration...
Journal Article
Correlation between D-Dimer and Size of Non-Lacunar MCA Infarction and its Relation to Functional Outcome
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Aya Ebrahim Marwan and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.500, https://doi.org/10.1093/qjmed/hcae175.500
Published: 20 November 2024
... correlation between plasma D-Dimer level and the ischemic lesion size of non-lacunar MCA infarction in MRI brain and predict functional outcome of these patients. Patients and Methods This cross sectional study Included 30 acute ischemic stroke (MCA) patients fulfilled the inclusion and exclusion criteria...
Journal Article
Thrombophilia Gene Testing in Patients with Ischemic Stroke of Undetermined Aetiology
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Mohamed Hamam Mohamed Eid and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.532, https://doi.org/10.1093/qjmed/hcae175.532
Published: 20 November 2024
... and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Background Ischemic stroke of undetermined aetiology represents a large patient group as it involves approximately 17% of all...
Journal Article
Machine learning-based prediction of one-year mortality in ischemic stroke patients
Ahmad Abujaber and others
Oxford Open Neuroscience, Volume 3, 2024, kvae011, https://doi.org/10.1093/oons/kvae011
Published: 14 November 2024
... medium, provided the original work is properly cited. Abstract Background: Accurate prediction of mortality following an ischemic stroke is essential for tailoring personalized treatment strategies. This study evaluates the effectiveness of machine learning models in predicting one-year mortality after...
Journal Article
Predicting functional outcome in ischemic stroke patients using genetic, environmental, and clinical factors: a machine learning analysis of population-based prospective cohort study
Siding Chen and others
Briefings in Bioinformatics, Volume 25, Issue 6, November 2024, bbae487, https://doi.org/10.1093/bib/bbae487
Published: 13 October 2024
...-Commercial License ( https://creativecommons.org/licenses/by-nc/4.0/ ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Ischemic stroke...
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